Results 41 to 50 of about 281,068 (243)
Microbiome Intervention Analysis with Transfer Functions and Mirror Statistics [PDF]
arXiv, 2023 Microbiome interventions provide valuable data about microbial ecosystem structure and dynamics. Despite their ubiquity in microbiome research, few rigorous data analysis approaches are available. In this study, we extend transfer function-based intervention analysis to the microbiome setting, drawing from advances in statistical learning and selective
arxiv
Frontiers in MicrobiomesThe recent FDA approvals of Rebyota™ and Vowst™ represent landmark milestones within the burgeoning field of live microbiota-based products. Future microbiota-based treatment approaches also hold significant promise for treating patients with a myriad of
Microbiome Therapeutics Innovation Group +1 more
doaj +1 more source
Rough Set Microbiome Characterisation [PDF]
arXiv, 2021 Microbiota profiles measure the structure of microbial communities in a defined environment (known as microbiomes). In the past decade, microbiome research has focused on health applications as a result of which the gut microbiome has been implicated in the development of a broad range of diseases such as obesity, inflammatory bowel disease, and major ...
arxiv
The Microbiome and Asthma [PDF]
Annals of the American Thoracic Society, 2014 That the subglottic airways are not sterile, as was once believed, but are populated by a distinct "bronchial microbiome," is now accepted. Also accepted is the concept that asthma is associated with differences in the composition of this microbiome.
Huang, Yvonne J, Boushey, Homer A
openaire +5 more sources
BMC Genomics, 2018 Background Bifidobacterium longum is a common member of the human gut microbiota and is frequently present at high numbers in the gut microbiota of humans throughout life, thus indicative of a close symbiotic host-microbe relationship.
Silvia Arboleya +6 more
doaj +1 more source
mBio, 2021 New therapeutics are urgently needed in the fight against COVID-19. Repurposing drugs that are either already approved for human use or are in advanced stages of the approval process can facilitate more rapid advances toward this goal.
Nathan E. Stone +16 more
doaj +1 more source
HT-MMIOW: A Hypothesis Test approach for Microbiome Mediation using Inverse Odds Weighting [PDF]
arXiv, 2023 The human microbiome has an important role in determining health. Mediation analyses quantify the contribution of the microbiome in the causal path between exposure and disease; however, current mediation models cannot fully capture the high dimensional, correlated, and compositional nature of microbiome data and do not typically accommodate ...
arxiv
Scientific Reports, 2021 The mechanisms through which cells of the host innate immune system distinguish commensal bacteria from pathogens are currently unclear. Toll-like receptors (TLRs) are a class of pattern recognition receptors (PRRs) expressed by host cells which ...
Sreeram Udayan +8 more
doaj +1 more source
The gut microbiome in social anxiety disorder: evidence of altered composition and function
Translational Psychiatry, 2023 The microbiome-gut-brain axis plays a role in anxiety, the stress response and social development, and is of growing interest in neuropsychiatric conditions.
Mary I. Butler +13 more
doaj +1 more source
Variable selection for sparse Dirichlet-multinomial regression with an application to microbiome data analysis [PDF]
Annals of Applied Statistics 2013, Vol. 7, No. 1, 418-442, 2013 With the development of next generation sequencing technology, researchers have now been able to study the microbiome composition using direct sequencing, whose output are bacterial taxa counts for each microbiome sample. One goal of microbiome study is to associate the microbiome composition with environmental covariates.
arxiv +1 more source