Results 51 to 60 of about 675,129 (379)

What is a hologenomic adaptation? Emergent individuality and inter-identity in multispecies systems [PDF]

, 2020
Contemporary biological research has suggested that some host–microbiome multispecies systems (referred to as “holobionts”) can in certain circumstances evolve as unique biological individual, thus being a unit of selection in evolution.
Arnellos, Austin, Austin, Austin, Bedau, Bigelow, Boogerd, Boorse, Booth, Bordenstein, Bouchard, Bouchard, Bouchard, Bouchard, Bouchard, Bourrat, Brooks, Brucker, Brucker, Brucker, Burke, Campbell, Canciani, Catania, Chalmers, Chandler, Chiu, Chiu, Chong, Clarke, Clarke, Dethlefsen, DiFrisco, Doolittle, Douglas, Dupré, Dupré, Dupré, Dupré, Díaz, Gilbert, Gilbert, Gilbert, Gilbert, Gilbert, Gilbert, Godfrey-Smith, Godfrey-Smith, Godfrey-Smith, Godfrey-Smith, Godfrey-Smith, Godfrey-Smith, Grant, Grant, Green, Guay, Hester, Humphreys, Hurst, Hölldobler, Kim, Kim, Kitcher, Koga, Kushmaro, Laplane, Lemanceau, Lewontin, Lidgard, Lloyd, Lloyd, Lloyd, Lloyd, Lloyd, Louca, Lowe, Maynard-Smith, Mayr, Mazel, McCall, McCall, Mendoza, Miller, Miller, Millikan, Mitchell, Moran, Moreno, Mossio, Mossio, Mumford, Nicholson, Nicholson, Nicholson, Okasha, O’Connor, O’Connor, Pepper, Pradeu, Pradeu, Pradeu, Pradeu, Queller, Reshef, Rosenberg, Rosenberg, Rosenberg, Roughgarden, Rudman, Sapp, Sartenaer, Silberstein, Skillings, Sober, Sober, Sober, Stencel, Stencel, Stencel, Suárez, Suárez, Suárez, Suárez, Taxis, Theis, Thompson, Triviño, Triviño, Uhr, van Gulick, Walsh, Waters, Wiggins, Williams, Wilson, Wilson, Wilson, Wilson, Wright, Zilber-Rosenberg   +139 more
core   +2 more sources

Gene-trait matching across the Bifidobacterium longum pan-genome reveals considerable diversity in carbohydrate catabolism among human infant strains

BMC Genomics, 2018
Background Bifidobacterium longum is a common member of the human gut microbiota and is frequently present at high numbers in the gut microbiota of humans throughout life, thus indicative of a close symbiotic host-microbe relationship.
Silvia Arboleya, Francesca Bottacini, Mary O’Connell-Motherway, C. Anthony Ryan, R. Paul Ross, Douwe van Sinderen, Catherine Stanton   +6 more
doaj   +1 more source

Microbiomes for All [PDF]

Frontiers in Microbiology, 2020
Microbiome research projects are often interdisciplinary, involving fields such as microbiology, genetics, ecology, evolution, bioinformatics, and statistics. These research projects can be an excellent fit for undergraduate courses ranging from introductory biology labs to upper-level capstone courses.
Theodore R. Muth, Theodore R. Muth, Avrom J. Caplan   +2 more
openaire   +3 more sources

Enhanced Characterization of Drug Metabolism and the Influence of the Intestinal Microbiome: A Pharmacokinetic, Microbiome, and Untargeted Metabolomics Study. [PDF]

, 2020
Determining factors that contribute to interindividual and intra-individual variability in pharmacokinetics (PKs) and drug metabolism is essential for the optimal use of drugs in humans.
Alhaja, Maher, Dorrestein, Pieter C, Jarmusch, Alan K, Knight, Rob, Liyanage, Marlon, Ma, Joseph D, Momper, Jeremiah D, Tsunoda, Shirley M, Vrbanac, Alison   +8 more
core   +1 more source

Navigating regulatory and analytical challenges in live biotherapeutic product development and manufacturing

Frontiers in Microbiomes
The recent FDA approvals of Rebyota™ and Vowst™ represent landmark milestones within the burgeoning field of live microbiota-based products. Future microbiota-based treatment approaches also hold significant promise for treating patients with a myriad of
Microbiome Therapeutics Innovation Group, Dana Barberio   +1 more
doaj   +1 more source

The nasopharyngeal microbiome

Emerging Topics in Life Sciences, 2017
Human microbiomes have received increasing attention over the last 10 years, leading to a pervasiveness of hypotheses relating dysbiosis to health and disease. The respiratory tract has received much less attention in this respect than that of, for example, the human gut. Nevertheless, progress has been made in elucidating the immunological, ecological
David W, Cleary, Stuart C, Clarke
openaire   +3 more sources

Reproducible protocols for metagenomic analysis of human faecal phageomes

Microbiome, 2018
Background Recent studies have demonstrated that the human gut is populated by complex, highly individual and stable communities of viruses, the majority of which are bacteriophages.
Andrey N. Shkoporov, Feargal J. Ryan, Lorraine A. Draper, Amanda Forde, Stephen R. Stockdale, Karen M. Daly, Siobhan A. McDonnell, James A. Nolan, Thomas D.S. Sutton, Marion Dalmasso, Angela McCann, R. Paul Ross, Colin Hill   +12 more
doaj   +1 more source

Microbiome and Gluten [PDF]

Annals of Nutrition and Metabolism, 2015
Celiac disease (CD) is a frequent chronic inflammatory enteropathy caused by gluten in genetically predisposed individuals that carry disease susceptibility genes (HLA-DQ2/8). These genes are present in about 30-40% of the general population, but only a small percentage of carriers develops CD.
openaire   +2 more sources

Perinatal factors affect the gut microbiota up to four years after birth

Nature Communications, 2019
Early life microbiome is affected by factors such as mode of delivery, gestational age at birth and feeding regime. Here, the authors show that gestational age at birth still imprints on the microbiome at four years of age, suggesting a link between ...
Fiona Fouhy, Claire Watkins, Cian J. Hill, Carol-Anne O’Shea, Brid Nagle, Eugene M. Dempsey, Paul W. O’Toole, R. Paul Ross, C. Anthony Ryan, Catherine Stanton   +9 more
doaj   +1 more source

The cancer microbiome [PDF]

Nature Reviews Cancer, 2019
Collectively known as the microbiota, the commensal bacteria and other microorganisms that colonize the epithelial surfaces of our body have been shown to produce small molecules and metabolites that have both local and systemic effects on cancer onset, progression and therapy response.
Eran Elinav, Wendy S. Garrett, Giorgio Trinchieri, Jennifer Wargo   +3 more
openaire   +2 more sources