Results 51 to 60 of about 510,029 (347)

Autochthonous faecal viral transfer (FVT) impacts the murine microbiome after antibiotic perturbation

open access: yesBMC Biology, 2020
Background It has become increasingly accepted that establishing and maintaining a complex and diverse gut microbiota is fundamental to human health. There are growing efforts to identify means of modulating and influencing the microbiota, especially in ...
Lorraine A. Draper   +7 more
doaj   +1 more source

Whole genome metagenomic analysis of the gut microbiome of differently fed infants identifies differences in microbial composition and functional genes, including an absent CRISPR/Cas9 gene in the formula-fed cohort [PDF]

open access: yes, 2019
Background: Advancements in sequencing capabilities have enhanced the study of the human microbiome. There are limited studies focused on the gastro-intestinal (gut) microbiome of infants, particularly the impact of diet between breast-fed (BF) versus ...
Cox, Courtney   +3 more
core   +2 more sources

Improvements in Gut Microbiome Composition Predict the Clinical Efficacy of a Novel Synbiotics Formula in Children with Mild to Moderate Atopic Dermatitis

open access: yesMicroorganisms, 2023
Atopic dermatitis (AD) is a common chronic inflammatory skin disease with a significant association with various type-2 inflammation-related comorbidities. Ongoing research suggests the crucial involvement of gut microbiome, especially in childhood onset
Chi Tung Choy   +9 more
doaj   +1 more source

Extreme Dysbiosis of the Microbiome in Critical Illness. [PDF]

open access: yes, 2016
Critical illness is hypothesized to associate with loss of "health-promoting" commensal microbes and overgrowth of pathogenic bacteria (dysbiosis). This dysbiosis is believed to increase susceptibility to nosocomial infections, sepsis, and organ failure.
Christine Baird   +12 more
core   +2 more sources

Navigating regulatory and analytical challenges in live biotherapeutic product development and manufacturing

open access: yesFrontiers in Microbiomes
The recent FDA approvals of Rebyota™ and Vowst™ represent landmark milestones within the burgeoning field of live microbiota-based products. Future microbiota-based treatment approaches also hold significant promise for treating patients with a myriad of
Microbiome Therapeutics Innovation Group   +1 more
doaj   +1 more source

Gut Microbial Metabolism and Nonalcoholic Fatty Liver Disease. [PDF]

open access: yes, 2019
The gut microbiome, the multispecies community of microbes that exists in the gastrointestinal tract, encodes several orders of magnitude more functional genes than the human genome. It also plays a pivotal role in human health, in part due to metabolism
Lynch, Susan V   +3 more
core   +1 more source

The nasopharyngeal microbiome

open access: yesEmerging Topics in Life Sciences, 2017
Human microbiomes have received increasing attention over the last 10 years, leading to a pervasiveness of hypotheses relating dysbiosis to health and disease. The respiratory tract has received much less attention in this respect than that of, for example, the human gut. Nevertheless, progress has been made in elucidating the immunological, ecological
Cleary, David W., Clarke, Stuart C.
openaire   +5 more sources

The microbiome in spondyloarthritis

open access: yesBest Practice & Research Clinical Rheumatology, 2019
A causal link between the wealth of microbes that populate our body surfaces, designated as microbiota, and inflammatory disorders, including ankylosing spondylitis and the related spondyloarthritis (SpA) has been suspected for decades. This specially concerns the gut microbiota that became only recently accessible to thorough description thanks to ...
Marie Beaufrère   +3 more
openaire   +5 more sources

TNF-α synergises with IFN-γ to induce caspase-8-JAK1/2-STAT1-dependent death of intestinal epithelial cells

open access: yesCell Death and Disease, 2021
Rewiring of host cytokine networks is a key feature of inflammatory bowel diseases (IBD) such as Crohn’s disease (CD). Th1-type cytokines—IFN-γ and TNF-α—occupy critical nodes within these networks and both are associated with disruption of gut ...
Jerzy A. Woznicki   +18 more
doaj   +1 more source

Synchronous genitourinary lichen sclerosus signals a distinct urinary microbiome profile in men with urethral stricture disease. [PDF]

open access: yes, 2021
PurposeAlterations in the urinary microbiome have been associated with urological diseases. The microbiome of patients with urethral stricture disease (USD) remains unknown.
Breyer, Benjamin N   +9 more
core   +1 more source

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