Results 81 to 90 of about 691,309 (371)

microViz: an R package for microbiome data visualization and statistics

Journal of Open Source Software, 2021
microViz is an R package for the statistical analysis and visualization of microbiota data. This package extends the functionality of popular microbial ecosystem data analysis R packages, including phyloseq (McMurdie & Holmes, 2013), vegan (Oksanen et al.
David J. M. Barnett, I. Arts, J. Penders
semanticscholar   +1 more source

Relapsing–Remitting Multiple Sclerosis Is Associated With a Dysbiotic Oral Microbiome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neurological impairment. While the gut microbiota's role in MS is extensively studied, the association between the oral microbiota and MS remains underexplored, particularly in North American cohorts.
Sukirth M. Ganesan, Meeta Yadav, Sudeep Ghimire, Peter C. Lehman, Apurva J. Patel, Sydney Woods, Heena Olalde, Jemmie Hoang, Mishelle Paullus, Catherine Cherwin, Christine Gill, Tracey Cho, Ashutosh K. Mangalam   +12 more
wiley   +1 more source

Microbial regulation of microRNA expression in the amygdala and prefrontal cortex

Microbiome, 2017
Background There is growing evidence for a role of the gut microbiome in shaping behaviour relevant to many psychiatric and neurological disorders.
Alan E. Hoban, Roman M. Stilling, Gerard M. Moloney, Rachel D. Moloney, Fergus Shanahan, Timothy G. Dinan, John F. Cryan, Gerard Clarke   +7 more
doaj   +1 more source

Microneedle‐Based Biofertilizer Delivery Improves Plant Growth Through Microbiome Engineering

Advanced Functional Materials, EarlyView.
This figure shows how microneedles are used to deliver biofertilizers to enhance plant growth through microbial migration, metabolic reprogramming, and changes in plant endogenous microbiome. Abstract This study presents a microneedle‐based system for the delivery of rhizospheric biofertilizers into plant tissues to enhance growth.
Zhicheng Le, Sevugan Mayalagu, Cheng‐Yen Chen, Raktim Bhattacharya, Abhishek Gupta, Jingyuan Li, Zhi Wei Norman Teo, Yufeng Shou, Arya Gopinath MP, Danni Zhong, Tedrick Thomas Salim Lew, Hao Yu, Naweed I. Naqvi, Sanjay Swarup, Andy Tay   +14 more
wiley   +1 more source

The gut microbiome as a modulator of healthy ageing

Nature reviews: Gastroenterology & hepatology, 2022
The gut microbiome is a contributory factor in ageing-related health loss and in several non-communicable diseases in all age groups. Some age-linked and disease-linked compositional and functional changes overlap, while others are distinct.
T. Ghosh, F. Shanahan, P. O’Toole
semanticscholar   +1 more source

Membrane Vesicles from Lacticaseibacillus Casei BL23 Exhibit Antimicrobial Activity Against Escherichia coli and Immunostimulatory Effects on Human Peripheral Blood Mononuclear Cells

Advanced Healthcare Materials, EarlyView.
Membrane vesicles derived from the probiotic Lacticaseibacillus casei BL23 demonstrate antimicrobial properties against Escherichia coli and a potential biological effect in improving the overall survival of C. elegans infected with Pseudomonas aeruginosa. These vesicles stimulated immune responses in primary cells without causing toxicity. Our results
Cecilia L. D'Antoni, Leila Pourtalebi Jahromi, Lorenzo Sana, Ana Paula Domínguez Rubio, Maja Dorfner, Jennifer Munkert, Heike Danzer, Philipp Arnold, Mikhail Lebedev, Esther Zanin, Oscar E. Pérez, Gregor Fuhrmann   +11 more
wiley   +1 more source

TNF-α synergises with IFN-γ to induce caspase-8-JAK1/2-STAT1-dependent death of intestinal epithelial cells

Cell Death and Disease, 2021
Rewiring of host cytokine networks is a key feature of inflammatory bowel diseases (IBD) such as Crohn’s disease (CD). Th1-type cytokines—IFN-γ and TNF-α—occupy critical nodes within these networks and both are associated with disruption of gut ...
Jerzy A. Woznicki, Nisha Saini, Peter Flood, Subhasree Rajaram, Ciaran M. Lee, Panagiota Stamou, Agnieszka Skowyra, Milan Bustamante-Garrido, Karine Regazzoni, Nyree Crawford, Simon S. McDade, Daniel B. Longley, Pedro Aza-Blanc, Fergus Shanahan, Syed A. Zulquernain, Jane McCarthy, Silvia Melgar, Bradford L. McRae, Ken Nally   +18 more
doaj   +1 more source

Unweighted Unifrac is a theoretically better measure for dietary and cardiometabolic data [PDF]

, 2018
The objective of this report was to compare unweighted and weighted Unifrac statistical methods and decide which method is best for analyzing dietary and cardiometabolic data.
Pilles, Kiona Natasha
core   +1 more source

A Sacrificial 3D Printed Vessel‐on‐Chip Demonstrates a Versatile Approach to Model Granulation Tissue

Advanced Healthcare Materials, EarlyView.
A novel method that combines 3D printing and organ‐on‐chip technology enables the creation of hollow channels lined with endothelial cells through a fibroblast‐populated connective tissue matrix. The model supports stable metabolic culture conditions, angiogenic sprouting, and immune cell migration, thereby demonstrating an easy and versatile method to
Jonas Jäger, Phil Berger, Andrew I. Morrison, Hendrik Erfurth, Maria Thon, Eva‐Maria Dehne, Susan Gibbs, Jasper J. Koning   +7 more
wiley   +1 more source

Characterization of GH2 and GH42 β-galactosidases derived from bifidobacterial infant isolates

AMB Express, 2019
Bifidobacteria are among the first and most abundant bacterial colonizers of the gastrointestinal tract of (breast-fed) healthy infants. Their success of colonising the infant gut is believed to be, at least partly, due to their ability to metabolize ...
Valentina Ambrogi, Francesca Bottacini, Joyce O’Sullivan, Mary O’Connell Motherway, Cao Linqiu, Barry Schoemaker, Margriet Schoterman, Douwe van Sinderen   +7 more
doaj   +1 more source