Results 101 to 110 of about 875,448 (383)

Entry of spores into intestinal epithelial cells contributes to recurrence of Clostridioides difficile infection

Nature Communications, 2021
Spores produced by Clostridioides difficile during infection are important for the recurrence of the disease. Here, Castro-Córdova et al. show that the spores gain entry into the intestinal mucosa via pathways dependent on host fibronectin and ...
Pablo Castro-Córdova, Paola Mora-Uribe, Rodrigo Reyes-Ramírez, Glenda Cofré-Araneda, Josué Orozco-Aguilar, Christian Brito-Silva, María José Mendoza-León, Sarah A. Kuehne, Nigel P. Minton, Marjorie Pizarro-Guajardo, Daniel Paredes-Sabja   +10 more
doaj   +1 more source

Long-term impact of fecal transplantation in healthy volunteers [PDF]

, 2019
Fecal microbiota transplantation (FMT) has been recently approved by FDA for the treatment of refractory recurrent clostridial colitis (rCDI). Success of FTM in treatment of rCDI led to a number of studies investigating the effectiveness of its ...
Egozcue Rubí, Juan José, Goloshchapov, Oleg V., Olekhnovich, Evgenii I., Sidorenko, Sergey V.   +3 more
core   +2 more sources

Colon‐Targeted Natural Polysaccharide‐Berberine Armored Hydrogel for the Treatment of Colitis

Advanced Healthcare Materials, EarlyView.
In this research, a novel hydrogel system targeting the colon is developed, incorporating Rhubarb polysaccharides and berberine‐loaded dendrimer. This hydrogel, forms through intermolecular hydrogen bonding and electrostatic interactions, accumulates in colonic tissues, effectively alleviating pathological immune hyperactivation while modulating gut ...
Miao Guo, Bo Li, Hongyi Li, Yi Chen, Qin Yuan, Mingju Shui, Hefeng Zhou, Wei Hao, Shengpeng Wang   +8 more
wiley   +1 more source

The Role of Targeted Microbiota Therapy in the Prevention and Management of Puerperal Mastitis

Diseases
Mastitis, an inflammatory condition of the breast, significantly affects breastfeeding women and can lead to the early cessation of lactation. This article explores the pathophysiology of mastitis, distinguishing between acute mastitis (AM) and subacute ...
Mariarosaria Matera, Chiara Maria Palazzi, Alexander Bertuccioli, Francesco Di Pierro, Nicola Zerbinati, Massimiliano Cazzaniga, Aurora Gregoretti, Ilaria Cavecchia   +7 more
doaj   +1 more source

TGFβ/BMP immune signaling affects abundance and function of C. elegans gut commensals. [PDF]

, 2019
The gut microbiota contributes to host health and fitness, and imbalances in its composition are associated with pathology. However, what shapes microbiota composition is not clear, in particular the role of genetic factors.
Berg, Maureen, Cho, Juhyun, Crits-Christoph, Alex, Monnin, David, Nelson, Lydia, Shapira, Michael   +5 more
core   +2 more sources

Advanced Oral Delivery Systems for Nutraceuticals

Advanced Healthcare Materials, EarlyView.
Emerging delivery technologies are explored to overcome barriers to oral nutraceutical absorption. Traditional carriers are compared with novel platforms including biodegradable polymers, MOFs, MPNs, and 3D printing. These systems enhance bioavailability, control release, and enable personalized nutrition.
Xin Yang, Linzixuan Zhang, Zhiling Zheng, Robert Langer, Ana Jaklenec   +4 more
wiley   +1 more source

Assessing the impact of hatching system and body weight on the growth performance, caecal short-chain fatty acids, and microbiota composition and functionality in broilers

Animal Microbiome
Background Variations in body weight (BW) remain a significant challenge within broiler flocks, despite uniform management practices. Chicken growth traits are influenced by gut microbiota, which are in turn shaped by early-life events like different ...
Muhammad Zeeshan Akram, Ester Arévalo Sureda, Luke Comer, Matthias Corion, Nadia Everaert   +4 more
doaj   +1 more source

Variable responses of human and non-human primate gut microbiomes to a Western diet [PDF]

, 2015
BACKGROUND: The human gut microbiota interacts closely with human diet and physiology. To better understand the mechanisms behind this relationship, gut microbiome research relies on complementing human studies with manipulations of animal models ...
Amato, Katherine R., Cerda, Gabriela, Cramer, Jennifer Danzy, Gomez, Andres, Knight, Rob, Leigh, Steven R., Miller, Margret E. Berg, Nelson, Karen E., Schmitt, Christopher A., Stumpf, Rebecca M., Turner, Trudy R., White, Bryan A., Wilson, Brenda A., Yeoman, Carl J.   +13 more
core   +5 more sources

Epigenomics and the Microbiota [PDF]

Toxicologic Pathology, 2014
The mammalian gastrointestinal tract is home to trillions of commensal microorganisms that collectively make up the intestinal microbiota. These microbes are important environmental factors that regulate homeostasis, and alterations in the composition of the microbiota have been associated with several diseases, including inflammatory bowel disease ...
openaire   +3 more sources

Mucosa‐Interfacing Capsule for In Situ Sensing the Elasticity of Biological Tissues

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
A fundamental mechanism of palpating soft materials is reported to sense deep tissue elasticity in situ with minimal invasion using the interaction between the robot palpation unit and soft tissues. Both the robot locomotion and elasticity sensing functions are remotely controlled by external magnetic fields, while the sensing data are wirelessly ...
Kiyoung Kim, Steven Edwards, Kyle Fuxa, Honglu Lin, Shreya Shrestha, Hanwen Fan, Nick Diaz, Joel Berinstein, Rishi Naik, Yuxiao Zhou, Xiaoguang Dong   +10 more
wiley   +1 more source