Results 121 to 130 of about 356,233 (321)
Engineered Probiotics Mitigate Gut Barrier Dysfunction Induced by Nanoplastics
Intestinal barrier stability is vital for gut health. Plastic polyethylene terephthalate (PET) disrupts this barrier, causing inflammation and infections. This study encodes transforming growth factor‐β into EcN and modifies its surface with pH‐responsive polymer (EcNT@L), creating an oral drug delivery system to repair nano PET‐induced intestinal ...
Wenxin Chen+9 more
wiley +1 more source
Influence of Indigenous Microbiota on Amount of Protein and Activities of Alkaline Phosphatase and Disaccharidases in Extracts of Intestinal Mucosa in Mice [PDF]
Dixie D. Whitt, Dwayne C. Savage
openalex +1 more source
The gut microbiome is a potential target for treating cardiovascular disease. It is found that prophylactic administration of Flavonifractor plautii or its metabolite desaminotyrosine (DAT) exerts pleiotropic cardioprotective effects via promoting cardiomyocyte survival and attenuating cardiac inflammation against myocardial ischemia/reperfusion (I/R ...
Heng Du+21 more
wiley +1 more source
Assessment of Perceived Effort Through On-Field Hydration Monitoring: A Case Analysis
This case report examines the correlation between hydration, weight variation, and perceived effort in a 43-year-old amateur athlete during a self-supported 81.5 km crossing of Death Valley, completed over 3 days with significant elevation changes ...
Alexander Bertuccioli+11 more
doaj +1 more source
Integrating network pharmacology, metabolomics, and gut microbiota analysis to explore the effects of Jinhong tablets on chronic superficial gastritis [PDF]
Chronic superficial gastritis (CSG) severely affects quality of life and can progress to worse gastric pathologies. Traditional Chinese Medicine (TCM) effectively treats CSG, as exemplified by Jinhong Tablets (JHT) with known anti-inflammatory properties, though their mechanism remains unclear.
arxiv
A CO‐releasing polyoxometalates nanozyme (PMC) is engineered by coordinating pentacarbonyl manganese bromide with molybdenum‐based polyoxometalates nanoclusters. PMC exhibits targeted accumulation at IBD sites, efficient ROS scavenging, and responsive CO release.
Hongyang Lu+16 more
wiley +1 more source
Acid digestion and symbiont: Proton sharing at the origin of mitochondriogenesis?
ADMit hypothesis for the origin of eukaryotes. A bacterial symbiont became associated with a protophagocytic host that captured prey with membrane processes. The symbiont cooperated to kill and digest the prey with reactive oxygen species and the acidification of the microenvironment.
Mario Mencía
wiley +1 more source
Topological Data Analysis of Clostridioides difficile Infection and Fecal Microbiota Transplantation [PDF]
Computational topologists recently developed a method, called persistent homology to analyze data presented in terms of similarity or dissimilarity. Indeed, persistent homology studies the evolution of topological features in terms of a single index, and is able to capture higher order features beyond the usual clustering techniques.
arxiv
This work summarizes the efficacy and mechanisms of probiotics in CRC treatment, providing a comprehensive overview of various encapsulation methods such as microcapsules, hydrogels, single‐cell nanocoatings, and nanofibers for targeted probiotic delivery to inflammatory sites, with particular emphasis on the potential advantages of emerging single ...
Hao Zhong+5 more
wiley +1 more source