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The regulation of host defences to infection by the microbiota [PDF]
The skin and mucosal epithelia of humans and other mammals are permanently colonised by large microbial communities (the microbiota). Due to this life-long association with the microbiota, these microbes have an extensive influence over the physiology of
Brown, RL, Clarke, TB
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A Microbiota Assimilation [PDF]
While the gut microbiota's malleability makes it highly responsive to our environment, it also renders it susceptible to rapid selection by factors associated with an industrialized lifestyle. Recently, in Cell, Vangay et al. (2018) have tracked and revealed rapid and profound changes in the gut community of immigrants to one that resembles long-term ...
Justin L. Sonnenburg+1 more
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Invasion of intestinal cells by Staphylococcus warneri, a member of the human gut microbiota
Coagulase negative staphylococci (CoNS) are a heterogeneous group of bacteria that colonize different types of human epithelia. These bacteria have a highly variable pathogenic potential ranging from avirulent species to major nosocomial pathogens ...
Robin Louail+8 more
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Diet contributes to urban-induced alterations in gut microbiota : experimental evidence from a wild passerine [PDF]
Urban sprawl increasingly affects the ecology of natural populations, including host-microbiota interactions, with observed differences in the gut microbiota between urban and rural hosts.
De Neve, Liesbeth+5 more
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Gut Microbiota and Neuroplasticity [PDF]
The accumulating evidence linking bacteria in the gut and neurons in the brain (the microbiota–gut–brain axis) has led to a paradigm shift in the neurosciences. Understanding the neurobiological mechanisms supporting the relevance of actions mediated by the gut microbiota for brain physiology and neuronal functioning is a key research area.
Julia Murciano-Brea+3 more
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Autoimmunity and microbiota [PDF]
Environment (physical insults, toxins, nutrition and microorganisms) influences development of autoimmune diseases. Pathogenic, pathobiotic and commensal microorganisms contribute to disease progression in genetically susceptible hosts. Germ-free animals or defined-microbiota colonized animals are valuable tools for understanding microbial influences ...
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Inflammation-associated enterotypes, host genotype, cage and inter-individual effects drive gut microbiota variation in common laboratory mice [PDF]
Background: Murine models are a crucial component of gut microbiome research. Unfortunately, a multitude of genetic backgrounds and experimental setups, together with inter-individual variation, complicates cross-study comparisons and a global ...
Brinkman, Brigitta+7 more
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AbstractWe examine 3 different approaches to protecting the gut microbiome: highly targeted antibiotics, antibiotic destruction, and antibiotic binding. Each approach shows promise to prevent the off-target effects of antibiotics on the gut microbiome.
S Ahmed+5 more
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Microbiota and faecal microbiota transplant
As the range of disease states associated with the gut microbiome expands – and the mechanistic links between the gut microbiome and host physiology further deepens – so interest also grows in microbiome manipulation as medical therapy. In particular, bolstered by its established role in recurrent C.
Mullish, BH, Alexander, JL, Segal, JP
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Antibiotics and probiotics impact gut antimicrobial resistance gene reservoir in COVID-19 patients
Dysbiosis of gut microbiota is well-described in patients with coronavirus 2019 (COVID-19), but the dynamics of antimicrobial resistance genes (ARGs) reservoir, known as resistome, is less known.
Qi Su+15 more
doaj +1 more source