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The Journal of Infectious Diseases, 2021 AbstractWe examine 3 different approaches to protecting the gut microbiome: highly targeted antibiotics, antibiotic destruction, and antibiotic binding. Each approach shows promise to prevent the off-target effects of antibiotics on the gut microbiome.
S Ahmed +5 more
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Microorganisms, 2022 Clostridioides difficile is Gram-positive spore-former bacterium and the leading cause of nosocomial antibiotic-associated diarrhea. During disease, C. difficile forms metabolically dormant spores that persist in the host and contribute to recurrence of ...
Nicolás Montes-Bravo +5 more
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Autoimmunity and microbiota [PDF]
Journal of Translational Medicine, 2011 Environment (physical insults, toxins, nutrition and microorganisms) influences development of autoimmune diseases. Pathogenic, pathobiotic and commensal microorganisms contribute to disease progression in genetically susceptible hosts. Germ-free animals or defined-microbiota colonized animals are valuable tools for understanding microbial influences ...
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Modulating the microbiota [PDF]
Nature Chemical Biology, 2020 Nature Chemical Biology Mirella Bucci You can also search for this author in PubMed Google Scholar Correspondence to Mirella Bucci. Reprints and Permissions Bucci, M. Modulating the microbiota. Nat Chem Biol 16, 933 (2020). https://doi.org/10.1038/s41589-020-0635-5 Download citation Published: 18 August 2020 Issue Date: September 2020 DOI: https://doi ...
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Frontiers in Microbiology, 2020 Clostridioides difficile is a Gram-positive anaerobic intestinal pathogenic bacterium and the causative agent of antibiotic-associated diarrhea. C. difficile spore is a dormant state which acts as a vehicle of transmission and infection. In C.
Marjorie Pizarro-Guajardo +6 more
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Microbiota and faecal microbiota transplant
Microbiota in Health and Disease, 2021 As the range of disease states associated with the gut microbiome expands – and the mechanistic links between the gut microbiome and host physiology further deepens – so interest also grows in microbiome manipulation as medical therapy. In particular, bolstered by its established role in recurrent C.
Mullish, BH, Alexander, JL, Segal, JP
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Gut Microbes, 2022 The gut microbiota was emerging as critical regulatory elements in shaping the outcome of cancer immunotherapy. However, the underlying mechanisms by which the gut commensal species enhance antitumor immunity remain largely unexplored. Here, we show that
Shi-Long Zhang +8 more
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Frontiers in Microbiology, 2021 Serratia marcescens is a bacterial species widely found in the environment, which very efficiently colonizes mosquitoes. In this study, we isolated a red-pigmented S. marcescens strain from our mosquito colony (called S. marcescens VA).
Katy Heu +9 more
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Gut Microbiota-derived Bile Acids Promote Gamma-secretase Activity Through Interactions with Nicastrin Subunits [PDF]
arXiv, 2023 Alzheimer's disease (AD) has emerged as a progressively pervasive neurodegenerative disorder worldwide. Bile acids, synthesized in the liver and modified by the gut microbiota, play pivotal roles in diverse physiological processes, and their dysregulation in individuals with AD has been well-documented.
arxiv
Viruses and the Microbiota [PDF]
Annual Review of Virology, 2014 Every surface of the human body is colonized by a diverse microbial community called the microbiota, yet the impact of this community on viruses is unclear. Recent research has advanced our understanding of how microbiota influence viral infection. Microbiota inhibit infection by some viruses and promote infection by others.
Julie K. Pfeiffer +1 more
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