Tropomyosin antibody: the specific localization of tropomyosin in nonmuscle cells [PDF]
An antibody against purified chicken skeletal muscle tropomyosin is used in indirect immunofluorescence to visualize the localization of tropomyosin in a variety of nonmuscle cells.
Lazarides, Elias
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Molecular Model of the Microvillar Cytoskeleton and Organization of the Brush Border [PDF]
BACKGROUND. Brush border microvilli are ~1-µm long finger-like projections emanating from the apical surfaces of certain, specialized absorptive epithelial cells.
Brown, Jeffrey W., McKnight, C. James
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LIM Kinases in Osteosarcoma Development
Tumorigenesis is a long-term and multistage process that often leads to the formation of metastases. During this pathological course, two major events appear to be crucial: primary tumour growth and metastatic expansion. In this context, despite research
Régis Brion+5 more
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Comparative two-dimensional gel analysis and microsequencing identifies gelsolin as one of the most prominent downregulated markers of transformed human fibroblast and epithelial cells [PDF]
A systematic comparison of the protein synthesis patterns of cultured normal and transformed human fibroblasts and epithelial cells, using two-dimensional gel protein analysis combined with computerized imaging and data acquisition, identified a 90-kD ...
Bauw, Guy+4 more
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Characterization of Human Palladin, a Microfilament-associated Protein
Actin-containing microfilaments control cell shape, adhesion, and contraction. In striated muscle, α-actinin and other Z-disk proteins coordinate the organization and functions of actin filaments. In smooth muscle and nonmuscle cells, periodic structures termed dense bodies and dense regions, respectively, are thought to serve functions analogous to Z ...
Mikko Rönty+6 more
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Dephosphorylated but not phosphorylated microtubule associated protein MAP1B binds to microfilaments [PDF]
We have reported that purified native MAP1B interacts with microtubules but not with microfilaments [Pedrotti and Islam, Cell Motil. Cytoskel. (1995) 30, 301–309]. However, MAP1B can be phosphorylated at multiple sites by casein kinase II (CKII) and proline‐directed protein kinases (PDPK) and immunoblotting studies show that purified native MAP1B is ...
Barbara Pedrotti, Khalid Islam
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Plastins are a family of actin binding proteins (ABPs) known to cross-link actin microfilaments in mammalian cells, creating actin microfilament bundles necessary to confer cell polarity and cell shape.
Nan Li, Chris KC Wong, C Yan Cheng
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Despite the widespread recognition of adaptive radiation as a driver of speciation, the mechanisms by which natural selection generates new species are incompletely understood.
Feng Chen+10 more
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Gas2, a growth arrest-specific protein, is a component of the microfilament network system [PDF]
In this report we analyze the protein product of a growth arrest-specific gene, gas2, by means of an affinity-purified antibody raised against the protein produced in bacteria. The regulation of Gas2 biosynthesis reflects the pattern of mRNA expression (Schneider, C., R. King, and L. Philipson. 1988. Cell.
BRANCOLINI, Claudio+2 more
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Proteomic profiling of rabbit embryonic stem cells derived from parthenotes and fertilized embryos. [PDF]
Rabbit embryonic stem (rES) cells can be derived from various sources of embryos. However, understanding of the gene expression profile, which distincts embryonic stem (ES) cells from other cell types, is still extremely limited.
Payungsuk Intawicha+6 more
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