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The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Frontiers in Microbiology, 2022 Firespike leafroll-associated virus (FLRaV) is a major pathogen associated with firespike (Odontonema tubaeforme) leafroll disease. Phylogenetic analysis showed that FLRaV possesses typical traits of subgroup II members of ampeloviruses, but encodes two ...
Yaqin Wang +6 more
doaj +1 more source
An Essential Cytoskeletal Linker Protein Connecting Actin Microfilaments to Intermediate Filaments [PDF]
Cell, 1996 Typified by rapid degeneration of sensory neurons, dystonia musculorum mice have a defective BPAG1 gene, known to be expressed in epidermis. We report a neuronal splice form, BPAG1n, which localizes to sensory axons. Both isoforms have a coiled-coil rod, followed by a carboxy domain that associates with intermediate filaments.
Yang, Y. +5 more
openaire +4 more sources
Molecules, 2022 Gastric cancer is considered to be one of the most common causes of cancer death worldwide due to its high recurrence and metastasis rates. The molecule 23,24-Dihydrocucurbitacin E (DHCE) is a cucurbitacin-derived tetracyclic triterpenoid compound that ...
Huiping Liu +6 more
doaj +1 more source
Perturbing Microtubule Integrity Blocks AMP-Activated Protein Kinase-Induced Meiotic Resumption in Cultured Mouse Oocytes [PDF]
, 2012 The oocyte meiotic spindle is comprised of microtubules (MT) that bind chromatin and regulate both metaphase plate formation and karyokinesis during meiotic maturation; however, little information is known about their role in meiosis reinitiation.
Downs, Stephen, Ya, Ru
core +2 more sources
Differential regulation of actin microfilaments by human MICAL proteins
Journal of Cell Science, 2012 The Drosophila melanogaster MICAL protein is essential for the neuronal growth cone machinery that functions through plexin- and semaphorin-mediated axonal signaling. Drosophila MICAL is also involved in regulating myofilament organization and synaptic structures, and serves as an actin disassembly factor downstream of plexin-mediated axonal repulsion.
Naava Naslavsky +3 more
openaire +4 more sources
N-wasp Is Required For Structural Integrity Of The Blood-testis Barrier. [PDF]
, 2014 published_or_final_versio
Cheng, CY +10 more
core +5 more sources
eLife, 2019 Many bacterial pathogens can cause septicemia and spread from the bloodstream into internal organs. During leptospirosis, individuals are infected by contact with Leptospira-containing animal urine-contaminated water.
Yang Li +7 more
doaj +1 more source
A Microfilament-Eruption Mechanism for Solar Spicules [PDF]
Astrophysical Journal (Letters) 2016, 828, L9, 2016 Recent investigations indicate that solar coronal jets result from eruptions of small-scale chromospheric filaments, called minifilaments; that is, the jets are produced by scaled-down versions of typical-sized filament eruptions. We consider whether solar spicules might in turn be scaled-down versions of coronal jets, being driven by eruptions of ...
arxiv +1 more source
Suppression of Tumorigenicity in Breast Cancer Cells by the Microfilament Protein Profilin 1 [PDF]
The Journal of Experimental Medicine, 2000 Differential display screening was used to reveal differential gene expression between the tumorigenic breast cancer cell line CAL51 and nontumorigenic microcell hybrids obtained after transfer of human chromosome 17 into CAL51. The human profilin 1 (PFN1) gene was found overexpressed in the microcell hybrid clones compared with the parental line ...
Janke, J. +11 more
openaire +3 more sources