How does sleep deprivation affect the brain? We performed a meta‐analysis of publicly available transcriptional profiling datasets characterising the effects of sleep deprivation on cortical gene expression (n = 293 mice, 16,290 genes) and validated our results in an independent sample (n = 222 mice).
Cosette A. Rhoads +8 more
wiley +1 more source
Rooting Conifer Genetic Research: An Accessible and Efficient Transformation System
ABSTRACT Conifers serve as the cornerstone of global forest ecosystems, yet their genetic transformation faces notorious challenges. To overcome the intrinsic resistance of conifer adventitious roots to Agrobacterium/Rhizobium‐mediated transformation, we systematically and iteratively engineered the binary vector by introducing chimeric Ri plasmid ...
Jing‐Jing Li +10 more
wiley +1 more source
The role of the dorsomedial hypothalamus in the cardiogenic sympathetic reflex in the Sprague Dawley rat. [PDF]
Zahner MR, Hillard KJ, Chandley MC.
europepmc +1 more source
ABSTRACT Candidatus Liberibacter asiaticus (CLas), the causative agent of citrus Huanglongbing (HLB), is transmitted by Asian citrus psyllid, Diaphorina citri; however, the role of the insect's immune effectors in defending against CLas remains poorly understood. This study reveals that D.
Yu Du +9 more
wiley +1 more source
Lumbar spinal Shox2 interneurons receive monosynaptic excitatory input from the lateral paragigantocellular nucleus in mouse. [PDF]
Singh S, Yao L, Dougherty KJ.
europepmc +1 more source
A táplálékfelvétel szabályozása: Bombesin-típusú peptidek hatása a limbicus rendszerben [PDF]
Fekete Éva
core
Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation
Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson +7 more
wiley +1 more source
Automation in microinjection for zebrafish pericardial space with image-based motion control and batch agarose microplate. [PDF]
Lee HJ +5 more
europepmc +1 more source
Abstract figure legend We used an intersectional approach with recombinase‐expressing mice and adeno‐associated virus to map and modulate distinct nociceptive afferents in the vagal ganglia. TRPV1+P2X2+ neurons resided in the nodose ganglion (N), innervated the lungs (many projected into the alveoli) but not the trachea, and projected to the nucleus ...
Mayur J. Patil +11 more
wiley +1 more source
Functional State of Lampbrush Chromosomes in Early Vitellogenic Oocytes of Hibernating Frogs <i>Rana temporaria</i>. [PDF]
Ilicheva NV, Podgornaya OI.
europepmc +1 more source

