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Monitoring human health is of considerable significance in biomedicine. In particular, the ion concentrations in blood are important reference indicators related to many diseases.
Xinshuo Huang+7 more
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Microneedle-Mediated Transdermal Delivery of Biopharmaceuticals
Transdermal delivery provides numerous benefits over conventional routes of administration. However, this strategy is generally limited to a few molecules with specific physicochemical properties (low molecular weight, high potency, and moderate ...
Hiep X. Nguyen, Chien N. Nguyen
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Individually Modified Microneedle Array for Minimal Invasive Multi-Electrolyte Monitoring [PDF]
Electrolytes play crucial roles in regulating nerve and muscle functions. Currently, microneedle technology enables real-time electrolyte monitoring through minimally invasive methods.
Ketian Yu+7 more
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Transdermal microneedle patch for antioxidants release [PDF]
Polymer based microneedle transdermal drug delivery system fits the criterion for an efficient patient compliant drug delivery system of the future. Smart and controlled microneedle drug delivery systems remain an emerging research area.
Samuel Mugo, Scott Robertson, Weihao Lu
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Novel stereo DIC characterisation of microneedle and hypodermic needle insertion [PDF]
IntroductionMicroneedles are minimally invasive devices, designed for pain-free drug delivery. Until now, the degree of strain exerted on the skin during microneedle insertion, in comparison to gold standard hypodermic needles, has not been quantified ...
Megan McNamee+8 more
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Microneedle Sensors for Point‐of‐Care Diagnostics
Point‐of‐care (POC) has the capacity to support low‐cost, accurate and real‐time actionable diagnostic data. Microneedle sensors have received considerable attention as an emerging technique to evolve blood‐based diagnostics owing to their direct and ...
Yubing Hu+4 more
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Safety tests and clinical research on buccal and nasal microneedle swabs for genomic analysis
Conventional swabs have been used as a non-invasive method to obtain samples for DNA analysis from the buccal and the nasal mucosa. However, swabs may not always collect pure enough genetic material.
JeongHyeon Kim+9 more
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Microneedle Array Patches: Characterization and in -vitro Evaluation
Patch in transdermal drug delivery(TDDS) used to overcome the hypodermic drawback, but these patch also have absorption limitation for hydrophilic and macromolecule like peptide and DNA. So that micronized projection have the ability for skin penetration
Zainab A. Sadeq
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BackgroundA microneedle patch loaded with Atractylodes macrocephala Rhizoma water extract was prepared for the treatment of mammary gland hyperplasia.
Yang Ping+10 more
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Intratissue topical medication is important for the treatment of cutaneous, mucosal or splanchnic diseases. However, penetrating surface barriers to providing adequate and controllable drug delivery while guaranteeing adhesion in bodily fluids remains ...
Zhou Zhu+9 more
semanticscholar +1 more source