Results 1 to 10 of about 36,831 (386)

3D-assembled microneedle ion sensor-based wearable system for the transdermal monitoring of physiological ion fluctuations

open access: yesMicrosystems & Nanoengineering, 2023
Monitoring human health is of considerable significance in biomedicine. In particular, the ion concentrations in blood are important reference indicators related to many diseases.
Xinshuo Huang   +7 more
doaj   +2 more sources

Microneedle-Mediated Transdermal Delivery of Biopharmaceuticals

open access: yesPharmaceutics, 2023
Transdermal delivery provides numerous benefits over conventional routes of administration. However, this strategy is generally limited to a few molecules with specific physicochemical properties (low molecular weight, high potency, and moderate ...
Hiep X. Nguyen, Chien N. Nguyen
doaj   +2 more sources

Individually Modified Microneedle Array for Minimal Invasive Multi-Electrolyte Monitoring [PDF]

open access: yesBiosensors
Electrolytes play crucial roles in regulating nerve and muscle functions. Currently, microneedle technology enables real-time electrolyte monitoring through minimally invasive methods.
Ketian Yu   +7 more
doaj   +2 more sources

Transdermal microneedle patch for antioxidants release [PDF]

open access: yesDiscover Materials
Polymer based microneedle transdermal drug delivery system fits the criterion for an efficient patient compliant drug delivery system of the future. Smart and controlled microneedle drug delivery systems remain an emerging research area.
Samuel Mugo, Scott Robertson, Weihao Lu
doaj   +2 more sources

Novel stereo DIC characterisation of microneedle and hypodermic needle insertion [PDF]

open access: yesFrontiers in Bioengineering and Biotechnology
IntroductionMicroneedles are minimally invasive devices, designed for pain-free drug delivery. Until now, the degree of strain exerted on the skin during microneedle insertion, in comparison to gold standard hypodermic needles, has not been quantified ...
Megan McNamee   +8 more
doaj   +2 more sources

Microneedle Sensors for Point‐of‐Care Diagnostics

open access: yesAdvanced Science
Point‐of‐care (POC) has the capacity to support low‐cost, accurate and real‐time actionable diagnostic data. Microneedle sensors have received considerable attention as an emerging technique to evolve blood‐based diagnostics owing to their direct and ...
Yubing Hu   +4 more
doaj   +2 more sources

Safety tests and clinical research on buccal and nasal microneedle swabs for genomic analysis

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
Conventional swabs have been used as a non-invasive method to obtain samples for DNA analysis from the buccal and the nasal mucosa. However, swabs may not always collect pure enough genetic material.
JeongHyeon Kim   +9 more
doaj   +1 more source

Microneedle Array Patches: Characterization and in -vitro Evaluation

open access: yesIraqi Journal of Pharmaceutical Sciences, 2021
Patch in transdermal drug delivery(TDDS) used to overcome the hypodermic drawback, but these patch also have absorption limitation for hydrophilic and macromolecule like peptide and DNA. So that micronized projection have the ability for skin penetration
Zainab A. Sadeq
doaj   +1 more source

Construction of microneedle of Atractylodes macrocephala Rhizoma aqueous extract and effect on mammary gland hyperplasia based on intestinal flora

open access: yesFrontiers in Endocrinology, 2023
BackgroundA microneedle patch loaded with Atractylodes macrocephala Rhizoma water extract was prepared for the treatment of mammary gland hyperplasia.
Yang Ping   +10 more
doaj   +1 more source

Blue-ringed octopus-inspired microneedle patch for robust tissue surface adhesion and active injection drug delivery

open access: yesScience Advances, 2023
Intratissue topical medication is important for the treatment of cutaneous, mucosal or splanchnic diseases. However, penetrating surface barriers to providing adequate and controllable drug delivery while guaranteeing adhesion in bodily fluids remains ...
Zhou Zhu   +9 more
semanticscholar   +1 more source

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