Results 31 to 40 of about 18,959 (275)

Microneedle-Mediated Transdermal Delivery of Biopharmaceuticals

open access: yesPharmaceutics, 2023
Transdermal delivery provides numerous benefits over conventional routes of administration. However, this strategy is generally limited to a few molecules with specific physicochemical properties (low molecular weight, high potency, and moderate ...
Hiep X. Nguyen, Chien N. Nguyen
doaj   +1 more source

MICRONEEDLE STRUCTURE DESIGN AND OPTIMIZATION USING GENETIC ALGORITHM [PDF]

open access: yesJournal of Engineering Science and Technology, 2015
This paper presents a Genetic Algorithm (GA) based microneedle design and analysis. GA is an evolutionary optimization technique that mimics the natural biological evolution.
N. A. ISMAIL   +3 more
doaj  

Multifunctional polysaccharide composited microneedle for oral ulcers healing

open access: yesMaterials Today Bio, 2023
Oral ulcers have periodicity and recurrence, and the etiology and causative mechanisms remain unclear; therefore, it is difficult to treat oral ulcers effectively.
Yiyu Zeng   +6 more
doaj   +1 more source

Method of coating microneedle devices

open access: yes, 2013
Microneedle devices are spray coated by nozzles which jet dispense dots onto the individual needles of a microneedle device from a spray nozzle which is angled with respect to the plane of the microneedle device.
Douroumis, Dionysios
core   +4 more sources

MXene-Integrated Microneedle Patches with Innate Molecule Encapsulation for Wound Healing

open access: yesResearch, 2021
Wound healing is a complex physiological process that involves coordinated phases such as inflammation and neovascularization. Attempts to promote the healing process tend to construct an effective delivery system based on different drugs and materials ...
Lingyu Sun   +5 more
doaj   +1 more source

Fabrication of Microneedles

open access: yes2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, 2007
This research paper was performed to study and utilizes two kinds of materials which match with two different fabrications in order to design an ideal shape of microneedles. The technology employs the polymer microneedles and the silicon microneedles with the height of 236 mum and 350 mum respectively.
Yu-Tang Chen   +3 more
openaire   +2 more sources

Effect of dissolving-microneedle-patch loaded OVA on splenocytes and lymphocytes proliferation and cytokine production in mice.

open access: yes, 2019
Effect of dissolving-microneedle-patch loaded OVA on splenocytes and lymphocytes proliferation and cytokine production in mice.
Kyung-Yun Kang (7140260)   +10 more
core   +1 more source

Immunization by dissolving-microneedle-patch loaded OVA induces OVA-specific CTL activity and cytokine levels (IFN-ɣ).

open access: yes, 2019
Immunization by dissolving-microneedle-patch loaded OVA induces OVA-specific CTL activity and cytokine levels (IFN-ɣ).
Kyung-Yun Kang (7140260)   +10 more
core   +1 more source

Microneedles

open access: yesBiomaterials Science, 2023
Wound management is a serious concern worldwide, inflicting a huge social and economic burden on patients and healthcare systems, and research into efficient wound-management measures is crucial. Although advances have been made in traditional wound dressings for wound management to date, the complicated environment near the wound leads to inadequate ...
Zhao, Ze Qiang   +7 more
  +5 more sources

Effect of dissolving-microneedle-patch loaded OVA on splenocytes and lymphocytes proliferation in mice.

open access: yes, 2019
The mice (n = 4/group) were immunized either using the dissolving-microneedle-patch or dissolving-microneedle-patch loaded OVA. The splenocytes and lymphocytes of each group were re-stimulated with OVA 7 days after the last immunization.
Kyung-Yun Kang (7140260)   +10 more
core   +1 more source

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