Results 41 to 50 of about 15,286 (297)
Microneedle-based drug and vaccine delivery via nanoporous microneedle arrays [PDF]
, 2015 In the literature, several types of microneedles have been extensively described. However, porous microneedle arrays only received minimal attention. Hence, only little is known about drug delivery via these microneedles.
Luttge, R. +22 more
core +1 more source
, 2019 Immunization by dissolving-microneedle-patch loaded OVA induces OVA-specific CTL activity and cytokine levels (IFN-ɣ).
Kyung-Yun Kang (7140260) +10 more
core +1 more source
Separable arrowhead microneedles [PDF]
Journal of Controlled Release, 2011 Hypodermic needles cause pain and bleeding, produce biohazardous sharp waste and require trained personnel. To address these issues, we introduce separable arrowhead microneedles that rapidly and painlessly deliver drugs and vaccines to the skin. These needles are featured by micron-size sharp tips mounted on blunt shafts.
Leonard Y, Chu, Mark R, Prausnitz
openaire +2 more sources
Effect of dissolving-microneedle-patch loaded OVA on OVA-specific T cell response in mice.
, 2019 The mice (n = 4/group) were immunized either using the dissolving-microneedle-patch or dissolving-microneedle-patch loaded OVA. The splenocytes of each group were re-stimulated with OVA 7 days after the last immunization and CD4+, and CD8+ T cells were ...
Kyung-Yun Kang (7140260) +10 more
core +1 more source
Advanced Healthcare Materials, EarlyView.PolyGraph, a flexible graphene‐polycaprolactone nanocomposite, unites conductivity, biocompatibility, and processability for next‐generation neural interfaces. Fabricated into microneedle arrays with ultra‐flexible backings, PolyGraph enables bidirectional neuronal recording and stimulation in brain tissue, advancing brain‐computer interface (BCI) and ...
Jack Maughan +12 more
wiley +1 more source
, 2019 Diabetic ketoacidosis (DKA), a severe complication of diabetes mellitus with potentially fatal consequences, is characterized by hyperglycemia and metabolic acidosis due to the accumulation of ketone bodies, which requires people with diabetes to monitor
Patrick P. Mercier (2887019) +9 more
core +1 more source
Advanced Healthcare Materials, EarlyView.This review examines how in vitro electrical and mechanical stimulation modulates wound healing in fibroblasts and keratinocytes. Analyzing over 560 experimental data points, we relate stimulation parameters to proliferation and migration outcomes, evaluate platform designs, and highlight the need for multi‐parameter optimization to advance targeted ...
Matthew K. Burgess +3 more
wiley +1 more source
Chinese Medicine and Natural ProductsObjective Our objective was to assess the effectiveness and safety of microneedle by comparing microneedle plus 5% topical minoxidil treatment and microneedle alone to 5% topical minoxidil.
Chunyan Xu +3 more
doaj +1 more source
Transdermal Polymeric Microneedle Sensing Platform for Fentanyl Detection in Biofluid
Biosensors, 2022 Opioid drugs are extremely potent synthetic analytes, and their abuse is common around the world. Hence, a rapid and point-of-need device is necessary to assess the presence of this compound in body fluid so that a timely countermeasure can be provided ...
Pratik Joshi +4 more
doaj +1 more source
Microvascular effects of microneedle application
, 2021 Background The efficiency of transdermal drug delivery may be increased by pretreating the skin with microneedles, but distinct effects of microneedles and the microneedle-enhanced delivery of vasoactive drugs on the skin microvasculature are still not ...
Tesselaar, Erik +14 more
core +1 more source