Results 51 to 60 of about 18,959 (275)

Bioinspired Rotation Microneedles for Accurate Transdermal Positioning and Ultraminimal-Invasive Biomarker Detection with Mechanical Robustness

open access: yesResearch, 2022
Microneedle permits transdermal biosensing and drug delivery with minor pain. However, accurate microneedle transdermal positioning with minimal skin deformation remains a significant technical challenge due to inhomogeneous skin topology and ...
Yilin Cai   +6 more
doaj   +1 more source

Transdermal Polymeric Microneedle Sensing Platform for Fentanyl Detection in Biofluid

open access: yesBiosensors, 2022
Opioid drugs are extremely potent synthetic analytes, and their abuse is common around the world. Hence, a rapid and point-of-need device is necessary to assess the presence of this compound in body fluid so that a timely countermeasure can be provided ...
Pratik Joshi   +4 more
doaj   +1 more source

Effect of dissolving-microneedle-patch loaded OVA on OVA-specific CD4+/CD8+ T cell response in mice.

open access: yes, 2019
Effect of dissolving-microneedle-patch loaded OVA on OVA-specific CD4+/CD8+ T cell response in mice.
Kyung-Yun Kang (7140260)   +10 more
core   +1 more source

3D Printed Polypyrrole Microneedle Arrays for Electronically Controlled Transdural Drug Release [PDF]

open access: yes, 2020
Thesis (Master's)--University of Washington, 2020The secondary injury causes further damage to neural cells, due to mechanisms of inflammation and cytotoxicity.
Huang, Joyce
core  

Spatially Configurable Conformal Sensor Integration on an Ultra‐Fine Metallic Needle for Minimally Invasive Deep‐Tissue Oxygen Monitoring

open access: yesAdvanced Materials Technologies, EarlyView.
A multi‐point oxygen‐sensing ultra‐fine needle (MO‐UFN) is developed by conformally integrating a lithographically patterned flexible electrochemical sensor array onto a clinical acupuncture needle. The platform preserves an approximately 0.3 mm diameter while enabling spatially resolved oxygen profiling along the insertion pathway.
Yeju Seo   +9 more
wiley   +1 more source

Wearable microneedle-based colorimetric and fluorescence sensing for transdermal diagnostics

open access: yesTalanta Open, 2023
Interstitial fluid is a readily accessible source of biomarkers for various diseases, providing a less invasive and more convenient option than traditional blood or tissue sampling methods.
Jiraporn Leanpolchareanchai   +1 more
doaj   +1 more source

Microneedle-Based Detection of Ketone Bodies along with Glucose and Lactate: Toward Real-Time Continuous Interstitial Fluid Monitoring of Diabetic Ketosis and Ketoacidosis

open access: yes, 2019
Diabetic ketoacidosis (DKA), a severe complication of diabetes mellitus with potentially fatal consequences, is characterized by hyperglycemia and metabolic acidosis due to the accumulation of ketone bodies, which requires people with diabetes to monitor
Patrick P. Mercier (2887019)   +9 more
core   +1 more source

Recent Advances in Light‐Addressable Electrochemistry for Spatially Resolved Applications

open access: yesAdvanced Materials Technologies, EarlyView.
This comprehensive review highlights light‐addressable electrochemistry as a powerful tool that uses light to control localized chemical reactions on unstructured semiconductor surfaces. The work evaluates advanced strategies to optimize electrode materials for enhanced spatial resolution and stability. Furthermore, it showcases diverse applications in
Nhi Trang Vo   +2 more
wiley   +1 more source

Effect of dissolving-microneedle-patch loaded OVA on OVA-specific T cell response in mice.

open access: yes, 2019
The mice (n = 4/group) were immunized either using the dissolving-microneedle-patch or dissolving-microneedle-patch loaded OVA. The splenocytes of each group were re-stimulated with OVA 7 days after the last immunization and CD4+, and CD8+ T cells were ...
Kyung-Yun Kang (7140260)   +10 more
core   +1 more source

Self‐Sealing Microneedles Improve Precision and Reduce Reflux in Subretinal Cell Transplantation

open access: yesAdvanced Materials Technologies, EarlyView.
Ultrafine 49G microneedles enable subretinal delivery of induced pluripotent stem cell‐derived retinal pigment epithelial cells through a 50 µm outer diameter tip. Compared with conventional 38G microcannulas, these microneedles reduce cell suspension reflux in a rabbit model, highlighting the potential of microinvasive delivery instruments to improve ...
Jared Ching   +9 more
wiley   +1 more source

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