Results 11 to 20 of about 18,959 (275)

An overview of microneedle applications, materials, and fabrication methods [PDF]

Beilstein Journal of Nanotechnology, 2021
Microneedle-based microdevices promise to expand the scope for delivery of vaccines and therapeutic agents through the skin and withdrawing biofluids for point-of-care diagnostics – so-called theranostics.
Zahra Faraji Rad, Philip D. Prewett, Graham J. Davies   +2 more
doaj   +2 more sources

Microneedle Radiofrequency

Facial Plastic Surgery Clinics of North America, 2020
Microneedle radiofrequency (RF) is a breakthrough in targeting skin laxity and rhytids that provides direct in situ delivery, impedance measurements, temperature measurements, energy delivery controls, and targeting of various skin depths to achieve desired clinical outcomes.
Alexiades, M.
core   +5 more sources

Current advancements in microneedle technology for therapeutic and biomedical applications

Sensors International
Microneedle technology has gained large interest as an innovative biomedical device to deliver molecules to the targeted site through the skin layers. Microneedle consists of microscale needle with a specific length about 0.1–1 mm.
Olivia Sen, Poulami Poddar, Poulami Sarkar, Sanchita Das, Sreejan Manna   +4 more
doaj   +2 more sources

Microneedle-assisted permeation of lidocaine carboxymethylcellulose with gelatine co-polymer hydrogel [PDF]

, 2014
Purpose Lidocaine hydrochloride (LidH) was formulated in sodium carboxymethyl cellulose/ gelatine (NaCMC/GEL) hydrogel and a ‘poke and patch’ microneedle delivery method was used to enhance permeation flux of LidH.
Atul Nayak (1253046), Diganta Das (1254000), Goran Vladisavljevic (1253448)   +2 more
core   +5 more sources

Construction of microneedle of Atractylodes macrocephala Rhizoma aqueous extract and effect on mammary gland hyperplasia based on intestinal flora

Frontiers in Endocrinology, 2023
BackgroundA microneedle patch loaded with Atractylodes macrocephala Rhizoma water extract was prepared for the treatment of mammary gland hyperplasia.
Yang Ping, Qi Gao, Changxu Li, Yan Wang, Yuliang Wang, Shuo Li, Mingjing Qiu, Linqian Zhang, Ailing Tu, Yu Tian, Hong Zhao   +10 more
doaj   +1 more source

Layer-Specific Dermal and Subcutaneous Delivery via Modular LNP-Hydrogel-Integrated Threaded Microneedles. [PDF]

Adv Sci (Weinh)
Guided by spatial transcriptomics and clinical validation, a threaded microneedle platform enables precise layer‐specific delivery across the dermis and subcutaneous tissue. By addressing distinct pathogenic remodeling in different skin layers, this strategy coordinates compartment‐specific intervention, restores tissue architecture, and offers a ...
Xie F, Zhang Y, Ling S, Huang Y, Wei Y, Fu R, He J, Liu B, Zhou L, Huo K, Wang Y, Li Q, Du Y, Cui W, Xie Y.   +14 more
europepmc   +2 more sources

3D-assembled microneedle ion sensor-based wearable system for the transdermal monitoring of physiological ion fluctuations

Microsystems & Nanoengineering, 2023
Monitoring human health is of considerable significance in biomedicine. In particular, the ion concentrations in blood are important reference indicators related to many diseases.
Xinshuo Huang, Shantao Zheng, Baoming Liang, Mengyi He, Feifei Wu, Jingbo Yang, Hui-jiuan Chen, Xi Xie   +7 more
doaj   +1 more source

Determination of Transdermal Rate of Metallic Microneedle Array through an Impedance Measurements-Based Numerical Check Screening Algorithm

Micromachines, 2022
Microneedle systems have been widely used in health monitoring, painless drug delivery, and medical cosmetology. Although many studies on microneedle materials, structures, and applications have been conducted, the applications of microneedles often ...
Jingshan Mo, Junqing Liu, Shuang Huang, Baoming Liang, Xinshuo Huang, Cheng Yang, Meiwan Chen, Jing Liu, Tong Zhang, Xi Xie, Jun Guo, Fanmao Liu, Hui-Jiuan Chen   +12 more
doaj   +1 more source

Biodegradable microneedle patch for delivery of meloxicam for managing pain in cattle.

PLoS ONE, 2022
Microneedle patches are a promising source for transdermal diffusion of macromolecules and are designed to painlessly penetrate the skin. In this study, a biodegradable chitosan microneedle patch to deliver meloxicam for managing pain in cattle was ...
David A Castilla-Casadiego, Katherine A Miranda-Muñoz, Jesse L Roberts, Anne D Crowell, David Gonzalez-Nino, Dipankar Choudhury, Frank O Aparicio-Solis, Shannon L Servoss, Adrianne M Rosales, Gary Prinz, Min Zou, Yuntao Zhang, Johann F Coetzee, Lauren F Greenlee, Jeremy Powell, Jorge Almodovar   +15 more
doaj   +1 more source

Continuous Glucose Monitoring System Based on Percutaneous Microneedle Array

Micromachines, 2022
A continuous blood glucose monitoring system (CGMS) which include a microneedle-array blood glucose sensor, a circuit module, and a transmission module placed in a wearable device is developed in this research.
Ming-Nan Chien, Yu-Jen Chen, Chin-Han Bai, Jung-Tung Huang   +3 more
doaj   +1 more source