Results 91 to 100 of about 36,831 (386)
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.Islatravir‐loaded dissolving microarray patches (MAPs) provide a minimally invasive, long‐acting solution for HIV‐1 prevention and treatment. In rats, sustained islatravir delivery lasts up to three months, while in minipigs, efficacious plasma levels are detected for six days.
Qonita Kurnia Anjani +11 more
wiley +1 more source
Force-induced recruitment of cten along keratin network in epithelial cells. [PDF]
, 2019 The cytoskeleton provides structural integrity to cells and serves as a key component in mechanotransduction. Tensins are thought to provide a force-bearing linkage between integrins and the actin cytoskeleton; yet, direct evidence of tensin's role in ...
Cheah, Joleen S +4 more
core
Smart Polymeric 3D Microscaffolds Hosting Spheroids for Neuronal Research via Quantum Metrology
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.Development of a platform consisting of 3D microscaffolds supporting 3D embryoid bodies for neuronal research. The polymeric scaffolds enable directed growth of neurites. This study shows nanodiamond‐based quantum sensors graft onto the polymer material, enabling quantum metrology experiments within the 3D neuronal model and thereby providing a ...
Beatriz N. L. Costa +5 more
wiley +1 more source
Pharmaceutics, 2014 This study evaluated the feasibility of coating formulated recombinant human growth hormone (rhGH) on a titanium microneedle transdermal delivery system, Zosano Pharma (ZP)-hGH, and assessed preclinical patch delivery performance.
Mahmoud Ameri +7 more
doaj +1 more source
, 2022 The most frequent modalities for transdermal medication administration include hypodermic needles, topical creams, and transdermal patches. Because the stratum corneum layer of the skin functions as a barrier for molecules, only a few molecules reach the site of action, most therapeutic medications have a limited effect. This page discusses the various
openaire +1 more source
Microvascular effects of microneedle application
Skin Research and Technology, 2020 AbstractBackgroundThe efficiency of transdermal drug delivery may be increased by pretreating the skin with microneedles, but distinct effects of microneedles and the microneedle‐enhanced delivery of vasoactive drugs on the skin microvasculature are still not well investigated.Materials and MethodsIn eight healthy human subjects, we measured the ...
Johannes Hackethal +4 more
openaire +5 more sources
Vaccine delivery with microneedle skin patches in nonhuman primates [PDF]
, 2013 Transcutaneous drug delivery from planar skin patches is effective for small-molecule drugs and skin-permeable vaccine adjuvants. However, to achieve efficient delivery of vaccines and other macromolecular therapeutics into the skin, penetration of the ...
Adrienne V Li +28 more
core +3 more sources
Advanced Healthcare Materials, EarlyView.This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto +2 more
wiley +1 more source
Transdermal electroosmotic flow generated by a porous microneedle array patch
Nature Communications, 2021 A microneedle array is an attractive option for a minimally invasive means to break through the skin barrier for efficient transdermal drug delivery.
Shinya Kusama +6 more
semanticscholar +1 more source
Modern concepts in non-surgical esthetics; a review [PDF]
, 2019 New non-surgical esthetics is the most dynamic field in contemporary medicine. At the same time, it is greatly influenced by our contemporary society. This paper reviews modern methods used in non-surgical esthetics, especially in Romania.
Andronache, Liliana F +7 more
core +3 more sources