Results 51 to 60 of about 36,831 (386)

Determination of parameters for successful spray coating of silicon microneedle arrays [PDF]

, 2011
Coated microneedle patches have demonstrated potential for effective, minimally invasive, drug and vaccine delivery. To facilitate cost-effective, industrial-scale production of coated microneedle patches, a continuous coating method which utilises ...
Crean, Abina M., McGrath, Marie G., Moore, Anne C., O'Mahony, Conor, Oliveira, Jorge C., Vrdoljak, Anto   +5 more
core   +1 more source

Substrate Deformation Predicts Neuronal Growth Cone Advance [PDF]

, 1977
Although pulling forces have been observed in axonal growth for several decades, their underlying mechanisms, absolute magnitudes, and exact roles are not well understood.
Athamneh, Ahmad I.M., Cartagena-Rivera, Alexander X., Raman, Arvind, Suter, Daniel M.   +3 more
core   +1 more source

MICRONEEDLE STRUCTURE DESIGN AND OPTIMIZATION USING GENETIC ALGORITHM [PDF]

Journal of Engineering Science and Technology, 2015
This paper presents a Genetic Algorithm (GA) based microneedle design and analysis. GA is an evolutionary optimization technique that mimics the natural biological evolution.
N. A. ISMAIL, S. C. NEOH, N. SABANI, B. N. TAIB   +3 more
doaj  

Flexible and Stretchable Microneedle Patches with Integrated Rigid Stainless Steel Microneedles for Transdermal Biointerfacing. [PDF]

PLoS ONE, 2016
This paper demonstrates flexible and stretchable microneedle patches that combine soft and flexible base substrates with hard and sharp stainless steel microneedles.
Mina Rajabi, Niclas Roxhed, Reza Zandi Shafagh, Tommy Haraldson, Andreas Christin Fischer, Wouter van der Wijngaart, Göran Stemme, Frank Niklaus   +7 more
doaj   +1 more source

Skin preparation–free, stretchable microneedle adhesive patches for reliable electrophysiological sensing and exoskeleton robot control

Science Advances
High-fidelity and comfortable recording of electrophysiological (EP) signals with on-the-fly setup is essential for health care and human-machine interfaces (HMIs).
Heesoo Kim, Juhyun Lee, Ung Heo, Dhileep Kumar Jayashankar, K. Agno, Yeji Kim, Choong Yeon Kim, Youngjun Oh, S. Byun, Bohyung Choi, Hwayeong Jeong, W. Yeo, Zhuo Li, Seongjun Park, Jianliang Xiao, Jung Kim, Jae‐Woong Jeong   +16 more
semanticscholar   +1 more source

Microfluidics for Advanced Drug Delivery Systems. [PDF]

, 2015
Considerable efforts have been devoted towards developing effective drug delivery methods. Microfluidic systems, with their capability for precise handling and transport of small liquid quantities, have emerged as a promising platform for designing ...
Dokmeci, Mehmet R, Ghaemmaghami, Amir, Khademshosseini, Ali, Riahi, Reza, Shaegh, Seyed Ali Mousavi, Tamayol, Ali   +5 more
core   +1 more source

Separable arrowhead microneedles [PDF]

Journal of Controlled Release, 2011
Hypodermic needles cause pain and bleeding, produce biohazardous sharp waste and require trained personnel. To address these issues, we introduce separable arrowhead microneedles that rapidly and painlessly deliver drugs and vaccines to the skin. These needles are featured by micron-size sharp tips mounted on blunt shafts.
Leonard Y. Chu, Mark R. Prausnitz
openaire   +3 more sources

Bioinspired Rotation Microneedles for Accurate Transdermal Positioning and Ultraminimal-Invasive Biomarker Detection with Mechanical Robustness

Research, 2022
Microneedle permits transdermal biosensing and drug delivery with minor pain. However, accurate microneedle transdermal positioning with minimal skin deformation remains a significant technical challenge due to inhomogeneous skin topology and ...
Yilin Cai, Shiyi Huang, Zhinan Zhang, Jiazheng Zhang, Xingyue Zhu, Xiaoxiang Chen, Xianting Ding   +6 more
doaj   +1 more source

Programmable CRISPR-Cas9 microneedle patch for long-term capture and real-time monitoring of universal cell-free DNA

Nature Communications, 2022
Recent advances in biointerfaces have led to the development of wearable devices that can provide insights into personal health. As wearable modules, microneedles can extract analytes of interest from interstitial fluid in a minimally invasive fashion ...
Bin Yang, J. Kong, Xueen Fang
semanticscholar   +1 more source

Microneedling with dermaroller

Journal of Cutaneous and Aesthetic Surgery, 2009
Microneedling with dermaroller is a new treatment modality for the treatment of scars, especially acne scars, stretch marks, wrinkles, and for facial rejuvenation. It is a simple and relatively cheap modality that also can be used for transdermal drug delivery.
openaire   +3 more sources