Results 121 to 130 of about 412 (149)
Some of the next articles are maybe not open access.
Clinical Efficacy of Micronized Purified Flavonoid Fraction: An Overview
Journal of Vascular Research, 1999Flavonoids are widely used for the treatment of chronic venous insufficiency (CVI). In clinical trials, micronized purified flavonoid fraction (MPFF, 450 mg diosmin plus 50 mg hesperidin, Daflon 500 mg) has demonstrated its activity in CVI by improving venous tone and vein elasticity assessed by plethysmography.
openaire +2 more sources
Clinical Efficacy of Micronized Purified Flavonoid Fraction (MPFF) in Edema
Angiology, 2000Swelling is one of the most frequent complaints of patients in daily clinical practice; leg edema is its objective confirmation. It can be associated with several diseases. Micronized purified flavonoid fraction (MPFF) is a phlebotropic drug commonly used to treat the signs and symptoms associated with chronic venous insufficiency (CVI).
openaire +2 more sources
Reactive Oxygen Species, 2020
Micronized purified flavonoid fraction (MPFF; Daflon®) containing 90% diosmin and 10% hesperidin is a vasoactive drug used for the treatment of chronic venous insufficiency and hemorrhoids. The aim of this study was to examine the effect of MPFF on the development of brain oxidative stress and neuronal damage induced in the rat by systemic rotenone ...
Omar Abdel-Salam +3 more
openaire +1 more source
Micronized purified flavonoid fraction (MPFF; Daflon®) containing 90% diosmin and 10% hesperidin is a vasoactive drug used for the treatment of chronic venous insufficiency and hemorrhoids. The aim of this study was to examine the effect of MPFF on the development of brain oxidative stress and neuronal damage induced in the rat by systemic rotenone ...
Omar Abdel-Salam +3 more
openaire +1 more source
Protective Effects of Micronized Purified Flavonoid Fraction (MPFF) on a Novel Experimental Model of Chronic Venous Hypertension [PDF]
European Journal of Vascular and Endovascular Surgery, 2018 To assess protective effects of micronized purified flavonoid fraction (MPFF) on microcirculation in an original chronic model of hind limb venous hypertension with low blood flow in small animals.Vein ligatures were performed on male hamsters, as follows: A-right femoral vein; A + B-right femoral vein and its right branch; A + C-right femoral vein and
Maria das Graças Coelho de Souza +2 more
exaly +3 more sources
International Angiology, 2018
Sclerotherapy is the treatment of choice for telangiectasias. The aim of this study was to investigate the systemic and local inflammatory response after sclerotherapy in women with chronic venous disease (CVD) and to assess the effects of micronized purified flavonoid fraction (MPFF) in combination with sclerotherapy on markers of inflammation and ...
Vadim Y, Bogachev +2 more
openaire +2 more sources
Sclerotherapy is the treatment of choice for telangiectasias. The aim of this study was to investigate the systemic and local inflammatory response after sclerotherapy in women with chronic venous disease (CVD) and to assess the effects of micronized purified flavonoid fraction (MPFF) in combination with sclerotherapy on markers of inflammation and ...
Vadim Y, Bogachev +2 more
openaire +2 more sources
Transplantation Proceedings, 2015
Flavonoids have been subjected to considerable investigation because of its antioxidant and anti-inflammatory properties. However, there is no previously reported study about its effect on hepatic ischemia/reperfusion (I/R). We investigated the effects of micronized purified flavonoid fraction (MPFF) on hepatic I/R injury in rats.Thirty rats were ...
F, Yildiz +4 more
openaire +2 more sources
Flavonoids have been subjected to considerable investigation because of its antioxidant and anti-inflammatory properties. However, there is no previously reported study about its effect on hepatic ischemia/reperfusion (I/R). We investigated the effects of micronized purified flavonoid fraction (MPFF) on hepatic I/R injury in rats.Thirty rats were ...
F, Yildiz +4 more
openaire +2 more sources
Journal of Vascular Research, 1999
Ischemia and reperfusion (I/R) induces neutrophil infiltration in skeletal muscle that is localized to the ischemic region. To transmigrate at ischemic regions, granulocytes must first arrest in the postcapillary venular segment of the microcirculation.
R J, Korthuis, D C, Gute
openaire +2 more sources
Ischemia and reperfusion (I/R) induces neutrophil infiltration in skeletal muscle that is localized to the ischemic region. To transmigrate at ischemic regions, granulocytes must first arrest in the postcapillary venular segment of the microcirculation.
R J, Korthuis, D C, Gute
openaire +2 more sources
Angiology and vascular surgery, 2019
Analysed herein is the experience with micronized purified flavonoid fraction (MPFF) in treatment of geriatric patients with decompensated forms of chronic venous diseases. A total of 218 geriatric patients were examined and treated. Of these, 132 patients had trophic disorders (C4-C6 class), including 40 patients found to have venous trophic ulcers ...
Iu M, Stoĭko +3 more
openaire +2 more sources
Analysed herein is the experience with micronized purified flavonoid fraction (MPFF) in treatment of geriatric patients with decompensated forms of chronic venous diseases. A total of 218 geriatric patients were examined and treated. Of these, 132 patients had trophic disorders (C4-C6 class), including 40 patients found to have venous trophic ulcers ...
Iu M, Stoĭko +3 more
openaire +2 more sources
Microcirculation, 2000
ABSTRACTThe standard treatments for venous diseases of the lower limb include compression bandaging and stockings as well as surgical removal of varicose veins. There is a number of conditions in which these conventional treatments are ineffective, particularly in the management of leg ulceration.
openaire +2 more sources
ABSTRACTThe standard treatments for venous diseases of the lower limb include compression bandaging and stockings as well as surgical removal of varicose veins. There is a number of conditions in which these conventional treatments are ineffective, particularly in the management of leg ulceration.
openaire +2 more sources
Anti-Inflammatory Actions of a Micronized, Purified Flavonoid Fraction in Ischemia/Reperfusion
2002It is now recognized that reperfusion after a prolonged period of reduced or absent blood flow, although necessary to salvage ischemic tissue, initiates a complex series of deleterious reactions which ultimately induce the same effects as ischemia per se, i.e., cell injury and necrosis.
Ronald J. Korthuis, Dean C. Gute
openaire +1 more source