Results 131 to 140 of about 412 (149)

The Effect of Micronized Purified Flavonoid Fraction on the Prevention of Testicular Pathologies in Adolescent Rats with Experimentally Induced Varicocele

Journal of Urology, 2012
We investigated the effect of micronized purified flavonoid fraction on the prevention of testicular pathologies following varicocele induction.A total of 66 adolescent (6-week-old) male Wistar rats were included in study. Rats were divided into 7 groups, including group 1--control, group 2--sham operation, group 3--left varicocele induced, group 4 ...
Osman Ergun, Hakan Darici, Taylan Oksay
exaly   +6 more sources

[Micronized purified flavonoid fraction in treatment of pelvic varicose veins].

Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery, 2012
Presented herein are the results of studying efficacy of micronized purified flavonoid fraction (MPFF) in treatment of pelvic varicose veins (PVV) using reference ray-tracing methods of study. We examined a total of 85 patients with PVV. Of these, 65 subjects were found to have isolated dilatation of pelvic venous plexuses (study group), and 20 were ...
S G, Gavrilov, A V, Karalkin, E P, Moskalenko, E S, Beliaeva, A M, Ianina, A I, Kirienko   +5 more
openaire   +1 more source

Benefit of a 2-Month Treatment with a Micronized, Purified Flavonoidic Fraction on Venous Ulcer Healing

International Journal of Microcirculation, 2008
Objective: To assess the efficacy of a micronized purified flavonoid fraction (Daflon 500 mg = Dios) in venous leg ulcer healing, in addition to compression therapy and standardized local care. Design: Double-blind, multicentre, randomized, parallel groups, controlled versus placebo trial; stratification according to ulcer size. Subjects: 107 patients,
J.-J. Guilhou, F. Février, C. Debure, D. Dubeaux, M.-N. Gillet-Terver, B. Guillot, H. Levesque, L. Marzin, J. Mignot, P. Ouvry, G. Pillion, H. Van Landuyt, F. Zuccarelli, A.N. Nicolaïdes   +13 more
openaire   +1 more source

Effectiveness and safety of micronized purified flavonoid fraction for the treatment of concomitant varicose veins of the pelvis and lower extremities

Current Medical Research and Opinion, 2018
Concomitant varicose veins of the pelvis (VVP) and lower extremities (VVLE) frequently coexist. This study evaluated the effectiveness and safety of micronized purified flavonoid fraction (MPFF) in the treatment of patients with both conditions.Female outpatients with concomitant VVP and VVLE received MPFF 1000 mg once daily for 2 months (Group 1), or ...
Sergey G. Gavrilov, Yekaterina P. Moskalenko, Anatoly V. Karalkin   +2 more
openaire   +2 more sources

Purified Micronized Flavonoid Fraction Ameliorates the Injury of Spleen and Ileum Secondary to Hepatic Ischemia–Reperfusion in Rats

Digestive Diseases and Sciences, 2009
Flavonoids have been subjected to considerable investigations due to their antioxidant and anti-inflammatory properties. Yet the effects of flavonoids on the ileum and spleen against hepatic ischemia-reperfusion injury have so far not been addressed.We aimed to investigate whether micronized purified flavonoid fraction (MPFF) protects the ileum and ...
Fahrettin, Yildiz, Alpaslan, Terzi, Sacit, Coban, Muharrem, Bitiren, Hakim, Celik, Nurten, Aksoy, Mustafa Kemal, Ozdogan, Hale, Cakir   +7 more
openaire   +2 more sources

Lymphatic regeneration across an incisional wound: Inhibition by dexamethasone and aspirin, and acceleration by a micronized purified flavonoid fraction

European Journal of Pharmacology, 2006
Although the antiinflammatory and antiangiogenic properties of dexamethasone and acetylsalicylic acid have been studied extensively, their effects on lymphangiogenesis in regenerating tissues remain mostly unknown. We studied in rats the pharmacological modulation and the effect of a remote inflammatory stimulus on the lymphatic regeneration upon ...
Karin Vicente, Greco, Pedro Fernandes, Lara, Ricardo Martins, Oliveira-Filho, Rômulo Vicente, Greco, Lia Siguemi, Sudo-Hayashi   +4 more
exaly   +3 more sources

Anti-inflammatory actions of a micronized, purified flavonoid fraction in ischemia/reperfusion.

Advances in experimental medicine and biology, 2003
It is now recognized that reperfusion after a prolonged period of reduced or absent blood flow, although necessary to salvage ischemic tissue, initiates a complex series of deleterious reactions which ultimately induce the same effects as ischemia per se, i.e., cell injury and necrosis.
Ronald J, Korthui, Dean C, Gute
openaire   +1 more source

Efficacy of Micronized Purified Flavonoid Fraction in the Posthemorrhoidectomy Period Trial: Open-Label Randomized Controlled Trial

Diseases of the Colon & Rectum
BACKGROUND: Frequent early postoperative complications of hemorrhoidectomy are thrombosis and edema of mucocutaneous “bridges.” OBJECTIVE: This study aimed to investigate the efficacy of micronized purified flavonoid fraction in preventing complications after elective ...
Yuliya Sergeevna Medkova, Inna Tulina, Valeriya Yudina, Ruslan Abdullaev, Vlada Shcherbakova, Ivan Novikov, Andrey Nikonov, Petr Tsarkov   +7 more
openaire   +2 more sources

STUDY OF PHARMACOLOGICAL ACTIVITY MICRONIZED PURIFIED FLAVONOID FRACTIONS OF SEA BUCKTHORN MEAL

Problems of Biological Medical and Pharmaceutical Chemistry, 2022
M.N. Shkolnikova, E.V. Averyanova, E.D. Rozhnov, I.A. Lupanova   +3 more
openaire   +1 more source

Efficacy and safety of micronized purified flavonoid fractions for the treatment of postoperative hemorrhoid complications: A systematic review and meta-analysis

Phytomedicine, 2022
Minhui Li, Wenfang guo, Baochang Zhou
exaly