Micronized Purified Flavonoid Fraction in Hemorrhoid Disease: A Systematic Review and Meta-Analysis [PDF]
Hemorrhoidal disease (HD) is a common and recurrent problem for many adults worldwide. Venoactive drugs, such as micronized purified flavonoid fraction (MPFF; Daflon®), have been used to treat HD and their clinical benefits have been demonstrated in previous meta-analyses of clinical trials.
Varut Lohsiriwat +2 more
exaly +5 more sources
Secondary Varicose Small Pelvic Veins and Their Treatment with Micronized Purified Flavonoid Fraction [PDF]
The aim of this study was to examine secondary varicose small pelvic veins (VSPV) and their treatment with micronized purified flavonoid fraction (MPFF). We examined 70 patients with a history of acute iliac thrombosis of > 1 year. Patients with urination difficulties associated with other symptoms (n = 24) received MPFF 1,000 mg once daily for 1 month.
Anton Tsukanov, Yurii T Tsukanov
exaly +5 more sources
The high prevalence of varicose veins has been established in numerous population studies. Currently, guidelines have been developed for the treatment of patients with varicose veins for various stages of chronic venous insufficiency.
H. M. Kurginyan, V. V. Raskin
doaj +3 more sources
Treatment of haemorrhoidal disease with micronized purified flavonoid fraction and sucralfate ointment. [PDF]
Hemorrhoidal disease is a very common disease characterized by the presence of a mucous prolapse of the rectum and by varicosis of the hemorrhoidal plexus. Medical therapy is mainly indicated for the treatment of symptoms such as bleeding, pain and itching.
Amaturo A, Meucci M, Mari FS.
europepmc +3 more sources
Chronic venous diseases of the lower extremities, including varicose veins, are one of the most common pathologies in modern society, affecting up to 73% of women and up to 56% of men.
E. A. Shcheglov, N. N. Alontseva
doaj +2 more sources
Daflon attenuates cisplatin-induced cerebellar neurotoxicity, anxiety-like behavior, and motor dysfunction by downregulating TLR4/NF-kB signaling [PDF]
Background Although cisplatin is an effective chemotherapy, a major downside is its toxicity, including cerebellar neurotoxicity, which is mediated by the induction of inflammation and oxidative stress.
F. B. Fidelis +9 more
doaj +2 more sources
Clinical Efficacy of Conservative Treatment with Micronized Purified Flavonoid Fraction in Female Patients with Pelvic Congestion Syndrome. [PDF]
Pelvic congestion syndrome (PCS) may be effectively managed with conservative treatment in certain patients. Treatment with venoactive drugs is common, but supportive data are limited. This study evaluated the clinical efficacy of micronized purified flavonoid fraction (MPFF) in women with PCS.In a single-blind, placebo-controlled study, women with ...
Akhmetzianov RV, Bredikhin RA.
europepmc +4 more sources
The Benefits of Micronized Purified Flavonoid Fraction (MPFF) Throughout the Progression of Chronic Venous Disease. [PDF]
At the 2019 European Venous Forum in Zurich Switzerland, a symposium entitled "State of the art: benefits of MPFF throughout CVD progression" was held to discuss the developing treatment strategies for patients at all stages of chronic venous disease (CVD).
Nicolaides AN.
europepmc +4 more sources
Micronized Purified Flavonoid Fraction (MPFF) for Patients Suffering from Chronic Venous Disease: A Review of New Evidence [PDF]
Jorge H Ulloa
exaly +2 more sources
Micronized purified flavonoid fraction in the treatment of hemorrhoidal disease
Hemorrhoidal disease (HD) is common in adults. Treatment is largely conservative, although more invasive procedures may be required. Venoactive drugs such as micronized purified flavonoid fraction (MPFF) are widely used, but a recent and comprehensive review of supporting evidence is lacking.
Philippe Godeberge +4 more
openaire +2 more sources

