Results 191 to 200 of about 26,946 (241)

Centromeric tandem repeats expansions in plateau zokor enhance chromosome stability for high-altitude adaptation. [PDF]

Genome Biol
Wang ZL, Shi LY, Liu XY, Yao XQ, Li MY, Wang QH, Wu H, Gong HS, Fu LY, Chang G, Wei LX, Nie WH, Su WT, Zhao B, Zhang T, Shi P.   +15 more
europepmc   +1 more source

It's a kind of MAGIC: uncovering the origins of chromosomal instability. [PDF]

Signal Transduct Target Ther
Gómez-Peregrina D, Serrano C.
europepmc   +1 more source

Chromothripsis and ecDNA initiated by N4BP2 nuclease fragmentation of cytoplasm-exposed chromosomes. [PDF]

Science
Krupina K, Goginashvili A, Baughn MW, Moore S, Steele CD, Nguyen AT, Zhang DL, Koeppel J, Trivedi P, Malhotra A, Jenkins D, Shiau AK, Miyake Y, Koga T, Miki S, Furnari FB, Campbell PJ, Alexandrov LB, Cleveland DW.   +18 more
europepmc   +1 more source

Different Effects of Antioxidants Against Ionizing Radiation: An Experimental Model of Micronuclei. [PDF]

Curr Issues Mol Biol
Alcaraz M, Achel DG, Garcia-Gamuz JA, Ruiz-Gómez MJ, Mercado-Díaz A, Alcaraz-Saura M, Navarro-Fernández JL, Olivares A.   +7 more
europepmc   +1 more source

The radiotherapy induced cyclic GMP-AMP-synthase re-localization and immune signature predicts HNSCC treatment efficacy. [PDF]

Commun Med (Lond)
Mekers VE, Span PN, Looman M, van den Bogaard L, Kho V, Melchers WJG, Bussink J, Kaanders JHAM, Ansems M, Adema GJ.   +9 more
europepmc   +1 more source

Micronuclei and Genome Chaos: Changing the System Inheritance

Genes, 2019
Micronuclei research has regained its popularity due to the realization that genome chaos, a rapid and massive genome re-organization under stress, represents a major common mechanism for punctuated cancer evolution.
Henry H Heng, Christine J Ye
exaly   +2 more sources

Some of the next articles are maybe not open access.

Related searches:

Genetic activities in micronuclei: Is the DNA entrapped in micronuclei lost for the cell?

Mutation Research - Reviews in Mutation Research, 2010
Micronuclei are good markers of genotoxic exposure in humans and their scoring has been extensively used to identify potential genotoxic agents. Micronuclei are also indicators of chromosomal instability, since the frequency of micronuclei is higher in tumour cells and cells with a defective DNA damage repair system or disrupted cell cycle checkpoint ...
Mariona Terradas, Marta Martín, Anna Genesca   +2 more
exaly   +3 more sources

Causes and consequences of micronuclei

Current Opinion in Cell Biology, 2021
Micronuclei are small membrane-bounded compartments with a DNA content encapsulated by a nuclear envelope and spatially separated from the primary nucleus. Micronuclei have long been linked to chromosome instability, genome rearrangements, and mutagenesis. They are frequently found in cancers, during senescence, and after genotoxic stress.
Ksenia, Krupina, Alexander, Goginashvili, Don W, Cleveland   +2 more
openaire   +2 more sources

Fate of micronuclei and micronucleated cells

Mutation Research - Reviews in Mutation Research, 2017
The present review describes available evidence about the fate of micronuclei and micronucleated cells. Micronuclei are small, extranuclear chromatin bodies surrounded by a nuclear envelope. The mechanisms underlying the formation of micronuclei are well understood but not much is known about the potential fate of micronuclei and micronucleated cells ...
Henning Hintzsche, Helga Stopper
exaly   +3 more sources

Biogenesis of micronuclei

Biochemistry (Moscow), 2016
The presence of micronuclei in a cell is an indicator of DNA damage and genetic instability. In this review, mechanisms of emergence of micronuclei, their functional activity, and pathways of elimination are discussed. It is supposed that morphological and functional varieties of micronuclei as well as their degradation pathways can be determined by ...
O P, Kisurina-Evgenieva, O I, Sutiagina, G E, Onishchenko   +2 more
openaire   +2 more sources