Results 211 to 220 of about 26,946 (241)
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Micronuclei in Diabetics and Smokers
Research Journal of Pharmacy and Technology, 2015Aim: This article reviews the MN assay with respect to oral buccal mucosa, which has been used since the 1980s to demonstrate the characteristics of micronuclei and frequency of micronuclei in smokers and diabetes. Objective: To compare the frequency of micronuclei and metanucleated anomalies in the oral mucosa of smokers and diabetes.
S. Bharathi, null Gheena
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Cinnamaldehyde-induced micronuclei in rodent liver
Mutation Research/Genetic Toxicology, 1994Cinnamaldehyde, a widely used flavoring agent, has so far been subjected to a limited range of genotoxicity tests, mainly carried out in vitro, which produced contradictory results. Therefore we have examined cinnamaldehyde using additional in vivo genotoxicity end-points.
E. Mereto +4 more
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The role of micronuclei in chromatin elimination
Žurnal obŝej biologiiMicronuclei are the extra-nuclear chromatin compartments separated from the primary nucleus and surrounded by their own nuclear envelope. For a long time it has been thought that micronuclei is the final stage of the pathological process in a cell. They have been used as biomarkers of the influence of genotoxic factors as well as of genome instability ...
Yu. R. Akhmadullina, P. O. Khomenko
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Chromosome painting of radiation-induced micronuclei
International Journal of Radiation Biology, 1996In this report, in situ hybridization with whole chromosome painting probes was used to paint radiation-induced micronuclei (MN) in three lymphoblastoid cells lines to investigate the frequency of radiation-induced MN. The results obtained for four different chromosomes showed that there was a significant deviation of the numbers of signal-positive MN ...
A, Slavotinek +4 more
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Micronuclei and Ageing in a Sample of Yugoslavian Population
Russian Journal of Genetics, 2002Instability in the organization and expression of the genetic material has been hypothesized as the basic mechanism of ageing. Aim of this study was to quantify the effect of ageing on spontaneous micronuclei (MN) frequency in peripheral blood lymphocytes.Analysis of Yugoslavian population sample (164 tested individuals, age 0-62 years) has performed ...
O, Milosevic-Djordjevic +4 more
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cGAS Conducts Micronuclei DNA Surveillance
Trends in Cell Biology, 2017DNA damage elicits a potent proinflammatory immune response. A collection of four papers now reveals that micronuclear DNA is a new cell intrinsic immunostimulatory molecule, and that accumulation of the immune sensor cyclic GMP-AMP synthase (cGAS) in micronuclei leads to a cell-cycle-dependent proinflammatory response following DNA damage.
Carina C, de Oliveira Mann +1 more
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Sex chromosomes, micronuclei and aging in women
Chromosoma, 1994Several studies on aneuploidy and aging have shown a significant increase in the loss of chromosomes in both males and females with age. Others have observed a significant increase in micronucleus formation in lymphocytes with age. The objectives of this investigation were to determine the relationship between sex chromosome loss and increased ...
J C, Hando, J, Nath, J D, Tucker
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Transient hypothermia induces micronuclei in mice
Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 1998We investigated the effect of hypothermia on micronucleus induction in mouse bone marrow cells. To induce hypothermia, we administered chlorpromazine, which was negative in an in vitro chromosome aberration test, at 3.13, 6.25, 12.5, 25, 50, and 100 mg/kg intraperitoneally.
S, Asanami, K, Shimono, S, Kaneda
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DNA Content of Micronuclei in Human Lymphocytes
International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine, 1985We have calculated the distribution of DNA contents in micronuclei (MN) induced by ionizing radiation in human lymphocytes on two assumptions: the MN arise from acentric chromosome fragments (ACF), and the ACF result from the random breakage and rejoining of chromosomes.
M, Pincu, H, Callisen, A, Norman
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Electromagnetic Fields and Micronuclei
2019Epidemiological findings indicate that exposure to high frequency electromagnetic fields (HF-ELF), which are used for mobile telecommunications, and also to extremely low frequency magnetic fields (from usage of electric current) may cause cancer in humans.
H. Al-Serori +4 more
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