Results 161 to 170 of about 59,469 (309)

Using the micronucleus assay to detect genotoxic effects of metal ions. [PDF]

open access: diamond, 1993
J Bérces   +4 more
openalex   +1 more source

Acute Toxicity and Genotoxicity of cMoL, a Lectin From Moringa oleifera Seeds With Antifungal Activity Against Cryptococcus Strains

open access: yesJournal of Applied Toxicology, Volume 46, Issue 2, Page 682-696, February 2026.
ABSTRACT Coagulant Moringa oleifera lectin (cMoL) is one of the compounds involved in the application of M. oleifera seeds for traditional water treatment methods. The present study highlights the new biotechnological potential of cMoL lectin as an antifungal agent against Cryptococcus neoformans B3501 and H99 and Cryptococcus gattii R265 strains ...
Matheus Cavalcanti de Barros   +16 more
wiley   +1 more source

A Novel Human Cellular System for Studying Normal Aging and for Anti‐Aging Discovery

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
This study introduces a human cellular aging model using placental trophoblasts (hTSC‐STBs) that mimics key aging features like senescence and genomic instability. It aligns with human tissue aging and responds to anti‐aging treatments, offering a scalable platform to screen potential therapies and bridge lab findings to clinical applications ...
Zhen Feng   +14 more
wiley   +1 more source

Genotoxicity assessment of Copaiba oil and its fractions in Swiss mice

open access: yesGenetics and Molecular Biology, 2012
Copaiba oil-resin, extracted from the trunk of Copaifera, and traditionally used in folk medicine in the treatment of various disorders, has been shown to be an effective antiinflamatory, antitumor, antitetanus, antiseptic and antiblenorrhagea agent. As,
Mara Ribeiro Almeida   +5 more
doaj  

Micronucleus counts correlating with male infertility: a clinical analysis of chromosomal abnormalities and reproductive parameters

open access: yesAsian Journal of Andrology
Investigating the correlation between micronucleus formation and male infertility has the potential to improve clinical diagnosis and deepen our understanding of pathological progression.
Shun-Han Zhang   +8 more
doaj   +1 more source

Sister chromatid exchange and micronucleus frequency in human lymphocytes of 1,650 subjects in an Italian population: I. Contribution of methodological factors [PDF]

open access: bronze, 1998
Roberto Barale   +9 more
openalex   +1 more source

Epigenomics‐guided precision oncology: Chromatin variants in prostate tumor evolution

open access: yesInternational Journal of Cancer, Volume 158, Issue 2, Page 314-332, 15 January 2026.
Abstract Prostate cancer is a common malignancy that in 5%–30% leads to treatment‐resistant and highly aggressive disease. Metastasis‐potential and treatment‐resistance is thought to rely on increased plasticity of the cancer cells—a mechanism whereby cancer cells alter their identity to adapt to changing environments or therapeutic pressures to create
Kira Furlano   +6 more
wiley   +1 more source

A Novel FGFR3‐Targeting Antibody‐Drug Conjugate Induces Tumor Cell Apoptosis through the cGAS–STING Pathway in Bladder Cancer

open access: yesAdvanced Science, Volume 13, Issue 4, 19 January 2026.
LZU‐WZLYCS01 is a novel FGFR3‐targeting ADC for bladder cancer with 7‐ethyl‐9‐fluorocamptothecin (A2) as its cytotoxic payload. LZU‐WZLYCS01 intracellularly releases A2, which targets MAD2L1 to activate the cGAS‐STING pathway and induce tumor cell apoptosis.
Shu Cui   +16 more
wiley   +1 more source

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