Results 171 to 180 of about 59,469 (309)
Advanced Science, Volume 13, Issue 3, 14 January 2026.Lactylation, linked to glycolysis, is poorly understood in regulation. It is found that LDHA is lactylated at Lys81/Lys318 by AARS1, boosting its activity and cellular lactylation via positive feedback in LUAD. Lactylation regulates NHEJ‐related proteins; their delactylation impairs NHEJ and increases cisplatin sensitivity, offering anticancer insights.
Jizhuo Li +11 more
wiley +1 more source
The effect of aging on the repeated-dose liver micronucleus assay using diethylnitrosamine [PDF]
, 2022 Kensuke Satomoto +6 more
openalex +1 more source
A Novel Family of Mobile Genetic Elements Is Limited to the Germline Genome in \u3cem\u3eTetrahymena Thermophila\u3c/em\u3e [PDF]
, 2002 In the ciliated protozoan Tetrahymena thermophila, extensive DNA elimination is associated with differentiation of the somatic macronucleus from the germline micronucleus.
Gershan, Jill A. +4 more
core +2 more sources
The Double Face of Base Excision Repair: Preventing and Triggering Double‐Strand Breaks
BioEssays, Volume 48, Issue 1, January 2026.Base excision repair is conserved from bacteria to man, robustly eliminating oxidized bases in DNA and reinserting the appropriate nucleotide to restore an intact double helix. Recent results describe conditions and mechanisms that misregulate long‐patch BER to generate double‐strand breaks, triggering chromosome fragmentation and cell death, altering ...
Susan M. Gasser
wiley +1 more source
Tandemly repeated C-C-C-C-A-A hexanucleotide of Tetrahymena rDNA is present elsewhere in the genome and may be related to the alteration of the somatic genome. [PDF]
, 1981 The ribosomal RNA genes of the Tetrahymena macronucleus exist as extrachromosomal, linear molecules. The termini of these molecules have been shown to contain the tandemly repeated hexanucleotide (C-C-C-C-A-A)n.
Blackburn, E, Gall, J, Yao, MC
core
Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.The study evaluates the phyto and cytogenotoxic activity of eight eugenol‐derived triazole compounds in Lactuca sativa. Compounds 2b and 2e exhibit high phytotoxicity, comparable to glyphosate, as well as cytotoxic and genotoxic effects associated with their greater hydrophilicity, highlighting them as promising candidates for the development of ...
Thayllon de Assis Alves +11 more
wiley +1 more source
Bifenthrin Under Scrutiny: Revisiting Toxicological Evidence Amid Regulatory Gaps
Journal of Applied Toxicology, Volume 46, Issue 1, Page 61-77, January 2026.ABSTRACT Despite growing health concerns, bifenthrin (BF) remains widely used for controlling agricultural and residential pests. However, different perspectives on its toxicological profile and regulatory framework warrant a revisit and update on BF regulation towards a robust risk‐safety assessment.
Caroline V. L. Moreira +10 more
wiley +1 more source