Background An in vitro micronucleus assay is a standard genotoxicity test. Although the technique and interpretation of the results are simple, manual counting of the total and micronucleus-containing cells in a microscopic field is tedious.
Hiromi Yoda +4 more
doaj +2 more sources
The effect of 5,6,7,8-tetrahydrobiopterin (BH4), an endogenous antioxidant, on γ-ray-induced micronucleus frequency was examined in RAW264.7 cells. Exogenously added BH4 reduced the γ-ray-induced micronucleus frequency. Treatment with 1 mM sepiapterin, a
Hori Mayumi, Kojima Shuji
doaj +2 more sources
Micronucleus study on breast cytology aspirate smears and its diagnostic utility
Background: Micronucleus is a small fragment of nucleus present in the cells which have undergone chromosomal damage. It is used as a biomarker of genomic damage. Aims: We aim to study the presence of micronucleus on breast cytology smears and the use of
Mary T Sylvia +2 more
doaj +2 more sources
Integrated Biomarker Assessment of Bifenthrin, Chlorpyrifos and Endosulfan Toxicity in Indigenous Carps (Catla catla and Labeo rohita): Oxidative Stress, Genotoxicity and Nuclear Alterations. [PDF]
Combined exposure to bifenthrin–chlorpyrifos and bifenthrin–endosulfan mixtures induced oxidative stress, genotoxicity and nuclear abnormalities in Catla catla and Labeo rohita. Antioxidant and DNA damage biomarkers provide sensitive tools for assessing pesticide‐related ecological risks in aquatic environments. ABSTRACT Background The extensive use of
Naz H +10 more
europepmc +2 more sources
Background: Panoramic and cephalometric radiography is very important for diagnosis, treatment plan, and evaluation of orthodontic treatment results. Panoramic and cephalometric radiography are frequently performed at the same time, causing DNA damage ...
Eha Renwi Astuti +3 more
doaj +1 more source
Radiation monitoring with plant-based biotas and an automated micronucleus scoring approach [PDF]
In this work, we investigated the response of the stem cells from the roots of Allium Cepa (meristems) to ionizing and non-ionizing radiations of different qualities.
d’Errico F. +10 more
doaj +1 more source
New direct contact approach to evaluate soil genotoxicity using the Vicia faba micronucleus test. [PDF]
A method to assess micronucleus (MN) induction in Vicia faba roots by direct contact exposure to a solid matrix was developed. The procedure comprised a 5-d germination period, as in the well-known method using aqueous extracts.
Cecchi, M. +6 more
core +1 more source
Assessment of the genotoxicity of Cu and Zn in raw and anaerobically digested slurry with the Vicia faba micronucleus test [PDF]
Genotoxicity of Cu and Zn was assessed by use of the micronucleus (MN) test on Vicia faba roots. Plants were exposed to various leachates of rawand anaerobically digested pig slurry, with maximum total concentrations of 200MCu and 600MZn.
Marcato, Claire-Emmanuelle +5 more
core +1 more source
The Effect of Lactobacillus acidophilus cell free extract on micronuclei in white male mice
This study dealt with the effect of Lactobacillus acidophilus concentrated filtrate on polychromatic erythrocyte. The result showed that Lactobacillus acidophilus concentrated filtrate caused a non significant decrease in micronucleus formation at first
Ruqaya M. Al-Ezy +3 more
doaj +1 more source
Assessment of the genotoxicity of quinolone and fluoroquinolones contaminated soil with the Vicia faba micronucleus test [PDF]
The genotoxicity of quinolone and fluroquinolones was assessed using the micronucleus (MN) test on Viciafaba roots by direct contact exposure to a solid matrix.
Khadra, Ahmed +20 more
core +1 more source

