Results 21 to 30 of about 16,798 (208)
Protective effects of acerola juice on genotoxicity induced by iron in vivo
Genetics and Molecular Biology, 2016 Metal ions such as iron can induce DNA damage by inducing reactive oxygen species (ROS) and oxidative stress. Vitamin C is one of the most widely consumed antioxidants worldwide, present in many fruits and vegetables, especially inMalpighia glabra L ...
Roberta Nunes Horta +7 more
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The coordination of nuclear envelope assembly and chromosome segregation in metazoans
Nucleus, 2020 The nuclear envelope (NE) is composed of two lipid bilayer membranes that enclose the eukaryotic genome. In interphase, the NE is perforated by thousands of nuclear pore complexes (NPCs), which allow transport in and out of the nucleus. During mitosis in
Shiwei Liu, David Pellman
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Evaluation of Fish Micronucleus Results in Turkish Ecogenotoxicological Studies
Çanakkale Onsekiz Mart University Journal of Marine Sciences and Fisheries, 2020 In recent years, ecotoxicological studies have been conducted around the world, especially in aquatic ecosystems. It is noteworthy that genotoxicity tests have been frequently used in the biomonitoring of pollution.
Gülşen GÖNEY , Cengiz GAZELOĞLU
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Association between human papillomavirus (HPV) DNA and micronuclei in normal cervical cytology [PDF]
Genetics and Molecular Biology, 2014 The aim of the present study was to investigate the association between HPV-DNA and micronucleus (MN) frequency in women with normal cervical cytology. A total of 158 normal cervical smears were analyzed cytologically.
Ana Paula Rebelo Cassel +4 more
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Nanomaterials, 2020 The contamination of freshwaters by heavy metals represents a great problem, posing a threat for human and environmental health. Cadmium is classified as carcinogen to humans and its mechanism of carcinogenicity includes genotoxic events. In this study a
Patrizia Guidi +9 more
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Reflections on the development of micronucleus assays [PDF]
Mutagenesis, 2010 These are personal reflections on the development of methods to use micronuclei as a measure of genetic damage and their use in research and in toxicology by four people who have been intimately involved with this work, a personal rather than a comprehensive history. About 6000 papers have been published using such methods in many tissues in vivo or in
John A, Heddle +3 more
openaire +2 more sources
Evaluation of the antigenotoxic and antioxidant activity induced by Croton antisyphiliticus [PDF]
Anais da Academia Brasileira de Ciências, 2020 This study aimed to investigate antigenotoxicity and antioxidant potential of extract, fractions and vitexin from C. antisyphiliticus. Methanolic extract was fractionated through solvents of increasing polarity.
REGILDO M.G. DA SILVA +6 more
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Genotoxicity of aluminium oxide, iron oxide, and copper nanoparticles in mouse bone marrow cells
Arhiv za Higijenu Rada i Toksikologiju, 2021 The aim of this study was to evaluate the genotoxic effects of Al2O3, Fe2O3, and Cu nanoparticles with chromosomal aberration (CA), micronucleus (MN), and comet assays on the bone marrow of male BALB/c mice.
Sadiq Rakhshinda +3 more
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source