Results 121 to 130 of about 13,726,259 (365)

Titanium Detected in Liver, Kidney, Spleen, and Intestine Is Not Related to Dose, Time, or Route of Exposure to Titanium Dioxide: A Systematic Review

Environmental Toxicology, EarlyView.
ABSTRACT Titanium dioxide (TiO2), used as a food additive (labeled E171 in Europe), was withdrawn from the European market in 2022. The E171 toxicity mechanism involves its uptake, oxidative stress, DNA damage, and inflammation. It has been hypothesized that the TiO2 accumulation nanoparticles (NPs) or E171 triggers tissue damage, and some studies have
Carmen Ximena Martínez‐Escutia, Estefany I. Medina‐Reyes, Eduardo Delgado‐Armenta, Yolanda I. Chirino   +3 more
wiley   +1 more source

CYTOKINESIS-BLOCK MICRONUCLEUS ASSAY IN HUMAN GLIOMA CELLS EXPOSED TO RADIATION

Image Analysis and Stereology, 2011
Biological tests are efficient in reflecting the biological influences of several types of generally harmful exposures. The micronucleus assay is widely used in genotoxicity studies or studies on genomic damage in general.
Jerzy Slowinski, Grazyna Bierzynska-Macyszyn, Urszula Mazurek, Maria Widel, Malgorzata Latocha, Monika Stomal, Miroslaw Snietura, Ryszard Mrowka   +7 more
doaj   +1 more source

First Assessment of Genetic Damage in the Speckled Cockroach (Nauphoeta cinerea) After Consumption of Lettuce (Lactuca sativa) Cultivated and Commercialized in Northeastern, Brazil

Environmental Toxicology, EarlyView.
ABSTRACT This study reports, for the first time, the use of the speckled cockroach Nauphoeta cinerea as a promising bioindicator for genotoxic monitoring. It was validated through control groups (both positive and negative) in addition to testing lettuce (Lactuca sativa ) samples from public street markets consumed by N. cinerea specimens in Pernambuco,
Aleson Aparecido da Silva, Eduardo Henrique da Silva Melo, Érima Maria de Amorim, Maria Gislaine Pereira, Claudia Rohde   +4 more
wiley   +1 more source

Progeny of Germ Line Knockouts of \u3cem\u3eASI2\u3c/em\u3e, a Gene Encoding a Putative Signal Transduction Receptor in \u3cem\u3eTetrahymena Thermophila\u3c/em\u3e, Fail to Make the Transition from Sexual Reproduction to Vegetative Growth [PDF]

, 2006
The ciliated protozoan Tetrahymena has two nuclei: a germ line micronucleus and a somatic macronucleus. The transcriptionally active macronucleus has about 50 copies of each chromosome.
Cole, Eric S., Karrer, Kathleen M., Li, Shuqiang, Udani, Rupa A., Yin, Lihui   +4 more
core   +1 more source

Scientific Opinion on Flavouring Group Evaluation 63, Revision 3 (FGE.63Rev3): aliphatic secondary alcohols, ketones and related esters evaluated by JECFA (59th and 69th meetings) structurally related to saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched-chain carboxylic acids evaluated by EFSA in FGE.07Rev4 [PDF]

, 2017
Publisher ...
Binderup, Mona-Lise, Bolognesi, Claudia, Brimer, Leon, Castle, Laurence, Cravedi, Jean-Pierre, Crebelli, Riccardo, de Fátima Tavares Poças, Maria, EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF), Engel, Karl-Heinz, Fowler , Paul, Franz, Roland, Grob, Konrad, Gürtler, Rainer, Husøy, Trine, Kovalkovičová, Natália, Kärenlampi, Sirpa, Marcon, Francesca, Marzin, Daniel, Mennes, Wim, Mosesso, Pasquale, Mulder, Gerard, Penninks, André, Rosaria Milana, Maria, Silano, Vittorio, Smith, Andrew, Sundh, Ulla Beckman, Tlustos, Christina, Wölfle , Detlef, Zorn, Holger, Zugravu, Corina-Aurelia   +29 more
core   +2 more sources

Application of image-recognition techniques to automated micronucleus detection in the in vitro micronucleus assay

Genes and Environment
Background An in vitro micronucleus assay is a standard genotoxicity test. Although the technique and interpretation of the results are simple, manual counting of the total and micronucleus-containing cells in a microscopic field is tedious.
Hiromi Yoda, Kazuya Abe, Hideya Takeo, Takeji Takamura-Enya, Ayumi Koike-Takeshita   +4 more
doaj   +1 more source

Genotoxicity evaluation of So-ochim-tang-gamibang (SOCG), a herbal medicine

BMC Complementary and Alternative Medicine, 2018
Background So-ochim-tang-gamibang (SOCG) is a traditional Korean medicine frequently used for depression in the clinical field. In this study, we evaluated the potential genotoxicity of SOCG using three standard batteries of tests as part of a safety ...
Mi Young Lee, Yang-Chun Park, Mirim Jin, Eunseok Kim, Jeong June Choi, In Chul Jung   +5 more
doaj   +1 more source

In Vivo Genotoxicity Evaluation of a No-Pain Pharmacopuncture Extract Using the Micronucleus Test. [PDF]

J Pharmacopuncture, 2023
Hwang JH, Jung C.
europepmc   +1 more source

Genotoxic effects of anesthetics in operating room personnel evaluated by micronucleus test

, 2013
Exposure to certain chemical agents causes damage to the genetic material. There is controversy about the genotoxic and/or mutagenic effect caused by acute or chronic anesthetics exposure.
T. K. Araujo, R. L. Silva-Grecco, F. Bisinotto, Nilson Camargos Roso, C. W. Pissetti, R. M. Cruz, M. Balarin   +6 more
semanticscholar   +1 more source

Evaluation of the Genotoxic and Antigenotoxic Effects of Chios Mastic Water by the In Vitro Micronucleus Test on Human Lymphocytes and the In Vivo Wing Somatic Test on Drosophila

PLoS ONE, 2013
Chios mastic gum, a plant-derived product obtained by the Mediterranean bush Pistacia lentiscus (L.) var. chia (Duham), has generated considerable interest because of its antimicrobial, anticancer, antioxidant and other beneficial properties. Its aqueous
D. Vlastos, D. Mademtzoglou, E. Drosopoulou, I. Efthimiou, T. Chartomatsidou, Christina Pandelidou, Melina-Ermioni Astyrakaki, Eleftheria Chalatsi, P. Mavragani-Tsipidou   +8 more
semanticscholar   +1 more source