Results 91 to 100 of about 13,742,305 (307)

Micronucleus induction by low doses of X-rays in Vicia faba root tips [PDF]

open access: yes, 1987
Studies on the micronucleus test in Vicia faba root tips (VM test) were carried out in order to estimate the effects at low doses of X-rays (1, 2, 4, 8 and 12 R). The control value of micronucleus frequency is about 0.44/1000 cells.
Gustavino, B   +4 more
core   +1 more source

Safety of 12‐Months Administration of Ashwagandha (Withania somnifera) Standardized Root Extract in Healthy Adults: A Prospective, Observational Study

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Ashwagandha, an adaptogen, is an important herb of Ayurveda used as a Rasayana for its various health benefits. This prospective, multi‐center, observational clinical study evaluates the safety (clinical and laboratory) of a standardized Ashwagandha Root Extract (ARE) on long‐term administration over 12 months. Male and female adults (N = 191)
Jaising Salve   +6 more
wiley   +1 more source

Automation and validation of micronucleus detection in the 3D EpiDerm™ human reconstructed skin assay and correlation with 2D dose responses

open access: yesMutagenesis, 2014
Recent restrictions on the testing of cosmetic ingredients in animals have resulted in the need to test the genotoxic potential of chemicals exclusively in vitro prior to licensing.
K. Chapman   +5 more
semanticscholar   +1 more source

Mesoporous Hollow Carbon Spheres/Nanofibers Anchored With Conductive Bimetallic for Efficient Microwave Absorption

open access: yesRare Metals, EarlyView.
ABSTRACT To break electromagnetic wave absorption (EMA) tech's single‐attenuation bottleneck, enhancing multi‐wave absorption synergy in composites is key for microstructure design. This study uses mesoporous hollow carbon spheres to make metal nanospheres with cobalt, iron, and nickel nanoparticles, then encapsulates them via electrospinning into a ...
Wei‐Lian Zhang   +10 more
wiley   +1 more source

To Dye or Not to Dye: Unraveling the Impact of Surface Chemistry on Cerium Oxide Nanoparticles–Cell Interactions

open access: yesSmall Science, EarlyView.
Fluorescent dye labeling enables nanoparticle imaging but may subtly alter their surface chemistry and biological behavior. This study compares dye‐labeled and unlabeled cerium oxide nanozymes, revealing changes in cellular uptake kinetics without affecting their final intracellular fate. Combined fluorescence and label‐free electron microscopy imaging
Kanika Dulta   +3 more
wiley   +1 more source

The micronucleus test—most widely used in vivo genotoxicity test— [PDF]

open access: yesGenes and Environment, 2016
Genotoxicity is commonly evaluated during the chemical safety assessment together with other toxicological endpoints. The micronucleus test is always included in many genotoxic test guidelines for long time in many classes of chemicals, e.g., pharmaceutical chemicals, agricultural chemicals, food additives.
openaire   +2 more sources

Ecotoxicological Evaluation of Organic Sunscreens Used Worldwide, Alone and in Mixture, on Terrestrial Plants

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT The environmental hazards of sunscreens are discussed worldwide. However, there are few ecotoxicological studies on these compounds alone for edaphic organisms, and none for their mixtures. Avobenzone (1 and 10 ng/L), octocrylene (10 and 100 μg/L), and oxybenzone (2 and 20 μg/L), alone and in binary combinations (between the lowest and the ...
Diego Espirito Santo   +6 more
wiley   +1 more source

Genotoxicity evaluation of alpha-linolenic acid-diacylglycerol oil

open access: yesToxicology Reports, 2016
The alpha-linolenic acid (ALA)-diacylglycerol (DAG) oil is an edible oil enriched with DAG (>80%) and ALA (>50%). Although DAG oil, which mainly consists of oleic and linoleic acids has no genotoxic concerns, the fatty acid composition could affect the ...
Hiroshi Honda   +5 more
doaj   +1 more source

Titanium Detected in Liver, Kidney, Spleen, and Intestine Is Not Related to Dose, Time, or Route of Exposure to Titanium Dioxide: A Systematic Review

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Titanium dioxide (TiO2), used as a food additive (labeled E171 in Europe), was withdrawn from the European market in 2022. The E171 toxicity mechanism involves its uptake, oxidative stress, DNA damage, and inflammation. It has been hypothesized that the TiO2 accumulation nanoparticles (NPs) or E171 triggers tissue damage, and some studies have
Carmen Ximena Martínez‐Escutia   +3 more
wiley   +1 more source

Ground and surface water for drinking: a laboratory study on genotoxicity using plant tests

open access: yesJournal of Public Health Research, 2012
Surface waters are increasingly utilized for drinking water because groundwater sources are often polluted. Several monitoring studies have detected the presence of mutagenicity in drinking water, especially from surface sources due to the reaction of ...
Donatella Feretti   +6 more
doaj   +1 more source

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