Results 81 to 90 of about 7,950 (195)

The micronucleus test: A method used in mutagenicity testing

Medical Journal of Indonesia, 1995
Micronucleus is a c7,16111ss1uc rontd bodl' v'hich contains chronatin nass (DNA). Micronuclei arise when replicating cell populatiotts are subiected to chrontosotttal breaknge by clastogens (agents causing chrontosonal breakrtge) or to chronrosotne loss by ntitotic spindle d1'sfunctiotr.
openaire   +2 more sources

Evaluation of genotoxicity and cytotoxicity of water samples from the Sinos River Basin, southern Brazil

Brazilian Journal of Biology
Some water bodies in the Sinos River Basin (SRB) have been suffering the effects of pollution by residential, industrial and agroindustrial wastewater. The presence of cytotoxic and genotoxic compounds could compromise the water quality and the balance ...
E Bianchi, A Goldoni, L Trintinaglia, G Lessing, CEM Silva, CA Nascimento, AL Ziulkoski, FR Spilki, LB Silva   +8 more
doaj   +1 more source

Prevalence of micronuclei in exfoliated uterine cervical cells from patients with risk factors for cervical cancer

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Pap smears are the most common and inexpensive screening method for cervical cancer. We analyzed micronucleus prevalence in exfoliated cervical mucosa cells, to investigate associations between increased numbers of micronuclei and ...
Lízia Maria Franco dos Reis Campos, Francisca da Luz Dias, Lusânia Maria Greggi Antunes, Eddie Fernando Candido Murta   +3 more
doaj   +1 more source

Safety evaluation of vitamin K2 (menaquinone-7) via toxicological tests

Scientific Reports
This study aims to evaluate the safety of MK-7 produced by fermentation process using a Bacillus subtilis var. natto strain for human ingestion via acute oral toxicity, repeated dose 90-day oral toxicity, 28-day recovery test, and genotoxicity tests. The
Sung-bong Hwang, Min-ju Choi, Hyeon-jeong Lee, Jeong-jun Han   +3 more
doaj   +1 more source

Feeding safety evaluation of Astragalus flower

Siliao yanjiu
In order to evaluate the feeding safety of Astragalus flower, acute oral toxicity tests, Ames mutagenicity tests, mammalian erythrocyte micronucleus tests, mouse spermatogonial chromosomal aberration tests, and a 90-day subacute toxicity test were ...
YU Kan-chao, LI Hui, MA De-zhi, LIU Ji-cheng, CUI Ying, ZHANG Ke-yong   +5 more
doaj  

Safety assessment of microbial Polysaccharide Sanxan. [PDF]

PLoS One
Zhang Y, Wu H, Pi J, Quan G, Chuo Q, Li X, Huang H.   +6 more
europepmc   +1 more source

Environmentally relevant concentrations of thiamethoxam cause cytotoxic and genotoxic damage in bullfrog (Lithobates catesbeianus) tadpoles. [PDF]

Ecotoxicology
De Oliveira AA, Barradas MC, Tomaz AA, da Silva Lima D, Assis JVB, Chaves AR, Vieira TB, Monteiro MS, Sarmento RA, de Souza Saraiva A, De Melo E Silva D.   +10 more
europepmc   +1 more source

Harnessing the power of an advanced in vitro 3D liver model and error-corrected duplex sequencing for the detection of mutational signatures. [PDF]

Mutagenesis
Conway GE, Chavanel B, Virard F, Shah UK, Burgum MJ, Evans SJ, Korenjak M, Thomas LE, Jenkins GJ, Zavadil J, Doak SH.   +10 more
europepmc   +1 more source

Genotoxicity  effects in Cancer Patients: Evaluation by Micronucleus and Comet Assays and Correlation with Biochemical and Hematological Indices. [PDF]

F1000Res
Dalaf Khalaf S, Talal Mahmood A, Fadhil Abbas A, Watheq Neamah R, Nasser Abdul Hameed R.   +4 more
europepmc   +1 more source

Associations of cumulative occupational benzene exposure with genotoxic and immunosenescence-related biomarkers: a cross-sectional study. [PDF]

Front Public Health
Xu W, Ruan X, He L, Zhang Y, Sun Y.
europepmc   +1 more source