Results 91 to 100 of about 7,624 (203)

Prevalence of micronuclei in exfoliated uterine cervical cells from patients with risk factors for cervical cancer

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Pap smears are the most common and inexpensive screening method for cervical cancer. We analyzed micronucleus prevalence in exfoliated cervical mucosa cells, to investigate associations between increased numbers of micronuclei and ...
Lízia Maria Franco dos Reis Campos, Francisca da Luz Dias, Lusânia Maria Greggi Antunes, Eddie Fernando Candido Murta   +3 more
doaj   +1 more source

Genotoxicity assessment of Elaeagnus angustifolia L. fruit extract (senjed) nanocapsule by in vitro and in vivo methods

Journal of Medicinal Plants, 2020
Background: Although initial studies on Elaeagnus Angustifolia L. Fruit Extract (Senjed) Nanocapsule showed its efficacy in osteoporosis in rat model as well as its significant role in elevating the serum calcium levels, there is no study on its possible
Negar Zamani, Masoomeh Heshmati, Sepideh Arbabi Bidgoli   +2 more
doaj  

Safety evaluation of vitamin K2 (menaquinone-7) via toxicological tests

Scientific Reports
This study aims to evaluate the safety of MK-7 produced by fermentation process using a Bacillus subtilis var. natto strain for human ingestion via acute oral toxicity, repeated dose 90-day oral toxicity, 28-day recovery test, and genotoxicity tests. The
Sung-bong Hwang, Min-ju Choi, Hyeon-jeong Lee, Jeong-jun Han   +3 more
doaj   +1 more source

Feeding safety evaluation of Astragalus flower

Siliao yanjiu
In order to evaluate the feeding safety of Astragalus flower, acute oral toxicity tests, Ames mutagenicity tests, mammalian erythrocyte micronucleus tests, mouse spermatogonial chromosomal aberration tests, and a 90-day subacute toxicity test were ...
YU Kan-chao, LI Hui, MA De-zhi, LIU Ji-cheng, CUI Ying, ZHANG Ke-yong   +5 more
doaj  

Safety assessment of the substance l-aspartic acid, <i>N</i>-benzoyl-, disodium salt for use in plastic food contact materials. [PDF]

EFSA J
EFSA Panel on Food Contact Materials (FCM), Lambré C, Crebelli R, da Silva MJ, Grob K, Heath E, Lampi E, Milana MR, Pronk M, Ščetar M, Theodoridis G, Van Hoeck E, Waegeneers N, Cariou R, Castle L, Di Consiglio E, Franz R, Barthélémy E, Marano R, Rivière G.   +19 more
europepmc   +1 more source

Variability and uncertainty of data from genotoxicity test guidelines: what we know and why it matters. [PDF]

Arch Toxicol
Raitano G, Pronk TE, Battistelli CL, Bossa C, Hatzi V, Nikolopoulou D, Chaideftou E, Tcheremenskaia O, Adam-Guillermin C, Audebert M, Mertens B, Paparella M.   +11 more
europepmc   +1 more source

Safety assessment of the substance (2E,2'E)-2,4,8,10-tetraoxaspiro[5.5]undecane-3,9-diylbis(2-methylpropane-2,1-diyl) bis(2-cyano-3-(3,4-dimethoxyphenyl)acrylate for use in plastic food contact materials. [PDF]

EFSA J
EFSA Panel on Food Contact Materials (FCM), Lambré C, Crebelli R, da Silva M, Grob K, Lampi E, Milana MR, Pronk M, Ščetar M, Theodoridis G, Van Hoeck E, Waegeneers N, Cariou R, Castle L, Di Consiglio E, Franz R, Barthélémy E, Comandella D, Rivière G.   +18 more
europepmc   +1 more source

Toxicological Evaluation of the Roots of <i>Ficus pandurata</i> Hance var. <i>angustifolia</i> Cheng. [PDF]

Food Sci Nutr
Chen Y, Fu Z, Ma F, Wang S, Pan J, Luo H, Liu Z, Chen J, Hu J, Zhang Y, Cheng K, Jin Y, Qu X.   +12 more
europepmc   +1 more source

How the methodology determines the outcome of the in vitro micronucleus assay (OECD TG 487): a comparison of the MicroFlow and the microscopic evaluation approach highlights the impact of cytotoxicity/cytostasis metrics in V79 cells for matrine. [PDF]

Arch Toxicol
Fischer BC, Musengi Y, Herrmann K, Kneuer C, König J.   +4 more
europepmc   +1 more source

Alizarin Dye: Toxicity, Genotoxicity, and Histopathological Alterations in Model Organisms. [PDF]

Environ Mol Mutagen
Rodrigues AR, Almeida GCF, Farias NO, Albuquerque AF, Oliveira AC, Cardoso JCM, Militão GFG, Cabral IM, Faustino CA, Vitorino JD, Botelho MT, Costa PM, Umbuzeiro GA.   +12 more
europepmc   +1 more source