Results 121 to 130 of about 15,743 (258)
Photochemistry and Photobiology, EarlyView.Exposure to solar ultraviolet radiation is the main etiologic driver of nonmelanoma skin cancers (NMSCs), including basal cell (BCC) and cutaneous squamous cell carcinomas (cSCC), which are the most prevalent types of cancers in the US. In this study, we demonstrate that the serine/threonine kinase Polo‐like kinase 4 (PLK4) is overexpressed in NMSCs ...
Mary A. Ndiaye +5 more
wiley +1 more source
Brazilian Journal of BiologyToxicity and genotoxicity tests were performed on root cells of Allium cepa in order to evaluate wastewater quality following an ECF cellulose bleaching process.
O. Roa, MC. Yeber, W. Venegas
doaj +1 more source
Photochemistry and Photobiology, EarlyView.Exposure to artificial light at night (ALAN), particularly at blue wavelengths, disrupts circadian rhythms by suppressing melatonin, thereby increasing cancer susceptibility. This systematic review consolidates evidence linking prolonged ALAN exposure to an elevated risk of breast and prostate tumors.
Gabriel Barboza +4 more
wiley +1 more source
Veterinary and Comparative Oncology, EarlyView.ABSTRACT Contaminants in municipal drinking water, specifically total trihalomethanes (TTHMs), are mutagenic. Exposures to TTHMs have been associated with urothelial carcinoma (UC) in both people and dogs. Mutations in the BRAF gene and other genomic copy number aberrations detected in voided urothelial cells with commercial CADET BRAF and BRAF‐PLUS ...
Janice O'Brien +6 more
wiley +1 more source
In vitro genotoxicity testing using the micronucleus assay in cell lines, human lymphocytes and 3D human skin models [PDF]
, 2017 The toxicological relevance of the micronucleus (MN) test is well defined: it is a multi-target genotoxic endpoint, assessing not only clastogenic and aneugenic events but also some epigenetic effects, which is simple to score, accurate, applicable in ...
Aardema, Marilyn J. +5 more
core
Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight
Experimental Physiology, EarlyView.Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley +1 more source
Chemistry &Biodiversity, Volume 23, Issue 5, May 2026.ABSTRACT Tetradenia riparia (Hochst.) Codd is a medicinal plant widely used in traditional medicine. However, comprehensive studies integrating its chemical composition, antioxidant capacity, and toxicological safety are still limited. This study aimed to characterize the phenolic content, antioxidant activity, phytochemical diversity, and ...
Caroline dos Santos Giuliani +11 more
wiley +1 more source
Frontiers in Dentistry, 2014 Radiography is one of the most valuable diagnostic tools used in comprehensive dental care. Although there is no safe level of radiation exposure, the possible risk associated with exposure to radiation, must be elucidated.
Pallak Arora +2 more
doaj
Drug Development Research, Volume 87, Issue 3, May 2026.ABSTRACT Osteosarcoma and rhabdomyosarcoma are the most common pediatric sarcomas, yet prognosis remains poor due to high relapse rates. This study investigates the repurposing of palbociclib (PB) and disulfiram (DS), alongside sodium selenite (SS), as potential therapeutic strategies.
María Ángeles Chico +6 more
wiley +1 more source
Brazilian Journal of BiologySome water bodies in the Sinos River Basin (SRB) have been suffering the effects of pollution by residential, industrial and agroindustrial wastewater. The presence of cytotoxic and genotoxic compounds could compromise the water quality and the balance ...
E Bianchi +8 more
doaj +1 more source