Results 201 to 210 of about 15,524 (254)
Some of the next articles are maybe not open access.
2014
Mercury, one of the most widely diffused and hazardous organ-specific environmental contaminants, exists in a wide variety of physical and chemical states, each of which with unique characteristics of target organ specificity (Aleo et al. 2002). In nature the different forms of mercury include the metallic form, inorganic compounds, as well as alkyl ...
openaire +1 more source
Mercury, one of the most widely diffused and hazardous organ-specific environmental contaminants, exists in a wide variety of physical and chemical states, each of which with unique characteristics of target organ specificity (Aleo et al. 2002). In nature the different forms of mercury include the metallic form, inorganic compounds, as well as alkyl ...
openaire +1 more source
In vivo micronucleus test using mouse hepatocytes
Mutation Research/Environmental Mutagenesis and Related Subjects, 1989The bone-marrow micronucleus (BMM) test is highly specific for clastogenic effects but its sensitivity is determined to a great extent by the substances tested, particularly by their metabolism. Some compounds, such as unstable mutagens or those which generate short-lived metabolites, are not detected in this test because the metabolites produced in ...
I, Cliet +3 more
openaire +2 more sources
Mutation Research/Environmental Mutagenesis and Related Subjects, 1993
In vivo somatic chromosome mutation tests are usually carried out using the bone marrow micronucleus test in the mouse. This test is also considered predictive for the study of clastogenic effects in germ cells. However, it has been reported that the sensitivity of the bone marrow micronucleus test is insufficient to detect unstable compounds or short ...
I, Cliet, C, Melcion, A, Cordier
openaire +2 more sources
In vivo somatic chromosome mutation tests are usually carried out using the bone marrow micronucleus test in the mouse. This test is also considered predictive for the study of clastogenic effects in germ cells. However, it has been reported that the sensitivity of the bone marrow micronucleus test is insufficient to detect unstable compounds or short ...
I, Cliet, C, Melcion, A, Cordier
openaire +2 more sources
Genetic toxicological testing of some dyes by the micronucleus test
Mutation Research/Genetic Toxicology, 1986Three widely used dyes, acridine orange, blue VRS and fast green FCF were administered to male mice in order to study the induction of gross chromosomal anomalies using the micronucleus test. All 3 compounds were shown to be clastogenic.
R N, Misra, B, Misra
openaire +2 more sources
The Micronucleus Test on Exfoliated Human Cells
1985The frequency of micronuclei in exfoliated human or animal cells can be used as an “endogenous dosimeter” present in tissues which are targets for carcinogenic and genotoxic agents and from which carcinomas arise. The application of the micronucleus test to exfoliated cells of various human tissues will provide evidence of exposure to carcinogens and ...
H F, Stich, W, Stich, M P, Rosin
openaire +2 more sources
The transplacental micronucleus test
Mutation Research/Environmental Mutagenesis and Related Subjects, 1980C J, Stoyel, A M, Clark
openaire +2 more sources
Strain difference in the micronucleus test
Mutation Research/Genetic Toxicology, 1988Abstract The Collaborative Study Group for the Micronucleus Test, a task group of the Environmental Mutagen Society of Japan, has earlier addressed the question of sex difference as a source of variation in the micronucleus test. Strain difference, another issue in test protocols requiring urgent clarification, was selected as the subject of the ...
openaire +1 more source
Strain difference in the micronucleus test. The Collaborative Study Group for the Micronucleus Test.
Mutation research, 1988The Collaborative Study Group for the Micronucleus Test, a task group of the Environmental Mutagen Society of Japan, has earlier addressed the question of sex difference as a source of variation in the micronucleus test. Strain difference, another issue in test protocols requiring urgent clarification, was selected as the subject of the second study ...
openaire +1 more source
Sex difference in the micronucleus test. The Collaborative Study Group for the Micronucleus Test.
Mutation research, 1986Since sex difference seemed to be one of the most urgent issues to be clarified among many parameters in protocols for the micronucleus test, the collaborative study group for the micronucleus test, consisting of members of the Japanese Environmental Mutagen Society, focused on this subject first. 20 clastogens were examined for sex-related differences
openaire +1 more source
Micronucleus test in reptiles: Current and future perspectives
Mutation Research - Genetic Toxicology and Environmental MutagenesisMicronucleus (MN) cell counting emerged in 1973-1975 as a valid alternative for characterizing chromosomal damage caused by different agents. It was first described in mammals, but its application was rapidly extended to other vertebrates, mainly fish.
Odetti, Lucia Magdalena +3 more
openaire +3 more sources