Results 141 to 150 of about 6,388 (235)

A modified lethal–potentially lethal model for oxygen‐mediated FLASH sparing in stem cell niches

Medical Physics, Volume 53, Issue 5, May 2026.
Abstract Background Ultra‐high dose rate (FLASH) irradiation can reduce normal‐tissue toxicity while preserving tumor control, but a mechanistic explanation consistent with classical radiobiology remains incomplete. In particular, oxygen‐depletion arguments based solely on bulk tissue oxygenation can appear inconsistent with clinically relevant ...
Sumin Zhou
wiley   +1 more source

A Microphysiological System with an Anaerobic Air‐Liquid Interface and Functional Mucus Layer for Coculture of Intestinal Bacteria and Primary Human Colonic Epithelium

Advanced Materials Interfaces
Coculture of intestinal bacteria with primary human intestinal epithelium provides a valuable tool for investigating host‐colon bacterial interactions and for testing and screening therapeutics.
Raehyun Kim, Nancy L. Allbritton
doaj   +1 more source

Perspective of using in vitro models to understand immunotherapy-induced cytokine release syndrome

Frontiers in Immunology
Since the TGN1412 clinical trial failure to predict cytokine release syndrome (CRS) during preclinical trials, alternative in vitro models have become increasingly important for identifying potential adverse outcomes in early drug development ...
Ethan Perkins, Ethan Perkins, Christopher Cooper, Emma Lund, Miriam Alb, Hannah Morgan, Birgit Fogal, Philip Hewitt, Alexander Mazein, Marek Ostaszewski, Katherina Sewald   +10 more
doaj   +1 more source

Aerospace medicine and biology: A continuing bibliography with indexes, supplement 130, July 1974 [PDF]

This special bibliography lists 291 reports, articles, and other documents introduced into the NASA scientific and technical information system in June ...

core   +1 more source

Enteric Nervous System Damage by Food Contaminants: A Pathway to Neurodegeneration?

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT The enteric nervous system (ENS), a key component of the gut–brain axis, has emerged as a critical player in the pathogenesis of Parkinson's disease (PD). It is the first neural system exposed to food contaminants (FCs)—a diverse group of ubiquitous toxic compounds fortuitously present in food derived from production, processing, storage, or ...
Helena Ramos, Ana Margarida Araújo, Isabel M. P. L. V. O. Ferreira, Miguel A. Faria   +3 more
wiley   +1 more source

Neutrophil Macrophage Crosstalk via Extracellular Vesicles Drives Reverse Migration in a Fully Human Model of Wound Healing

Advanced Science
Persistent neutrophilic inflammation can lead to tissue damage and chronic inflammation, contributing to non‐healing wounds. The resolution phase of neutrophilic inflammation is critical to preventing tissue damage.
Kehinde Adebayo Babatunde, Oluwadamilola Fatimat Babatunde, Adeel Ahmed, Wilmara Salgado‐Pabon, David J Beebe, Sheena C. Kerr   +5 more
doaj   +1 more source

Tailoring cardiac environment in microphysiological systems: an outlook on current and perspective heart-on-chip platforms [PDF]

, 2017
CRUZ MOREIRA, CATIA DANIELA, RASPONI, MARCO, REDAELLI, ALBERTO CESARE LUIGI, UGOLINI, GIOVANNI STEFANO, VISONE, ROBERTA   +4 more
core   +1 more source

Organ-on-a-Chip Models—New Possibilities in Experimental Science and Disease Modeling

Biomolecules
‘Organ-on-a-chip’ technology is a promising and rapidly evolving model in biological research. This innovative microfluidic cell culture device was created using a microchip with continuously perfused chambers, populated by living cells arranged to ...
Bartłomiej Wysoczański, Marcin Świątek, Anna Wójcik-Gładysz   +2 more
doaj   +1 more source

Engineering Challenges in Microphysiological Systems [PDF]

Future Science OA, 2017
openaire   +2 more sources

Development of an Easy-to-Fabricate Microdevice for Three-Dimensional Culture and Its Application to Glomerular Endothelial Cell Culture

Micromachines
The development of an organ-on-a-chip to reproduce organ functions requires the incorporation of a vascular network within the tissue to transport the necessary nutrients.
Miyu Yamazaki, Yasuko Kobayashi, Kiichi Sato   +2 more
doaj   +1 more source