Results 191 to 200 of about 6,641 (226)
Microphysiological Systems: Design, Fabrication, and Applications
ACS Biomaterials Science and Engineering, 2020 Microphysiological systems, including organoids, 3-D printed tissue constructs and organ-on-a-chips (organ chips), are physiologically relevant in vitro models and have experienced explosive growth in the past decades. Different from conventional, tissue culture plastic-based in vitro models or animal models, microphysiological systems recapitulate key
Kai Wang, Kun Man, Yong Yang
exaly +4 more sources
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Imaging microphysiological systems: a review
American Journal of Physiology-Cell Physiology, 2021Microphysiological systems (MPS), often referred to as “organ-on-chips,” are microfluidic-based in vitro models that aim to recapitulate the dynamic chemical and mechanical microenvironment of living organs. MPS promise to bridge the gap between in vitro and in vivo models and ultimately improve the translation from preclinical animal studies to ...
Samantha, Peel, Mark, Jackman
openaire +2 more sources
Microphysiological systems: What it takes for community adoption
Experimental Biology and Medicine, 2021 Microphysiological systems (MPS) are promising in vitro tools which could substantially improve the drug development process, particularly for underserved patient populations such as those with rare diseases, neural disorders, and diseases impacting pediatric populations.
Passley Hargrove-Grimes +2 more
exaly +3 more sources
Integrated biosensors for monitoring microphysiological systems
Lab on a Chip, 2022This review discusses the state-of-the-art integrated biosensors by providing specific examples, detailing their main advantages in monitoring MPSs, and describing the remaining challenges and potential future developments.
Lei Mou +10 more
openaire +2 more sources
Microphysiological systems of the placental barrier
Advanced Drug Delivery Reviews, 2020Methods to evaluate maternal-fetal transport across the placental barrier have generally involved clinical observations after-the-fact, ex vivo perfused placenta studies, or in vitro Transwell assays. Given the ethical and technical limitations in these approaches, and the drive to understand fetal development through the lens of transport-induced ...
Navein, Arumugasaamy +4 more
openaire +2 more sources
Microphysiological Systems for Cancer Immunotherapy Research and Development
Advanced Biology, 2023AbstractCancer immunotherapy focuses on the use of patients’ adaptive immune systems to combat cancer. In the past decade, FDA has approved many immunotherapy products for cancer patients who suffer from primary tumors, tumor relapse, and metastases. However, these immunotherapies still show resistance in many patients and often lead to inconsistent ...
Yansong Peng, Esak Lee
openaire +2 more sources
Human microphysiological systems for drug development
Science, 2021Organs-on-chips could be used to assess drug efficacy and support personalized ...
openaire +2 more sources
Microfluidic-based vascularized microphysiological systems
Lab on a Chip, 2018Microphysiological systems have emerged in the last decade to provide an alternative to in vivo models in basic science and pharmaceutical research.
Somin Lee +6 more
openaire +2 more sources
Developing Liver Microphysiological Systems for Biomedical Applications
Advanced Healthcare Materials, 2023AbstractMicrophysiological systems (MPSs), also known as organ chips, are micro‐units that integrate cells with diverse physical and biochemical environmental cues. In the field of liver MPSs, cellular components have advanced from simple planar cell cultures to more sophisticated 3D formations such as spheroids and organoids. Additionally, progress in
Jinglin Wang +4 more
openaire +2 more sources
Vascular microphysiological systems
Current Opinion in HematologyPurpose of review This review summarizes innovations in vascular microphysiological systems (MPS) and discusses the themes that have emerged from recent works. Recent findings Vascular MPS are increasing in complexity and ability to replicate tissue.
openaire +2 more sources