Results 1 to 10 of about 498,599 (357)

Opposing microRNA families regulate self-renewal in mouse embryonic stem cells

Nature, 2010
Collin Melton, Robert L Judson, Robert Blelloch   +2 more
exaly  

MicroRNA regulation by RNA-binding proteins and its implications for cancer

Nature Reviews Cancer, 2011
exaly  

A brain-specific microRNA regulates dendritic spine development

Nature, 2006
exaly  

miRNAs as Influencers of Cell-Cell Communication in Tumor Microenvironment [PDF]

Cells, 2020
microRNAs (miRNAs) are small noncoding RNAs that regulate gene expression at the posttranscriptional level, inducing the degradation of the target mRNA or translational repression.
Conti, Ilaria, Laface, Ilaria, Milani, Daniela, Neri, Luca M, Rimondi, Erika, Simioni, Carolina, Varano, Gabriele   +6 more
core   +3 more sources

MicroRNA [PDF]

Journal of Allergy and Clinical Immunology, 2018
MicroRNAs (miRNAs) are small endogenous RNAs that regulate gene-expression posttranscriptionally. MiRNA research in allergy is expanding because miRNAs are crucial regulators of gene expression and promising candidates for biomarker development.
Thomas X. Lu, Marc E. Rothenberg
  +5 more sources

MicroRNA: MicroRNAs Reach out into Dendrites [PDF]

Current Biology, 2006
A recent study has shown that miR-134, a brain-specific microRNA, is present in dendrites where it represses the local synthesis of the protein kinase LimK1; this is a novel form of translational regulation in dendrites and may have important physiological implications.
Tai, H., Schuman, E.
openaire   +3 more sources

Mesenchymal stem cell-derived exosome-educated macrophages alleviate systemic lupus erythematosus by promoting efferocytosis and recruitment of IL-17+ regulatory T cell

Stem Cell Research & Therapy, 2022
Background Anti-inflammatory polarized macrophages are reported to alleviate systemic lupus erythematosus (SLE). Our previous studies have demonstrated that exosomes from adipose-derived stem cells promote the anti-inflammatory polarization of ...
Mingchao Zhang, Takerra K. Johnson-Stephenson, Weiran Wang, Yang Wang, Jing Li, Limin Li, Ke Zen, Xi Chen, Dihan Zhu   +8 more
doaj   +1 more source

microRNA expression in peripheral blood cells following acute ischemic stroke and their predicted gene targets. [PDF]

, 2014
BackgroundmicroRNA (miRNA) are important regulators of gene expression. In patients with ischemic stroke we have previously shown that differences in immune cell gene expression are present.
Ander, Bradley P, Jickling, Glen C, Liu, Dazhi, Noblett, Dylan, Stamova, Boryana, Zhan, Xinhua   +5 more
core   +6 more sources

MicroRNA or Not MicroRNA? [PDF]

, 2011
The avalanche of next generation sequencing data has led to a rapid increase of annotated microRNAs in the last few years. Many of them are specific to individual species or rather narrow clades. A closer inspection of the current version of miRBase shows that dozens of entries conflict with other ncRNAs, in particular snoRNAs.With few exceptions ...
Langenberger, David, Bartschat, Sebastian, Hertel, Jana, Hoffmann, Steve, Tafer, Hakim, Stadler, Peter   +5 more
openaire   +2 more sources

Polynucleotide phosphorylase protects against renal tubular injury via blocking mt-dsRNA-PKR-eIF2α axis

Nature Communications, 2023
Renal tubular atrophy is a hallmark of chronic kidney disease. The study by Zhu et al. reveals the protective role of tubular polynucleotide phosphorylase (PNPT1) against renal atrophy by blocking the leakage of mitochondrial dsRNAs into cytoplasm where ...
Yujie Zhu, Mingchao Zhang, Weiran Wang, Shuang Qu, Minghui Liu, Weiwei Rong, Wenwen Yang, Hongwei Liang, Caihong Zeng, Xiaodong Zhu, Limin Li, Zhihong Liu, Ke Zen   +12 more
doaj   +1 more source