Results 221 to 230 of about 21,599 (235)

MicroRNA-210 overexpression predicts poorer prognosis in glioma patients

Journal of Clinical Neuroscience, 2014
MicroRNA-210 (miR-210) levels are elevated in many tumor types, are frequently associated with hypoxia induction, and are correlated with poor prognosis in many solid tumors. miR-210 regulates cell growth, angiogenesis, invasion, and apoptosis of many human tumors. In this study, we investigated the clinical significance of miR-210 expression in common
Nian-Sheng, Lai, Qing-Sheng, Dong, Hao, Ding, Zeng-Li, Miao, Yu-Chang, Lin   +4 more
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Prognostic evaluation of microRNA-210 expression in pediatric osteosarcoma

Medical Oncology, 2013
MicroRNA-210 (miR-210) plays important roles in the regulation of cell growth, angiogenesis, and apoptosis in different cancer type. Previous study of miRNA expression profiling found that miR-210 was significantly elevated in osteosarcoma samples. However, its roles in this disease have not been fully elucidated.
Haiqing, Cai, Lijun, Lin, Haikang, Cai, Mingjie, Tang, Zhigang, Wang   +4 more
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Administration of MicroRNA-210 Promotes Spinal Cord Regeneration in Mice

Spine, 2014
Experimental animal study of treatment of spinal cord injury (SCI).To investigate the therapeutic effects of administering microRNA-210 (miR-210) to promote angiogenesis in a mouse SCI model.Despite many previous studies regarding SCI, there is no established treatment in clinical practice.
Satoshi, Ujigo, Naosuke, Kamei, Hikmat, Hadoush, Yuki, Fujioka, Shigeru, Miyaki, Tomoyuki, Nakasa, Nobuhiro, Tanaka, Kazuyoshi, Nakanishi, Akiko, Eguchi, Toru, Sunagawa, Mitsuo, Ochi   +10 more
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Association of MicroRNA-210 and MicroRNA-155 with severity of preeclampsia

Pregnancy Hypertension, 2019
Preeclampsia (PE) is one of the leading causes of maternal and neonatal morbidity and mortality. Preeclampsia is associated with aberrant expression of several MicroRNAs which function as gene regulators. The present study aims to determine the expression of MicroRNA-210 and MicroRNA-155 in Preeclampsia, and to detect the association of MicroRNA-210 ...
Hanan Mohamed Gabr, Youssef, Elham Sayed, Marei   +1 more
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MicroRNA‐210 regulates human trophoblast cell line HTR‐8/SVneo function by attenuating Notch1 expression: Implications for the role of microRNA‐210 in pre‐eclampsia

Molecular Reproduction and Development, 2019
AbstractSuccessful pregnancy depends on the precise regulation of extravillous trophoblast cell invasion ability. MicroRNA‐210‐3p (miR‐210), which is increased in the placenta of pre‐eclampsia. Furthermore, miR‐210 could inhibit trophoblasts invasion and might act as a serum biomarker for pre‐eclampsia.
Rongli Wang, Weifang Liu, Xiaoping Liu, Xiaoxia Liu, Hui Tao, Di Wu, Yin Zhao, Li Zou   +7 more
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Abstract 838: microRNA-210 Regulates Endothelial Cell Response to Hypoxia

Circulation, 2007
Background . MicroRNAs (miRNAs) are small non-protein-coding RNAs that downregulate gene expression by inhibiting mRNA translation in mammalian cells. In this study, it was investigated miRNAs regulation and functional role in endothelial cell response to hypoxia. Methods and results.
Pasquale Fasanaro, Yuri D’Alessandra, Valeria Di Stefano, Roberta Melchionna, Sveva Romani, Giulio Pompilio, Maurizio C Capogrossi, Fabio Martelli   +7 more
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Silencing microRNA-210 in Hypoxia-Induced HUVEC-Derived Extracellular Vesicles Inhibits Hemangioma

Cerebrovascular Diseases, 2020
<b><i>Background:</i></b> Hemangioma (Hem) is a benign tumor commonly seen in infancy with a relative high morbidity. Human umbilical vein endothelial cell (HUVEC)-derived extracellular vesicles (EVs) are actively participated in Hem.
Jingwen, Ma, Xiaohua, Tao, Youming, Huang   +2 more
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MicroRNA-210 Mediates Hypoxic Pulmonary Hypertension in the Newborn Lamb

Hypertension
BACKGROUND: Pulmonary hypertension of the newborn is a life-threatening disorder characterized by elevated pulmonary vascular resistance due to maladaptation of the pulmonary circulation after birth. The pathogenesis and mechanisms underlying pulmonary hypertension of the newborn remain unclear, hindering the development of ...
Xiang-Qun Hu, Rui Song, Chiranjib Dasgupta, Stephen Twum-Barimah, Taiming Liu, Abu Ahmed, Shawn F. Hanson, Lubo Zhang, Arlin B. Blood   +8 more
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Serum microRNA-210 levels in different groups of chronic hepatitis B patients

Clinica Chimica Acta, 2015
It has been reported that hepatitis B virus (HBV) replication can be suppressed by microRNA-210 (miR-210). However, whether serum miR-210 levels can serve as disease parameters in patients with chronic hepatitis B (CHB) remains unclear.Serum miR-210 levels were quantified in 115 CHB patients and 20 healthy controls by real-time PCR.We found that serum ...
Fujun, Yu, Jianhuan, Yang, Jinsheng, Ouyang, Yihu, Zheng, Bicheng, Chen, Guojun, Li, Zhongqiu, Lu, Peihong, Dong, Jianjian, Zheng   +8 more
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Photodynamic therapy induces microRNA‐210 and ‐296 expression in HeLa cells

Journal of Biophotonics, 2010
AbstractApoptosis‐related microRNAs (miRNAs), the expression levels of which were observed to increase after photodynamic therapy (PDT), were identified as markers of PDT efficacy. miRNAs form a class of small endogenous RNAs that play important regulatory roles by targeting mRNA for cleavage or translational repression.
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