Results 21 to 30 of about 497,158 (357)
Serum microRNA Profiles Serve as Novel Biomarkers for Autoimmune Diseases
Frontiers in Immunology, 2018 Autoimmune diseases involve a complex dysregulation of immunity. Autoimmune diseases include many members [e.g., rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE)], and most of them are classified according to what organs and tissues are ...
Fangfang Jin +6 more
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Redox Biology, 2023 Acute kidney injury (AKI) presents a daunting challenge with limited therapeutic options. To explore the contribution of N6-methyladenosine (m6A) in AKI development, we have investigated m6A-modified mRNAs within renal tubular cells subjected to injuries
Wenwen Yang +8 more
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Salmonella produce microRNA-like RNA fragment Sal-1 in the infected cells to facilitate intracellular survival. [PDF]
, 2017 Salmonella have developed a sophisticated machinery to evade immune clearance and promote survival in the infected cells. Previous studies were mostly focused on either bacteria itself or host cells, the interaction mechanism of host-pathogen awaits ...
Chen, Xi +11 more
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Cells, 2022 Firstly, I apologize for the delayed publication of this Special Issue in the form of a book title [...]
openaire +3 more sources
Scientific Reports, 2017 The Warburg effect is a metabolic hallmark of cancer. Tumor cells rapidly adjust their energy source to glycolysis in order to efficiently proliferate in a hypoxic environment, but the mechanism underlying this switch remains incompletely understood ...
Fangfang Jin +8 more
doaj +1 more source
Biogenesis and function of extracellular miRNAs
ExRNA, 2019 Mature microRNAs (miRNAs) are 18–24-nucleotide non-coding RNAs with post-transcriptional regulatory functions and have been documented as an essential cornerstone of the genetic system.
Chihao Zhao, Xinlei Sun, Limin Li
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Regulation of neutrophil senescence by microRNAs [PDF]
, 2011 Neutrophils are rapidly recruited to sites of tissue injury or infection, where they protect against invading pathogens. Neutrophil functions are limited by a process of neutrophil senescence, which renders the cells unable to respond to chemoattractants,
A Bonauer +60 more
core +5 more sources
Nature Communications, 2017 Exosomes, vesicles secreted by cancer cells, have a role in cancer progression but the mechanisms regulating their biogenesis are mostly unknown. Here the authors show that PKM2, a rate-limiting glycolytic enzyme overexpressed in cancer cells, mediates ...
Yao Wei +14 more
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A novel and universal method for microRNA RT-qPCR data normalization [PDF]
, 2009 Gene expression analysis of microRNA molecules is becoming increasingly important. In this study we assess the use of the mean expression value of all expressed microRNAs in a given sample as a normalization factor for microRNA real-time quantitative PCR
De Weer, An +6 more
core +2 more sources
Shikonin Inhibits the Proliferation of Human Breast Cancer Cells by Reducing Tumor-Derived Exosomes
Molecules, 2016 Shikonin is a naphthoquinone isolated from the traditional Chinese medicine Lithospermum. It has been used in the treatment of various tumors. However, the effects of shikonin on such diseases have not been fully elucidated.
Yao Wei +6 more
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