Results 191 to 200 of about 31,660 (233)
Elucidating the contribution of gut‐organ axes will provide new insights for developing combined therapeutic strategies against sepsis‐associated multiple organ dysfunction. ABSTRACT Sepsis, a life‐threatening clinical syndrome precipitated by a maladaptive host response to infection, is associated with substantial morbidity and high mortality rates ...
Yichen Bao +7 more
wiley +1 more source
Exercise‐related microRNAs cel‐miR‐249‐3p and cel‐miR‐77‐5p in C. elegans regulate lifespan, fitness, mitochondrial morphology and membrane potential. Although lacking direct mammalian orthologs, H2O2‐induced microRNAs mmu‐miR‐181a‐5p and mmu‐miR‐378a‐3p regulate myogenesis, autophagy, mitochondrial content and respiration in murine myoblasts ...
Qin Xia +7 more
wiley +1 more source
Our study demonstrated that the LKB1–STRADα–MO25 complex was significantly downregulated in Duchenne muscular dystrophy (DMD) models, concurring with the disruption of mechano‐metabolic signaling. Treatment with the HDAC inhibitor, vorinostat, successfully restored LKB1 expression by suppressing specific repressor miRNAs.
Brigida Boccanegra +17 more
wiley +1 more source
Unfolding Plant Defence: Endoplasmic Reticulum Stress Signalling at the Plant‐Pathogen Interface
ABSTRACT The endoplasmic reticulum (ER) stress response, a conserved proteostasis network, has emerged as a central hub that reprograms plant immunity during pathogen attack. This review synthesises how plants harness ER‐stress signalling to mount multilayered defences and how pathogens have evolved counterstrategies to subvert these pathways.
Zhe Meng +8 more
wiley +1 more source
Circular RNAs in Lotus japonicus Responses to Nutrient Supply and Mesorhizobium Symbiosis
ABSTRACT Symbiotic interactions between legumes and rhizobia enable nitrogen fixation under low nutrient conditions. The establishment and function of symbiotic interactions require coordinated changes in gene expression in both the host and the microbe. Circular RNAs (circRNAs) are endogenous gene‐specific molecules that can regulate transcription and
Delecia Utley +3 more
wiley +1 more source
Efficiency and precision of microRNA biogenesis modes in plants. [PDF]
Moro B +7 more
europepmc +1 more source
Abstract figure legend This review utilized animal models of complicated human pregnancies that result in reduced fetal nutrient or oxygen delivery, or combined nutrient and oxygen delivery, to elucidate their independent and/or synergistic contributions to the development of high‐risk cardiac phenotypes.
Melanie R. Bertossa +8 more
wiley +1 more source
MicroRNA Biogenesis is Enhanced by Liposome-Encapsulated Pin1 Inhibitor in Hepatocellular Carcinoma. [PDF]
Sun D +8 more
europepmc +1 more source
TSC2 regulates microRNA biogenesis via mTORC1 and GSK3β. [PDF]
Ogórek B +8 more
europepmc +1 more source

