Results 91 to 100 of about 300,285 (315)

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

Gold(I)-Catalyzed Synthesis of 4H‑Benzo[d][1,3]oxazines and Biological Evaluation of Activity in Breast Cancer Cells

ACS Omega, 2022
Luis A. Segura-Quezada, Karina R. Torres-Carbajal, Narendra Mali, Dipak B. Patil, Mauricio Luna-Chagolla, Rafael Ortiz-Alvarado, Melissa Tapia-Juárez, Ixamail Fraire-Soto, Jorge Gustavo Araujo-Huitrado, Angelica Judith Granados-López, Rosalinda Gutiérrez-Hernández, Claudia Araceli Reyes-Estrada, Yamilé López-Hernández, Jesús Adrián López, Luis Chacón-García, César R. Solorio-Alvarado   +15 more
doaj   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Helicobacter pylori Is Associated with miR-133a Expression through Promoter Methylation in Gastric Carcinogenesis

Gut and Liver, 2018
Background/AimsTo investigate whether Helicobacter pylori eradication can reverse epigenetic silencing of microRNAs (miRNAs) which are associated with H.
Joo Hyun Lim, Sang Gyun Kim, Ji Min Choi, Hyo-Joon Yang, Joo Sung Kim, Hyun Chae Jung   +5 more
doaj   +1 more source

Recent Progress in Nanomaterials Modified Electrochemical Biosensors for the Detection of MicroRNA [PDF]

, 2021
Sze Shin Low, Daizong Ji, Wai Siong Chai, Jingjing Liu, Kuan Shiong Khoo, Sadegh Salmanpour, Fatemeh Karimi, B. Deepanraj, Pau Loke Show   +8 more
openalex   +1 more source

Bone Healing Around Implants in Normal and Medically Compromised Conditions: Osteoporosis and Diabetes

Advanced Healthcare Materials, EarlyView.
xx xx. ABSTRACT Osseointegration of orthopedic and dental implants is influenced by local and systemic factors, including their physicochemical surface properties and the patient's overall health status. Titanium and its alloys have been a longstanding standard for bone implants due to their innate biocompatibility and mechanical properties.
Dainelys Guadarrama Bello, Fabio Variola, Antonio Nanci   +2 more
wiley   +1 more source

Serum MicroRNA Levels as a Noninvasive Diagnostic Biomarker for the Early Diagnosis of Hepatitis B Virus-Related Liver Fibrosis

Gut and Liver, 2017
Background/AimsTo investigate the role of selected serum microRNA (miRNA) levels as potential noninvasive biomarkers for differentiating S0–S2 (early fibrosis) from S3–S4 (late fibrosis) in patients with a chronic hepatitis B virus (HBV) infection ...
Suxia Bao, Jianming Zheng, Ning Li, Chong Huang, Mingquan Chen, Qi Cheng, Kangkang Yu, Shengshen Chen, Mengqi Zhu, Guangfeng Shi   +9 more
doaj   +1 more source

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

Transformations in Breakthrough Research: The Emergence of Mirnas as a Research Routine in Molecular Biology

Open Information Science, 2018
Of the three main areas of science studies that emerged after WWII (Kawalec, 2018), namely social studies of science, economics of knowledge and scientometrics, it was the latter that gained particular prominence in science policy around the 1990’s with ...
Kawalec Paweł
doaj   +1 more source