Results 51 to 60 of about 283,349 (198)
Cancer Management and Research, 2020 Hang Li,1 Min Wang,2 Hui Zhou,3 Shan Lu,3 Bo Zhang4 1Department of Hepatobiliary and Pancreas Surgery, China-Japan Union Hospital, Changchun, People’s Republic of China; 2Department of Pathology, Jilin Provincial Cancer Hospital, Changchun, People ...
Li H, Wang M, Zhou H, Lu S, Zhang B
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The role of MicroRNAs in human cancer
Signal Transduction and Targeted Therapy, 2016 MicroRNAs (miRNAs) are endogenous, small non-coding RNAs that function in regulation of gene expression. Compelling evidences have demonstrated that miRNA expression is dysregulated in human cancer through various mechanisms, including amplification or ...
Yong Peng, C. Croce
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Aging and disease, 2018 Presbycusis (age-related hearing loss) is the most universal sensory degenerative disease in elderly people caused by the degeneration of cochlear cells. Non-coding microRNAs (miRNAs) play a fundamental role in gene regulation in almost every multicellular organism, and control the aging processes.
Jianguo Tang +3 more
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Journal of Orthopaedic Research, 2013 ABSTRACTmicroRNAs are small non‐coding RNAs that in the last decade have emerged as overarching regulators of gene expression. Their abundance, ability to repress a large number of target genes and overlapping target specificity indicate a complex network of interactions that is still being defined.
Gary Gibson, Hiroshi Asahara
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RNA-RNA competitive interactions: a molecular civil war ruling cell physiology and diseases
Exploration of Medicine, 2023 The idea that proteins are the main determining factors in the functioning of cells and organisms, and their dysfunctions are the first cause of pathologies, has been predominant in biology and biomedicine until recently.
Cristina Barbagallo +7 more
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Construction and analysis of a library of miRNA in gold-coloured mutant leaves of Ginkgo biloba L.
Folia Horticulturae, 2019 To gain insights into the regulatory networks of miRNAs related to golden colour formation in Ginkgo biloba leaves, we constructed an sRNA library of golden-green striped mutant leaves.
Li Weixing +5 more
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Regulation of mRNA translation and stability by microRNAs.
Annual Review of Biochemistry, 2010 MicroRNAs (miRNAs) are small noncoding RNAs that extensively regulate gene expression in animals, plants, and protozoa. miRNAs function posttranscriptionally by usually base-pairing to the mRNA 3'-untranslated regions to repress protein synthesis by ...
M. Fabian, N. Sonenberg, W. Filipowicz
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The role of the microRNA regulatory network in Alzheimer’s disease: a bioinformatics analysis
Archives of Medical Science, 2021 Introduction Alzheimer’s disease (AD) is a neurodegenerative disease which presents with an earlier age of onset and increased symptom severity. The objective of this study was to evaluate the relationship between regulation of miRNAs and AD.
Chenjing Sun +4 more
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MicroRNAs are Transported in Plasma and Delivered to Recipient Cells by High-Density Lipoproteins
Nature Cell Biology, 2011 Circulating microRNAs (miRNA) are relatively stable in plasma and are a new class of disease biomarkers. Here we present evidence that high-density lipoprotein (HDL) transports endogenous miRNAs and delivers them to recipient cells with functional ...
K. Vickers +4 more
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Vascular calcification: the role of microRNAs
Biomolecular Concepts, 2017 Vascular calcification represents the deposition of calcium phosphate salts in the tunica media of the vascular wall. It occurs during aging but is accelerated and pronounced in patients with diabetes mellitus, chronic kidney disease (CKD) and ...
Alkagiet Stelina, Tziomalos Konstantinos
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