Results 61 to 70 of about 283,349 (198)

Small RNA Species and microRNA Profiles are Altered in Severe Asthma Nanovesicles from Broncho Alveolar Lavage and Associate with Impaired Lung Function and Inflammation

open access: yesNon-Coding RNA, 2019
MicroRNAs are known to regulate important pathways in asthma pathology including the IL-6 and IFN pathways. MicroRNAs have been found not only within cells but also within extracellular vesicles such as exosomes. In this study, we particularly focused on
Ana S. Francisco-Garcia   +6 more
doaj   +1 more source

Investigation of the association of the RAN (rs14035) and XPO5 (rs11077) polymorphisms with venous thromboembolism

open access: yesRomanian Journal of Internal Medicine, 2023
Venous thromboembolism (VTE) is the third most common hemostatic disease worldwide. Studies have reported a role for microRNA (miRNA) in the homeostasis and development of VTE.
Alquraan Khloud M., Khabour Omar F.
doaj   +1 more source

Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs.

open access: yesGenes & Development, 2003
MicroRNAs (miRNAs) are initially expressed as long transcripts that are processed in the nucleus to yield approximately 65-nucleotide (nt) RNA hairpin intermediates, termed pre-miRNAs, that are exported to the cytoplasm for additional processing to yield
R. Yi, Yi Qin, I. Macara, B. Cullen
semanticscholar   +1 more source

Characterizing and Profiling microRNAs in Dogs Undergoing Induced Ischemic Brain Stroke After Middle Cerebral Artery Occlusion Under Fluoroscopic Guidance

open access: yesVascular Health and Risk Management, 2021
Khaled Z Alawneh,1 Liqaa A Raffee,2 Musa Ahmed Mohammed Alshehabat,3 Hazem Haddad,4 Saied A Jaradat5 1Department of Diagnostic Radiology and Nuclear Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan; 2Department of
Alawneh KZ   +4 more
doaj  

MicroRNA and cancer [PDF]

open access: yesMolecular Oncology, 2012
With the advent of next generation sequencing techniques a previously unknown world of non‐coding RNA molecules have been discovered. Non‐coding RNA transcripts likely outnumber the group of protein coding sequences and hold promise of many new discoveries and mechanistic explanations for essential biological phenomena and pathologies.
Jansson, Martin D, Lund, Anders H
openaire   +4 more sources

miR-190, CDK1, MCM10 and NDC80 predict the prognosis of the patients with lung cancer

open access: yesRomanian Journal of Laboratory Medicine, 2019
Lung cancer (LC), which includes small-cell lung carcinoma (SCLC) and non-small-cell lung carcinoma (NSCLC), is common and has a high fatality rate. This study aimed to reveal the prognostic mechanisms of LC.
Gao Li-Wei, Wang Guo-Liang
doaj   +1 more source

Characterization of microRNAs and lncRNAs in early-stage squamous cell carcinoma based on the analysis of TCGA datasets

open access: yesBiotechnology & Biotechnological Equipment, 2020
Lung squamous cell carcinoma (LUSC) is highly malignant with poor prognosis, causing prevalent mortality worldwide. Early-stage lung cancer can be distinguished through reliable early detection to urge timely treatment.
Weijing Liu   +8 more
doaj   +1 more source

Screening for circulating miR-208a and -b in different cardiac arrhythmias of dogs

open access: yesJournal of Veterinary Research, 2018
In recent years, the high sensitivity and specificity of novel miRNA biomarkers have been utilised for early diagnosis and treatment monitoring of various diseases.
Noszczyk-Nowak Agnieszka   +2 more
doaj   +1 more source

Role of microRNA in oncogenesis of pituitary tumors and their practical significance [PDF]

open access: yesТерапевтический архив, 2016
Microribonucleic acids (miRNAs) are a class of noncoding RNAs that regulate posttranscriptional gene expression. These molecules are regulators of cell proliferation, metabolism, apoptosis, and differentiation.
A M Lapshina   +4 more
doaj   +1 more source

MicroRNAs in the Hypothalamus [PDF]

open access: yesNeuroendocrinology, 2013
MicroRNAs (miRNAs) are short (∼22 nucleotides) non-coding ribonucleic acid (RNA) molecules that negatively regulate the expression of protein-coding genes. Posttranscriptional silencing of target genes by miRNA is initiated by binding to the 3′-untranslated regions of target mRNAs, resulting in specific cleavage and subsequent degradation of the mRNA ...
Meister, Björn   +2 more
openaire   +3 more sources

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