Results 81 to 90 of about 283,349 (198)

Gold(I)-Catalyzed Synthesis of 4H‑Benzo[d][1,3]oxazines and Biological Evaluation of Activity in Breast Cancer Cells

ACS Omega, 2022
Luis A. Segura-Quezada, Karina R. Torres-Carbajal, Narendra Mali, Dipak B. Patil, Mauricio Luna-Chagolla, Rafael Ortiz-Alvarado, Melissa Tapia-Juárez, Ixamail Fraire-Soto, Jorge Gustavo Araujo-Huitrado, Angelica Judith Granados-López, Rosalinda Gutiérrez-Hernández, Claudia Araceli Reyes-Estrada, Yamilé López-Hernández, Jesús Adrián López, Luis Chacón-García, César R. Solorio-Alvarado   +15 more
doaj   +1 more source

Involvement of Epigenetics in the Pathogenesis, Testing and Management of Coronavirus Disease 2019 (COVID-19) Pandemic: A Narrative Review

Pharmaceutical and Biomedical Research, 2021
Background: There is an intense search for the Coronavirus Disease 19 (COVID-19) cure, to stem the spread and burden of the disease worldwide. Studies revealed that epigenetic modifications impact the pathogenesis of some COVID-19 cases, which can be ...
Tajudeen Yahaya , Aminu Muhammed, Abdulhakeem Haruna, Esther Oladele, Usman Liman   +4 more
doaj  

Rapid Generation of MicroRNA Sponges for MicroRNA Inhibition

PLoS ONE, 2012
MicroRNA (miRNA) sponges are transcripts with repeated miRNA antisense sequences that can sequester miRNAs from endogenous targets. MiRNA sponges are valuable tools for miRNA loss-of-function studies both in vitro and in vivo. We developed a fast and flexible method to generate miRNA sponges and tested their efficiency in various assays. Using a single
Annelies Adema, Johan H. Gibcus, Bart-Jan Kroesen, Izabella Slezak-Prochazka, Nancy Halsema, Anke van den Berg, Mareike K. S. Richter, Joost Kluiver, Ye Ding, Chris Hettinga   +9 more
openaire   +6 more sources

microRNAs in action: biogenesis, function and regulation

Nature reviews genetics, 2023
Renfu Shang, Seungjae Lee, Gayan Senavirathne, E. Lai   +3 more
semanticscholar   +1 more source

OncomiR or Tumor Suppressor? The Duplicity of MicroRNAs in Cancer.

Cancer Research, 2016
MicroRNAs (miRNA) are short, noncoding RNAs whose dysregulation has been implicated in most, if not all, cancers. They regulate gene expression by suppressing mRNA translation and reducing mRNA stability. To this end, there is a great deal of interest in
Alexander A. Svoronos, D. Engelman, F. Slack   +2 more
semanticscholar   +1 more source

MicroRNAs in Sepsis

Biomedicines
Sepsis is an insidious and frequent condition of severe inflammation due to infections. Several biomarkers have been established for initial screening, but the non-specific nature of the existing biomarkers has led to the investigation of more sensitive and specific tools, such as microRNAs (miRs). These non-coding RNAs are involved in several diseases,
Asimina Valsamaki, Vasileios Vazgiourakis, Konstantinos Mantzarlis, Rodopi Stamatiou, Demosthenes Makris   +4 more
openaire   +3 more sources

MicroRNAs in health and disease

Journal of Clinical and Scientific Research, 2017
MicroRNAs (miRNAs) are a class of endogenous small non-coding RNAs about 21-25 nucleotides in length and account for 1%-5% of the genome. Ever since its discovery in 1993, these molecules have attracted researchers due to their crucial role in regulating
K Rama, P.V.L.N Srinivasa Rao, Aparna R Bitla   +2 more
doaj   +1 more source

MicroRNAs in plants [PDF]

, 2002
Brenda J. Reinhart, Earl G. Weinstein, Matthew W. Rhoades, Bonnie Bartel, David P. Bartel   +4 more
openalex   +1 more source

The copper microRNAs [PDF]

New Phytologist, 2016
SummaryCopper (Cu) microRNAs are upregulated by Cu deficiency and mediate the post‐transcriptional downregulation of transcripts that encode Cu proteins, suggesting a role directly related to Cu. However, expression and phenotypic analyses of copper microRNA mutants and over‐expressors have suggested roles mainly in tolerance to abiotic stresses.
openaire   +3 more sources

Signature microRNA expression profile is associated with spontaneous hypertension in African green monkey

Clinical and Experimental Hypertension, 2019
Chlorocebus aethiops sabaeus, the African Green monkey (AGM), has been proved to exhibit renal vascular remodeling and spontaneous hypertension.
Xiaojun Zhou, Jin Wang, Yunzhi Fa, Huahu Ye   +3 more
doaj   +1 more source