Results 191 to 200 of about 309,278 (337)

Metastatic potential of small posterior uveal melanomas

Acta Ophthalmologica, EarlyView.
Abstract Purpose To investigate the prevalence of aggressive traits in small posterior uveal melanomas (UM). Methods This retrospective, multicentre cohort study included 804 patients with small posterior UM (≤9 mm in largest basal diameter, ≤3 mm in thickness) from centres in the UK, Germany, and Sweden.
Gustav Stålhammar, Helen Kalirai, Sarah E. Coupland, Salvatore Grisanti, Svenja Rebecca Sonntag, Ayseguel Tura, Antonio Eleuteri, Rumana N. Hussain, Heinrich Heimann, Hannah Coudé Adam   +9 more
wiley   +1 more source

Genetic Diversity and Population Structure of <i>Rumex crispus</i> in South Korea Based on Genome-Derived Microsatellite Markers. [PDF]

Plants (Basel)
Kim EH, Kim KR, Hwang Y, Jeong JH, Goh J, Yu JN, Lee MH.   +6 more
europepmc   +1 more source

Microsatellites for Barren Brome (Anisantha sterilis) [PDF]

, 2000
J. M. Green, Keith J. Edwards, S. Usher, J. H. A. Barker, E. J. P. Marshall, R. J. Froud‐Williams, A. Karp   +6 more
openalex   +1 more source

The impact of Foxp3+ regulatory T‐cells on CD8+ T‐cell dysfunction in tumour microenvironments and responses to immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have been a breakthrough in cancer therapy, inducing durable remissions in responding patients. However, they are associated with variable outcomes, spanning from disease hyperprogression to complete responses with the onset of immune‐related adverse events.
Mikhaël Attias, Ciriaco A. Piccirillo
wiley   +1 more source

Relationships of three microsatellite loci with GSH-Px, SOD and Na<SUP>+</SUP>/K<SUP>+</SUP>-ATP enzyme activities and daily milk yield in different seasons in Holstein cows [PDF]

, 2010
Daqi Li, Yanxin Liu, Junmin Zhang, Hongbin Gao, Genlin Wang   +4 more
openalex   +1 more source

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen, Tamás Kovács, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

Genetic Population Structure of the Italian Wall Lizards <i>Podarcis siculus</i> (Squamata: Lacertidae): Insight From Nuclear DNA Markers. [PDF]

Ecol Evol
Senczuk G, Ripa C, Colangelo P, Castiglia R.   +3 more
europepmc   +1 more source

A century of theories of balancing selection

Biological Reviews, EarlyView.
ABSTRACT Traits that affect organismal fitness are often highly genetically variable. This genetic variation is vital for populations to adapt to their environments, but it is also surprising given that nature – after all – ‘selects’ the best genotypes at the expense of those that fall short.
Filip Ruzicka, Martyna K. Zwoinska, Debora Goedert, Hanna Kokko, Xiang‐Yi Li Richter, Iain R. Moodie, Sofie Nilén, Colin Olito, Erik I. Svensson, Peter Czuppon, Tim Connallon   +10 more
wiley   +1 more source

Genetic Diversity of <i>Apis cerana cerana</i> in the Lüliang Mountain Area Based on Molecular Markers. [PDF]

Genes (Basel)
Song C, Sun K, Song Y, Su Q, Yi X, Guo L, Guo Y.   +6 more
europepmc   +1 more source

Regulation of R‐Loop Dynamics by Proteins and Long Noncoding RNAs: An Emerging Paradigm for Cancer Treatment

Cancer Science, EarlyView.
R‐loops are three‐stranded nucleic acid structures whose dysregulation leads to genomic instability and cancer progression. This review summarizes the protein and lncRNA machineries that regulate R‐loop dynamics and discusses the therapeutic potential of targeting these pathways in cancer.
Miho M. Suzuki, Keiko Shinjo, Tatsunori Nishimura, Yutaka Kondo   +3 more
wiley   +1 more source