ABSTRACT Background Cervical clear cell adenocarcinoma (CCAC) and cervical endometrioid adenocarcinoma (CEAC) are rare and aggressive non‐HPV‐associated malignancies. Despite their histological similarities, these subtypes demonstrate distinct biological behaviors, presenting challenges in treatment and prognosis.
Jimiao Huang +12 more
wiley +1 more source
Study on predicting microsatellite instability in rectal cancer using T<sub>2</sub> mapping combined with ADC value. [PDF]
Zhao X, Hou Y, Ma H.
europepmc +1 more source
Multigene Germline Panel Testing in Gastric Cancer Patients in a Portuguese Population
ABSTRACT Background Gastric cancer is a heterogeneous disease with both environmental and genetic determinants. While Multigene Germline Panel Testing (MGPT) increasingly reveals hereditary predisposition, the prevalence and clinical significance of germline variants in Portuguese gastric cancer patients tested through institutional MGPT programs ...
B. Mourato +6 more
wiley +1 more source
<i>Bacteroides fragilis</i> toxin in colorectal tumors activates STAT3 and drives microsatellite instability. [PDF]
Mehmood MS, Danaf N.
europepmc +1 more source
Thyroid Metastasis From Colorectal Adenocarcinoma: A Case Report and Literature Review
Positron emission tomography‐computed tomography scan demonstrating thyroid metastasis from colorectal carcinoma in the context of metastatic disease. ABSTRACT Colorectal adenocarcinoma is one of the most common malignancies worldwide. Although metastases typically affect the liver, lungs, and peritoneum, thyroid involvement is extremely rare, with ...
Urías Hernandez Lopez +6 more
wiley +1 more source
Clinical characteristics of endometrial cancers with microsatellite instability-high and <i>BRCA1/2</i> mutations. [PDF]
Shan Y +6 more
europepmc +1 more source
ABSTRACT Signet ring cell carcinoma (SRCC) of the rectum is a rare histologic subtype and is often associated with aggressive behavior and poor outcomes, particularly in young patients. We report a 19‐year‐old male who presented with acute intestinal obstruction and was diagnosed with rectal SRCC, radiologically staged as cT2N1bM0, acknowledging the ...
Shivraj Sharma +6 more
wiley +1 more source
A Deep Learning-Based Approach for Explainable Microsatellite Instability Detection in Gastrointestinal Malignancies. [PDF]
Ciardiello L +6 more
europepmc +1 more source
ABSTRACT Background Myeloid‐derived suppressor cells (MDSCs) are important tumor microenvironment components in small cell lung cancer (SCLC). We successfully identified MDSCs expressing the surface marker CD33 in SCLC; nonetheless, whether CD33+MDSCs promote SCLC angiogenesis remains unclear.
Heran Cui +6 more
wiley +1 more source
Deficient mismatch repair/microsatellite instability-high colorectal cancer: current treatment paradigms, limitations and future perspectives. [PDF]
Storandt MH, Sinicrope FA.
europepmc +1 more source

