Results 191 to 200 of about 50,169 (235)

Successful treatment with pembrolizumab for microsatellite instability-high thymic carcinoma: A case report. [PDF]

Respir Med Case Rep
Sakamori Y, Hamada K, Kawachi H, Yamoto M, Fukao A, Terashita S, Watanabe K, Ikeue T, Sugita T.   +8 more
europepmc   +1 more source

Decoding Senescence‐Driven Heterogeneity in Early‐Onset Colorectal Cancer for Prognostic and Therapeutic Stratification

Cancer Science, Volume 117, Issue 3, Page 818-835, March 2026.
We uncovered pronounced and heterogeneous tumor senescence in EOCRC, independent of age. By integrating multi‐omics and single‐cell analyses, we developed EO‐Senscore, a prognostic tool that stratifies patients by immune phenotype and therapy response, enabling precision treatment using immunotherapy or senolytic agents. ABSTRACT Early‐onset colorectal
Du Cai, Mingru Mai, Rende Huang, Haoning Qi, Xingzhi Feng, Qianling Gao, Yinmeng Zhang, Chenghang Li, Xiaojian Wu, Yize Mao, Zihuan Yang, Feng Gao   +11 more
wiley   +1 more source

Microsatellite Instability in the Tumor Microenvironment: The Role of Inflammation and the Microbiome. [PDF]

Cancer Med
Vargas-Castellanos E, Rincón-Riveros A.
europepmc   +1 more source

Sex Differences in Cancer Immunotherapy—Clinical Evidence and Mechanisms With a Focus on NSCLC

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Accumulating evidence suggests that the immune system shows subtle but relevant differences between men and women. These differences may have an impact on cancer development and TME composition as well as responses to and adverse events elicited by immunotherapies.
Eva Krieghoff‐Henning, Balagopal Pai, Maike Collienne, Isabel Ben‐Batalla, Sonja Loges   +4 more
wiley   +1 more source

Integrating nutritional and inflammatory biomarkers in colorectal cancer management: Implications of microsatellite instability status. [PDF]

World J Gastrointest Surg
Xie RX, Xing YX, Sun NZ.
europepmc   +1 more source

Scat DNA Applications for Low‐Density Carnivore Survey: Techniques, Efficiency and Future Directions

Mammal Review, Volume 56, Issue 1, March 2026.
We reviewed 338 studies encompassing mostly Felidae, Canidae and Mustelidae species throughout the world, confirming scat DNA as a reliable genetic source for many applications. The findings here offer guidance for future studies on low‐density carnivores, helping to design cost‐effective research and improving data quality for conservation efforts ...
Marina Elisa de Oliveira, Fernando Gonçalves, Pedro M. Galetti Jr   +2 more
wiley   +1 more source

Computed tomography radiomics to predict microsatellite instability status and immunotherapy response in gastric cancer. [PDF]

Insights Imaging
Li Z, Ding Z, Lian Y, Liu Y, Wang L, Hu P, Zhang F, Luo Y, Qiu H.   +8 more
europepmc   +1 more source

Prognostic and predictive roles of microsatellite instability and mismatch repair deficiency in early-stage endometrial cancer: a structured narrative review. [PDF]

Obstet Gynecol Sci
Soleymani A, Hatami N, Jamkhane AE, Shabankhani K.   +3 more
europepmc   +1 more source

The cost-effectiveness analysis of immune checkpoint inhibitors for microsatellite instability-high/mismatch repair deficient advanced colorectal cancer. [PDF]

Sci Rep
Yang P, Pei Z, Zhou Y, Pei H.
europepmc   +1 more source

Emergency Colectomy for Obstruction in Microsatellite Instability Colonic Cancer: A Complete Response Following Neoadjuvant Immunotherapy. [PDF]

Cureus
Mohamed L, Alzaz L, Dounya D, Ouazni M, Soufi M.   +4 more
europepmc   +1 more source