Results 221 to 230 of about 124,795 (370)

First‐Line Genomic Profiling in Previously Untreated Advanced Solid Tumors: 1‐Year Follow‐Up of the FIRST‐Dx Study

open access: yesCancer Science, EarlyView.
In the 1‐year follow‐up data of the FIRST‐Dx study, the number of patients who received MBRT increased to 39 patients (22.7%) (Figure A and B) from our previous report (34 patients, 19.8%). The findings of this study imply that CGP testing before the standard of care for patients with advanced solid tumors could prove to be a clinically beneficial ...
Junichi Matsubara   +13 more
wiley   +1 more source

Novel microsatellite instability test of sebaceous tumours to facilitate low-cost universal screening for Lynch syndrome. [PDF]

open access: yesClin Exp Dermatol
Gallon R   +10 more
europepmc   +1 more source

Polo‐Like Kinase 1 Expression in Colorectal Cancer: Association With RAS Mutations

open access: yesCancer Science, EarlyView.
PLK1 expression may serve as a biomarker for adjuvant chemotherapy resistance in CRC. This study focused on the relationship between PLK1 expression and RAS mutation, which has been reported to be highly sensitive to PLK1 inhibitors. RAS mutation with high PLK1 expression predicts poorer survival in adjuvant‐treated CRC patients.
Yasushi Tanaka   +9 more
wiley   +1 more source

Microsatellite instability and promoter methylation as possible causes of NF1 gene inactivation in neurofibromas [PDF]

open access: bronze, 2000
Mirjam Luijten   +5 more
openalex   +1 more source

Digenic Inheritance of Monoallelic MUTYH and POLE Germline Variants in Adrenocortical Carcinoma: Implications for Tumorigenesis and Immunotherapy

open access: yesClinical Genetics, Volume 107, Issue 6, Page 699-701, June 2025.
Collision of monoallelic MUTYH and POLE germline variants in a patient with adrenocortical carcinoma who achieved a strong response to immunotherapy.
Jonathan Lopez   +11 more
wiley   +1 more source

Deep Gaussian process with uncertainty estimation for microsatellite instability and immunotherapy response prediction from histology. [PDF]

open access: yesNPJ Digit Med
Park S   +20 more
europepmc   +1 more source

A comparison of microsatellite instability in early onset gastric carcinomas from relatively low and high incidence European populations [PDF]

open access: green, 2000
Jeremy D. Hayden   +7 more
openalex   +1 more source

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