Results 231 to 240 of about 88,754 (292)

A phase 2 study of adjuvant chemotherapy with 5‐fluorouracil/leucovorin and oxaliplatin after lung metastasectomy for colorectal cancer (WJOG5810G)

Cancer, Volume 131, Issue 7, 1 April 2025.
Abstract Background The clinical significance of adjuvant chemotherapy after lung metastasectomy for colorectal cancer remains unknown. This phase 2 study evaluated adjuvant chemotherapy with modified 5‐fluorouracil/leucovorin and oxaliplatin (mFOLFOX6) after lung metastasectomy.
Nozomu Machida, Takehiro Okumura, Narikazu Boku, Junji Kishimoto, Tomohiro Nishina, Koichi Suyama, Yasuhisa Ohde, Katsunori Shinozaki, Hideo Baba, Shinya Tokunaga, Hisato Kawakami, Takashi Tsuda, Masahito Kotaka, Hiroyuki Okuda, Hisateru Yasui, Kentaro Yamazaki, Shuichi Hironaka, Kei Muro, Ichinosuke Hyodo   +18 more
wiley   +1 more source

Immune checkpoint inhibitor restores daily function in patient with microsatellite instability (MSI)-high advanced endometrial cancer and poor performance status. [PDF]

Int Cancer Conf J
Matsui A, Yoshida T, Takahashi Y, Fukuda K, Shimazu K, Taguchi D, Shinozaki H, Kodama N, Kato S, Waki H, Nanjo H, Shibata H.   +11 more
europepmc   +1 more source

Predicting Prognosis and Immunotherapy Response in Glioblastoma (GBM) With a 5‐Gene CAF‐Risk Signature

Cancer Reports, Volume 8, Issue 4, April 2025.
ABSTRACT Background Cancer‐associated fibroblasts (CAF) represent significant constituents within the extracellular matrix (ECM) across a range of cancers. Nevertheless, there exists a scarcity of direct proof concerning the function of CAF in glioblastoma (GBM).
Haifeng He, Min Yan, Ke Ye, Rui Shi, Luqing Tong, Shengxiang Zhang, Yu Zhu, Renya Zhan   +7 more
wiley   +1 more source

Application of immune checkpoint inhibitors and microsatellite instability in gastric cancer. [PDF]

World J Gastroenterol
Yan SY, Fan JG.
europepmc   +1 more source

BRCA2‐Related Hereditary Cancer Syndrome‐Associated Small Bowel Adenocarcinoma With Multiple BRCA2 Mutations: A Case Report and Review of the Literature

Cancer Reports, Volume 8, Issue 4, April 2025.
ABSTRACT Background Small bowel adenocarcinomas (SBAs) are rare and aggressive cancers. About one‐fifth of SBA patients have predisposing conditions; among them, there are also genetic tumor syndromes, including Lynch syndrome, familial adenomatous polyposis, and Peutz‐Jeghers syndrome.
Francesca Antoci, Tommaso Colella, Elena Biletta, Erica Travaglino, Giuseppe De Lisi, Erica Quaquarini, Giovanni Arpa, Alberto Maria Pisacane, Myriam Katja Paris, Salvatore Corallo, Antonio Di Sabatino, Francesco Leone, Alessandro Vanoli   +12 more
wiley   +1 more source

Which occurs first, ARID1A inactivation or microsatellite instability?: A comment to Yamamoto et al. (2024). [PDF]

Cancer Sci
Lee D.
europepmc   +1 more source

A myeloid IFN gamma response gene signature correlates with cancer prognosis

Clinical and Translational Medicine, Volume 15, Issue 4, April 2025.
IFGRNS score is a novel prognostic biomarker upregulated in myeloid lineage cells. IFGRNS score correlates with survival outcomes across multiple cancer types. IFGRNS score is associated with tumour pathology and immune microenvironment. IFGRNS score predicts immunotherapy response, with potential for clinical application. Abstract Background The IFN‐γ
Yuchao Zhang, Asma Khanniche, Yizhe Li, Zhenchuan Wu, Hailong Wang, Hongyu Zhang, Xiaoxue Li, Landian Hu, Xiangyin Kong   +8 more
wiley   +1 more source

Dynamics of blood microsatellite instability (bMSI) burden predicts outcome of a patient treated with immune checkpoint inhibitors: a case report of hyperprogressive disease. [PDF]

Front Immunol
Kravchuk D, Lebedeva A, Kuznetsova O, Kavun A, Taraskina A, Belova E, Grigoreva T, Veselovsky E, Mileyko V, Nikulin V, Nekrasova L, Tryakin A, Fedyanin M, Ivanov M.   +13 more
europepmc   +1 more source

Microsatellite instability, MMR gene expression and proliferation kinetics in colorectal cancer with famillial predisposition

, 2000
Bao Ping Wu
openalex   +1 more source