Results 251 to 260 of about 55,423 (289)

Predictive value of ¹⁸F-FDG PET/CT metabolic parameters for gastric cancer patients' microsatellite instability status. [PDF]

BMC Cancer
Liang B, Na Z, Wang K.
europepmc   +1 more source

Circulating hsa‐miR‐29c‐3p and VEGF‐A levels predict the response to FOLFIRI plus aflibercept in elderly metastatic colorectal cancer patients

European Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
Metastatic colorectal cancer (mCRC) patients who progress on oxaliplatin‐based chemotherapy benefit from second‐line treatment with FOLFIRI plus aflibercept. However, the absence of validated biomarkers for antiangiogenic therapies remains a challenge. Circulating levels of VEGF‐A and 13 miRNAs were analysed in 154 elderly mCRC patients.
Marta Toledano‐Fonseca, María Teresa Cano‐Osuna, Elena Élez, Javier Soto‐Alsar, David Páez, Ana Fernández‐Montes, Begoña Graña, Antonieta Salud, Alfonso Yubero, Ismael Macías, Guillermo Quintero, Carlos López‐López, Teresa Fernández‐Rodríguez, María Victoria García‐Ortiz, Javier Sastre, Pilar García‐Alfonso, Antonio Rodríguez‐Ariza, Enrique Aranda, on behalf of the Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)   +18 more
wiley   +1 more source

Evolution of microsatellite instability testing in a population-based cohort of patients with colorectal cancer in France in the years leading up to official recommendations. [PDF]

BMC Cancer
Wilson S, Guittet L, Gardy J, Alves A, Dupont B, Dejardin O, Bouvier V.   +6 more
europepmc   +1 more source

Treatment‐related changes in the prostate: past, present and future therapies

Histopathology, Volume 88, Issue 1, Page 40-52, January 2026.
Radiation therapy alters tumour morphology and immunoprofile in prostate cancer. Residual carcinoma shows distorted glandular architecture on H&E and loss of basal markers with preserved AMACR expression by immunohistochemistry, aiding in the recognition of treatment effect in prostate biopsies.
Katrina Collins, Liang Cheng
wiley   +1 more source

Glycolysis-Driven Immune Evasion in Microsatellite Instability-High Colorectal Cancer: An Integrated Single-Cell and Spatial Transcriptomics Study. [PDF]

Onco Targets Ther
Li C, Cai P, Zeng H, Li J, Hu H, Zhang J, Wu Z, Qin G, Deng Y.   +8 more
europepmc   +1 more source

Second malignancies in patients with deficient mismatch repair system/microsatellite instability-high colorectal cancer. [PDF]

Therap Adv Gastroenterol
Franques P, Moreau P, Evrard C, Chong-Si-Tsaon A, Frouin É, Auriault ML, Moulin V, Junca A, Godet J, Lebeau L, Aguillon R, Tachon G, Karayan-Tapon L, Tougeron D.   +13 more
europepmc   +1 more source

Real-World Impact of Metformin on Outcomes in Patients with Deficient DNA Mismatch Repair and Microsatellite Instability (dMMR/MSI) Colorectal Cancer Treated with Immune Checkpoint Inhibitors. [PDF]

Cancers (Basel)
Gupta G, Sadeghipour N, Bicer F, Elliott A, Hinton A, Lou E, Vanderwalde AM, Ozluk AA, Khushman MM, Malla M, Outlaw D, Hussaini SQ, El-Rayes BF, Akce M.   +13 more
europepmc   +1 more source

MNDA promotes immunosuppression in microsatellite instability-high colorectal cancer by facilitating PMN-MDSC infiltration via H3K18 lactylation. [PDF]

J Transl Med
Zhang X, Wang WB, Cai XY, Chen XQ, Feng Q, Yang Q, Li JB, Xiong W, Wu T.   +8 more
europepmc   +1 more source