Functional and immunological relevance of Anaplasma marginale major surface protein 1a sequence and structural analysis. [PDF]
Bovine anaplasmosis is caused by cattle infection with the tick-borne bacterium, Anaplasma marginale. The major surface protein 1a (MSP1a) has been used as a genetic marker for identifying A.
Alejandro Cabezas-Cruz+14 more
doaj +11 more sources
Genome-wide functional perturbation of human microsatellite repeats using engineered zinc finger transcription factors [PDF]
Summary: Repeat elements can be dysregulated at a genome-wide scale in human diseases. For example, in Ewing sarcoma, hundreds of inert GGAA repeats can be converted into active enhancers when bound by EWS-FLI1.
Y. Esther Tak+16 more
doaj +2 more sources
Simple Mathematical Model Of Pathologic Microsatellite Expansions: When Self-Reparation Does Not Work [PDF]
We propose a simple model of pathologic microsatellite expansion, and describe an inherent self-repairing mechanism working against expansion. We prove that if the probabilities of elementary expansions and contractions are equal, microsatellite expansions are always self-repairing.
Amos+48 more
arxiv +3 more sources
Functionally relevant microsatellites in sugarcane unigenes [PDF]
Background Unigene sequences constitute a rich source of functionally relevant microsatellites. The present study was undertaken to mine the microsatellites in the available unigene sequences of sugarcane for understanding their constitution in the ...
Singh Nagendra K+6 more
doaj +5 more sources
Abundant variation in microsatellites of the parasitic nematode Trichostrongylus tenuis and linkage to a tandem repeat [PDF]
An understanding of how genes move between and within populations of parasitic nematodes is important in combating the evolution and spread of anthelmintic resistance.
Adam, A.+5 more
core +3 more sources
Microsatellite distribution on sex chromosomes at different stages of heteromorphism and heterochromatinization in two lizard species (Squamata: Eublepharidae:
Background The accumulation of repetitive sequences such as microsatellites during the differentiation of sex chromosomes has not been studied in most squamate reptiles (lizards, amphisbaenians and snakes), a group which has a large diversity of sex ...
Kratochvíl Lukáš+2 more
doaj +5 more sources
Sequence determinants of human microsatellite variability [PDF]
Background Microsatellite loci are frequently used in genomic studies of DNA sequence repeats and in population studies of genetic variability. To investigate the effect of sequence properties of microsatellites on their level of variability we have ...
Jakobsson Mattias+3 more
doaj +5 more sources
Analyses of carnivore microsatellites and their intimate association with tRNA-derived SINEs [PDF]
Background The popularity of microsatellites has greatly increased in the last decade on account of their many applications. However, little is currently understood about the factors that influence their genesis and distribution among and within species ...
Bosch Montserrat+3 more
doaj +4 more sources
Impeding Transcription of Expanded Microsatellite Repeats by Deactivated Cas9 [PDF]
Belinda S. Pinto+10 more
openalex +2 more sources
Development and characterization of microsatellite markers for Chaeturichthys stigmatias (Actinopterygii: Gobiiformes: Gobiidae) based on restriction site-associated DNA sequencing (RAD-seq) [PDF]
Chaeturichthys stigmatias Richardson, 1844, a fish species of the family Gobiidae, is an offshore warm-temperate fish species and a dominant component of estuarine ecosystems.
Bingjie Chen+4 more
doaj +3 more sources