Results 11 to 20 of about 55,724 (327)

Microsatellite repeat instability and neurological disease [PDF]

BioEssays, 2009
AbstractOver 20 unstable microsatellite repeats have been identified as the cause of neurological disease in humans. The repeat nucleotide sequences, their location within the genes, the ranges of normal and disease‐causing repeat length and the clinical outcomes differ.
Judith R. Brouwer, Rob Willemsen, Ben A. Oostra   +2 more
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Characterization of Duck Microsatellite Repeat Sequences

Japan Agricultural Research Quarterly: JARQ, 2001
We cloned duck microsatellite repeat sequences from genomic DNA of an Indonesian native duck to evaluate the genetic relationships among native breeds of duck. A (CA) n - enriched library was constructed using the method of Takahashi et al. (1996) with modifications. In the library, 8.3% of the clones were CA-positive.
Hideaki Takahashi, Masahiro Satoh, Mitsuru Minezawa, T Purwadaria, Hardi Prasetyo   +4 more
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Frameshift mutations at coding mononucleotide repeat microsatellites in endometrial carcinoma with microsatellite instability [PDF]

Cancer, 2000
Microsatellite instability (MI) is a frequent occurrence in endometrioid carcinoma of the endometrium (EC). Several genes known to contain mononucleotide short tracts in their coding sequences (TGF-beta RII, IGFIIR, BAX, hMSH6, and hMSH3) are likely targets for mutations in these tumors.DNA from 24 patients with EC and MI was extracted from blood and ...
Lluís Catasús, Xavier Matías‐Guiu, Pilar Fernández Machín, Gian Franco Zannoni, Giovanni Scambia, Pierluigi Benedetti Panici, Jaime Prat   +6 more
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Discrepancy variation of dinucleotide microsatellite repeats in eukaryotic genomes [PDF]

Biological Research, 2009
To address whether there are differences of variation among repeat motif types and among taxonomic groups, we present here an analysis of variation and correlation of dinucleotide microsatellite repeats in eukaryotic genomes.
HUAN GAO, SHENGLI CAI, BINLUN YAN, BAIYAO CHEN, FEI YU   +4 more
doaj   +4 more sources

RNA biology of disease-associated microsatellite repeat expansions [PDF]

Acta Neuropathologica Communications, 2017
Microsatellites, or simple tandem repeat sequences, occur naturally in the human genome and have important roles in genome evolution and function. However, the expansion of microsatellites is associated with over two dozen neurological diseases. A common denominator among the majority of these disorders is the expression of expanded tandem repeat ...
Kushal J. Rohilla, Keith T. Gagnon
openalex   +5 more sources

Systematic microsatellite repeat expansion cloning and validation [PDF]

Human Genetics, 2020
Approximately 3% of the human genome is composed of short tandem repeat (STR) DNA sequence known as microsatellites, which can be found in both coding and non-coding regions. When associated with genic regions, expansion of microsatellite repeats beyond a critical threshold causes dozens of neurological repeat expansion disorders.
Kushal J. Rohilla, Katy N. Ovington, Adrian A. Pater, Maria Barton, Anthony J. Henke, Keith T. Gagnon   +5 more
openaire   +3 more sources

GTn Repeat Microsatellite Instability in Uterine Fibroids [PDF]

Frontiers in Genetics, 2019
Background: Type I collagen is a triple helix structure with two α1 and one α2 chains. Coordinated biosynthesis of α1 and α2 subunits is very important for tissue morphogenesis, growth, and repair. In contrast, abnormal deposition in response to proinflammatory cytokines is associated with organ dysfunction.
Bineta Kénémé, Mbacké Sembène, Mbacké Sembène   +2 more
openaire   +5 more sources

Characterization of Alu Repeats That Are Associated with Trinucleotide and Tetranucleotide Repeat Microsatellites [PDF]

Genome Research, 1997
The association of subclasses of Alu repetitive elements with various classes of trinucleotide and tetranucleotide microsatellites was characterized as a first step toward advancing our understanding of the evolution of microsatellite repeats. In addition, information regarding the association of specific classes of microsatellites with families of Alu
Chandri Yandava, Julie M. Gastier, Jacqueline C. Pulido, Tom Brody, Val C. Sheffield, Jeffrey C. Murray, Kenneth H. Buetow, Geoffrey M. Duyk   +7 more
openalex   +5 more sources

Isolation and characterization of microsatellite markers from Garcinia morella using next generation sequencing technology and cross-species amplification

Journal of Horticultural Sciences, 2023
The fruit-bearing medicinal tree, Garcinia morella, grows in the tropical rain forests of India’s Western Ghats, Indo-Chinese Himalayan regions and Sri Lanka. Its fruit rinds are used as a garnish and in seasoning during food preparation.
K V Ravishankar, R Vasudeva, B Hemanth, D Narendrababu, P Nischita, B S Sandya, B R Sthapit, V A Parthasarathy, V Ramanatha Rao   +8 more
doaj   +1 more source

Isolation and identification of a new set of microsatellite loci from Ucides cordatus genome [PDF]

Archives of Biological Sciences, 2015
A new set of microsatellite loci (simple sequence repeats, SSRs) from the overexploited mangrove crab Ucides cordatus is described in this study. Microsatellite isolation used a highly simplified and inexpensive protocol based on (i) multiple ...
Araújo Erlane S., Britto Fábio B., Carvalho Adriana M.F., Orasmo Gleice R., Diniz Fábio M.   +4 more
doaj   +1 more source