BMC Genetics, 2011 Background The accumulation of repetitive sequences such as microsatellites during the differentiation of sex chromosomes has not been studied in most squamate reptiles (lizards, amphisbaenians and snakes), a group which has a large diversity of sex ...
Kratochvíl Lukáš +2 more
doaj +1 more source
De novo Development and Characterization of Tetranucleotide Microsatellite Loci Markers from a Southeastern Population of the House Finch (Haemorhous mexicanus) [PDF]
, 2019 Microsatellites are short tandem repeats (e.g. TAGATAGA) of base pairs in a species’ genome. High mutation rates in these regions produce variation in the number of repeats across individuals that can be utilized to study patterns of population- and ...
Barron, Douglas G +2 more
core +3 more sources
Sequence determinants of human microsatellite variability
BMC Genomics, 2009 Background Microsatellite loci are frequently used in genomic studies of DNA sequence repeats and in population studies of genetic variability. To investigate the effect of sequence properties of microsatellites on their level of variability we have ...
Jakobsson Mattias +3 more
doaj +1 more source
Microsatellite instability (MSI, EMAST) in the pathogenesis of follicular lymphoma
Онкогематология, 2021 Background. Genetic instability, an important phenomenon involved in oncogenic transformation and tumor progression, is associated with the insufficiency of the multicomponent DNA repair complex, in particular, the nucleotide mismatch repair (MMR) system.
K. A. Sychevskaya +6 more
doaj +1 more source
Microsatellite Instability Causes Repeat Expansion and WRN Dependence [PDF]
Cancer Discovery, 2020 Abstract Cells with MSI accumulate unstable, structure-forming (TA)n repeats resolvable by the helicase WRN.
openalex +2 more sources
Measuring microsatellite conservation in mammalian evolution with a phylogenetic birth-death model. [PDF]
, 2012 Microsatellites make up ∼3% of the human genome, and there is increasing evidence that some microsatellites can have important functions and can be conserved by selection.
Buschiazzo, Emmanuel +4 more
core +1 more source
BJS (British Journal of Surgery), EarlyView., 2020 Recommendations for clinical and molecular identification of LS, surgical and endoscopic management of LS‐associated colorectal cancer and preventive measures for cancer were produced. The emphasis was on surgical and gastroenterological aspects of the cancer spectrum.
T. T. Seppälä +18 more
wiley +1 more source
Genetic diversity of peanut (Arachis hypogaea L.) and its wild relatives based on the analysis of hypervariable regions of the genome [PDF]
, 2004 BACKGROUND: The genus Arachis is native to a region that includes Central Brazil and neighboring countries. Little is known about the genetic variability of the Brazilian cultivated peanut (Arachis hypogaea, genome AABB) germplasm collection at the DNA ...
Ferreira, Marcio Elias +5 more
core +4 more sources
Analyses of carnivore microsatellites and their intimate association with tRNA-derived SINEs
BMC Genomics, 2006 Background The popularity of microsatellites has greatly increased in the last decade on account of their many applications. However, little is currently understood about the factors that influence their genesis and distribution among and within species ...
Bosch Montserrat +3 more
doaj +1 more source
Abundant variation in microsatellites of the parasitic nematode Trichostrongylus tenuis and linkage to a tandem repeat [PDF]
, 2006 An understanding of how genes move between and within populations of parasitic nematodes is important in combating the evolution and spread of anthelmintic resistance.
Adam, A. +5 more
core +1 more source