Functionally relevant microsatellites in sugarcane unigenes
Background Unigene sequences constitute a rich source of functionally relevant microsatellites. The present study was undertaken to mine the microsatellites in the available unigene sequences of sugarcane for understanding their constitution in the ...
Singh Nagendra K+6 more
doaj +1 more source
Compound Microsatellite Repeats: Practical and Theoretical Features [PDF]
Most linkage and population genetic studies that use microsatellites assume that the polymorphism observed at these loci is due simply to variation in the number of units of a single repeat. Variation is far more complex, however, for the numerous microsatellites that contain interruptions within the repeat or contain more than one type of repeat.
Laura N. Bull+2 more
openaire +3 more sources
Background The accumulation of repetitive sequences such as microsatellites during the differentiation of sex chromosomes has not been studied in most squamate reptiles (lizards, amphisbaenians and snakes), a group which has a large diversity of sex ...
Kratochvíl Lukáš+2 more
doaj +1 more source
MICdb3.0: a comprehensive resource of microsatellite repeats from prokaryotic genomes. [PDF]
The MICdb is a comprehensive relational database of perfect microsatellites extracted from completely sequenced and annotated genomes of bacteria and archaea. The current version MICdb3.0 is an updated and revised version of MICdb2.0. As compared with the previous version MICdb2.0, the current release is significantly improved in terms of much larger ...
Mudunuri SB, Patnana S, Nagarajaram HA.
europepmc +5 more sources
Microsatellite instability (MSI, EMAST) in the pathogenesis of follicular lymphoma
Background. Genetic instability, an important phenomenon involved in oncogenic transformation and tumor progression, is associated with the insufficiency of the multicomponent DNA repair complex, in particular, the nucleotide mismatch repair (MMR) system.
K. A. Sychevskaya+6 more
doaj +1 more source
Measuring microsatellite conservation in mammalian evolution with a phylogenetic birth-death model. [PDF]
Microsatellites make up ∼3% of the human genome, and there is increasing evidence that some microsatellites can have important functions and can be conserved by selection.
Buschiazzo, Emmanuel+4 more
core +1 more source
RNA Helicases in Microsatellite Repeat Expansion Disorders and Neurodegeneration
Short repeated sequences of 3−6 nucleotides are causing a growing number of over 50 microsatellite expansion disorders, which mainly present with neurodegenerative features. Although considered rare diseases in relation to the relatively low number of cases, these primarily adult-onset conditions, often debilitating and fatal in absence of a cure ...
Lydia M. Castelli+6 more
openaire +3 more sources
Sequence determinants of human microsatellite variability
Background Microsatellite loci are frequently used in genomic studies of DNA sequence repeats and in population studies of genetic variability. To investigate the effect of sequence properties of microsatellites on their level of variability we have ...
Jakobsson Mattias+3 more
doaj +1 more source
De novo Development and Characterization of Tetranucleotide Microsatellite Loci Markers from a Southeastern Population of the House Finch (Haemorhous mexicanus) [PDF]
Microsatellites are short tandem repeats (e.g. TAGATAGA) of base pairs in a species’ genome. High mutation rates in these regions produce variation in the number of repeats across individuals that can be utilized to study patterns of population- and ...
Barron, Douglas G+2 more
core +3 more sources
Analyses of carnivore microsatellites and their intimate association with tRNA-derived SINEs
Background The popularity of microsatellites has greatly increased in the last decade on account of their many applications. However, little is currently understood about the factors that influence their genesis and distribution among and within species ...
Bosch Montserrat+3 more
doaj +1 more source