Results 21 to 30 of about 68,764 (347)

Genome-wide distribution and organization of microsatellites in plants: an insight into marker development in Brachypodium. [PDF]

open access: yesPLoS ONE, 2011
Plant genomes are complex and contain large amounts of repetitive DNA including microsatellites that are distributed across entire genomes. Whole genome sequences of several monocot and dicot plants that are available in the public domain provide an ...
Humira Sonah   +8 more
doaj   +1 more source

GTn Repeat Microsatellite Instability in Uterine Fibroids [PDF]

open access: yesFrontiers in Genetics, 2019
Background: Type I collagen is a triple helix structure with two α1 and one α2 chains. Coordinated biosynthesis of α1 and α2 subunits is very important for tissue morphogenesis, growth, and repair. In contrast, abnormal deposition in response to proinflammatory cytokines is associated with organ dysfunction.
Bineta Kénémé   +2 more
openaire   +5 more sources

Characterization of Alu Repeats That Are Associated with Trinucleotide and Tetranucleotide Repeat Microsatellites [PDF]

open access: hybridGenome Research, 1997
The association of subclasses of Alu repetitive elements with various classes of trinucleotide and tetranucleotide microsatellites was characterized as a first step toward advancing our understanding of the evolution of microsatellite repeats. In addition, information regarding the association of specific classes of microsatellites with families of Alu
Chandri Yandava   +7 more
openalex   +5 more sources

Genetic population structure of the critically endangered stellate sturgeon (Acipenser stellatus) in the Black Sea basin: Implications for conservation

open access: yesAquatic Conservation: Marine and Freshwater Ecosystems, Volume 32, Issue 12, Page 1926-1939, December 2022., 2022
Abstract Stellate sturgeon (Acipenser stellatus) is a species of great conservation concern throughout its range. Over the past century, it has experienced a dramatic decline in abundance and distribution in the Black Sea basin. Information regarding the genetic structure of the species is very limited in the region, despite its crucial importance for ...
Daniela Nicoleta Holostenco   +16 more
wiley   +1 more source

Isolation and identification of a new set of microsatellite loci from Ucides cordatus genome [PDF]

open access: yesArchives of Biological Sciences, 2015
A new set of microsatellite loci (simple sequence repeats, SSRs) from the overexploited mangrove crab Ucides cordatus is described in this study. Microsatellite isolation used a highly simplified and inexpensive protocol based on (i) multiple ...
Araújo Erlane S.   +4 more
doaj   +1 more source

Isolation and characterization of microsatellite markers from Garcinia morella using next generation sequencing technology and cross-species amplification

open access: yesJournal of Horticultural Sciences, 2023
The fruit-bearing medicinal tree, Garcinia morella, grows in the tropical rain forests of India’s Western Ghats, Indo-Chinese Himalayan regions and Sri Lanka. Its fruit rinds are used as a garnish and in seasoning during food preparation.
K V Ravishankar   +8 more
doaj   +1 more source

Compound Microsatellite Repeats: Practical and Theoretical Features [PDF]

open access: yesGenome Research, 1999
Most linkage and population genetic studies that use microsatellites assume that the polymorphism observed at these loci is due simply to variation in the number of units of a single repeat. Variation is far more complex, however, for the numerous microsatellites that contain interruptions within the repeat or contain more than one type of repeat.
Laura N. Bull   +2 more
openaire   +3 more sources

Genomic characterization reveals distinct mutation landscapes and therapeutic implications in neuroendocrine carcinomas of the gastrointestinal tract

open access: yesCancer Communications, Volume 42, Issue 12, Page 1367-1386, December 2022., 2022
Abstract Background Neuroendocrine carcinomas of the gastrointestinal tract (GI‐NECs) remain a disease of grim prognosis with limited therapeutic options. Their molecular characteristics are still undefined. This study aimed to explore the underlying genetic basis and heterogeneity of GI‐NECs.
Huanwen Wu   +13 more
wiley   +1 more source

Multiplexed imaging of tumor immune microenvironmental markers in locally advanced or metastatic non‐small‐cell lung cancer characterizes the features of response to PD‐1 blockade plus chemotherapy

open access: yesCancer Communications, Volume 42, Issue 12, Page 1331-1346, December 2022., 2022
Abstract Background Although programmed cell death 1 (PD‐1) blockade plus chemotherapy can significantly prolong the progression‐free survival (PFS) and overall survival (OS) in first‐line settings in patients with driver‐negative advanced non‐small‐cell lung cancer (NSCLC), the predictive biomarkers remain undetermined.
Fengying Wu   +39 more
wiley   +1 more source

Microsatellite instability (MSI, EMAST) in the pathogenesis of follicular lymphoma

open access: yesОнкогематология, 2021
Background. Genetic instability, an important phenomenon involved in oncogenic transformation and tumor progression, is associated with the insufficiency of the multicomponent DNA repair complex, in particular, the nucleotide mismatch repair (MMR) system.
K. A. Sychevskaya   +6 more
doaj   +1 more source

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